2883627-66-3
2883627-66-3
Chemical Structure
α-Synuclein-IN-25
- CAS No.: 2883627-66-3
- Formula:C22H14F2N2O4
- Molecular Weight:408.35
InChIKey: QSQJXJDEIVDXEH-WTDSWWLTSA-N
SMILES: O=C(C=C1)C(/C=C/C(NC(C=C2)=CC=C2NC(C3=CC(F)=C(C=C3)F)=O)=O)=CC1=O
Biological Activity: α-Synuclein-IN-25 is a quinone-acid hybrid and also an α-synuclein aggregation inhibitor with an IC50 of 3.0 μM. α-Synuclein-IN-25 dissociates preformed α-Syn aggregates, inhibits their re-aggregation, scavenges reactive oxygen species, and reduces the formation of α-Syn inclusions in neuronal cells. α-Synuclein-IN-25 can be used in the research of Parkinson's disease[1].
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α-Synuclein-IN-25 | α-Synuclein-IN-25 is a quinone-acid hybrid and also an α-synuclein aggregation inhibitor with an IC50 of 3.0 μM. α-Synuclein-IN-25 dissociates preformed α-Syn aggregates, inhibits their re-aggregation, scavenges reactive oxygen species, and reduces the formation of α-Syn inclusions in neuronal cells. α-Synuclein-IN-25 can be used in the research of Parkinson's disease. | |||||||||||||||||||||
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References
Keywords
