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Cat. No.: HY-N15379

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Catharine

Catharine is an alkaloid found in Catharanthus roseus and can be synthesized in a cell-free system derived from Catharanthus roseus.

For research use only. We do not sell to patients.

CAS No.: 1355-31-3
Formula: C₄₆H₅₄N₄O₁₀
Molecular Weight:822.94

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

Catharine Chemical Structure

CAS No.: 1355-31-3

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

Catharine is an alkaloid found in Catharanthus roseus and can be synthesized in a cell-free system derived from Catharanthus roseus^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
HL-60	IC₅₀	56.2 μM Compound: 99	Antiproliferative activity against human HL-60 cells assessed as inhibition of cell growth incubated for 48 hrs by WST-1 assay Antiproliferative activity against human HL-60 cells assessed as inhibition of cell growth incubated for 48 hrs by WST-1 assay	[PMID: 36170798]
K562	IC₅₀	56.2 μM Compound: 99	Antiproliferative activity against human K562 cells assessed as inhibition of cell growth incubated for 48 hrs by WST-1 assay Antiproliferative activity against human K562 cells assessed as inhibition of cell growth incubated for 48 hrs by WST-1 assay	[PMID: 36170798]

Chemical Information

CAS No. 1355-31-3
Molecular Weight 822.94
Formula C₄₆H₅₄N₄O₁₀
SMILES

CC[C@]1([C@H]2OC(C)=O)[C@@]3([H])[C@](C(C4=C5)=CC([C@](C6=C(CCN7C=O)C8=CC=CC=C8N6)(CC(C/C(CC)=C\7)=O)C(OC)=O)=C5OC)(CCN3CC=C1)[C@](N4C)([H])[C@@]2(O)C(OC)=O
Structure Classification
- Alkaloids
- Indole Alkaloids
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Scott AI, et al. Letter: Biosynthesis of the indole alkaloids. A cell-free system from Catharanthus roseus. J Am Chem Soc. 1975 Nov 12;97(23):6906-8. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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