69579-74-4
Chemical Structure
Adustin
- CAS No.: 69579-74-4
- Formula:C11H8O3
- Molecular Weight:188.18
InChIKey: RAFAVNTVTXJMAQ-UHFFFAOYSA-N
SMILES: O=C(C1=C(O)C=CO1)C2=CC=CC=C2
Biological Activity: Adustin, an antifungal antibiotic, is a polypeptide with translation-inhibiting activity. Adustin inhibits translation in a cell-free rabbit reticulocyte lysate system with an IC50 of 0.34 μM[1][2].
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Adustin | Adustin, an antifungal antibiotic, is a polypeptide with translation-inhibiting activity. Adustin inhibits translation in a cell-free rabbit reticulocyte lysate system with an IC50 of 0.34 μM. | |||||||||||||||||||||
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- [1]. Ng TB, et al. Adustin, a small translation-inhibiting polypeptide from fruiting bodies of the wild mushroom Polyporus adusta. Peptides. 2004 Apr;25(4):689-92. [Content Brief]
- [2]. Z. Guan-Ping, et al. Adustin, a new antifungal antibiotic 1. Production, isolation and properties of adustin. Acta Microbiologica Sinica, 1978, Vol. 18, No. 4, 317-319 ref. 2.
Keywords