16 Results for "

connective tissue growth factor

" in MedChemExpress (MCE) Product Catalog:
Products (16)

16 Results for "connective tissue growth factor" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-P99288
CAS No.: 946415-13-0
Synonyms: Pamrevlumab; Anti-Human CTGF Recombinant Antibody

Target:  

Apoptosis

Research Areas:  

Inflammation/Immunology

FG-3019 (Pamrevlumab) is a recombinant human antibody that binds to connective tissue growth factor (CTGF). FG-3019 can be used for the research of idiopathic pulmonary fibrosis (IPF) .
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2
2 Cited Publications
Cat. No.: HY-P72153
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CCN2; CCN Family Member 2; Prev. CTGF; IBP-8; IGFBP8; SEMDLSL; connective tissue growth factor; IGFBP-8; Hypertrophic Chondrocyte-Specific Protein 24; NOV2; Insulin-Like growth factor-Binding Protein 8; KMD; IGF-Binding Protein 8; Cellular Communication N
Species:  
Human
Source:  
E. coli
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2
2 Cited Publications
Cat. No.: HY-P72154
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CCN2; CCN Family Member 2; Prev. CTGF; IBP-8; IGFBP8; SEMDLSL; connective tissue growth factor; IGFBP-8; Hypertrophic Chondrocyte-Specific Protein 24; NOV2; Insulin-Like growth factor-Binding Protein 8; KMD; IGF-Binding Protein 8; Cellular Communication N
Species:  
Mouse
Source:  
E. coli
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1
1 Cited Publications
Cat. No.: HY-120006A
CAS No.: 1408311-94-3
Purity:  99.42%
Target:  

ERK

Research Areas:  

Cardiovascular Disease

(rel)-AR234960 is a selective and competitive agonist of the G protein-coupled receptor MAS. (rel)-AR234960 binds to the MAS receptor to activate the downstream ERK1/2 signaling pathway, inducing the expression of connective tissue growth factor (CTGF) and its downstream collagen subtype genes (such as COL1A1, COL3A1). (rel)-AR234960 promotes collagen synthesis in cardiac fibroblasts through the MAS-ERK1/2-CTGF pathway and aggravates extracellular matrix remodeling. (rel)-AR234960's in vitro effect can be blocked by the MAS inverse agonist AR244555 and MEK1 inhibitor. (rel)-AR234960 regulates the expression of cardiac fibrosis-related genes and can be used in the study of heart failure .
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1
1 Cited Publications
Cat. No.: HY-P70106
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCN2; CCN Family Member 2; Prev. CTGF; IBP-8; IGFBP8; SEMDLSL; connective tissue growth factor; IGFBP-8; Hypertrophic Chondrocyte-Specific Protein 24; NOV2; Insulin-Like growth factor-Binding Protein 8; KMD; IGF-Binding Protein 8; Cellular Communication N
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P70602
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CCN2; CCN Family Member 2; Prev. CTGF; IBP-8; IGFBP8; SEMDLSL; connective tissue growth factor; IGFBP-8; Hypertrophic Chondrocyte-Specific Protein 24; NOV2; Insulin-Like growth factor-Binding Protein 8; KMD; IGF-Binding Protein 8; Cellular Communication N
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P78104
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CCN2; CCN Family Member 2; Prev. CTGF; IBP-8; IGFBP8; SEMDLSL; connective tissue growth factor; IGFBP-8; Hypertrophic Chondrocyte-Specific Protein 24; NOV2; Insulin-Like growth factor-Binding Protein 8; KMD; IGF-Binding Protein 8; Cellular Communication N
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P86582
Synonyms: connective tissue growth factor; CCN family member 2; Hypertrophic chondrocyte-specific protein 24; Insulin-like growth factor-binding protein 8; IBP-8; IGF-binding protein 8; IGFBP-8;

Host:  

Rabbit

Application:  

WB, IP, ELISA

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P81103
Synonyms: CCN 2; CCN-2; CCN2; connective tissue growth factor; Hcs 24; Hcs24; Hypertrophic chondrocyte specific protein 24; Hypertrophic chondrocyte-specific gene product 24; Insulin-like growth factor-Binding Protein 8; MGC102839; NOV 2; NOV2; connective tissue growth factor; CCN family member 2; Hypertrophic chondrocyte-specific protein 24; Insulin-like growth-binding protein 8; IBP-8; IGF-binding protein 8; IGFBP8; IGFBP-8; connective tissue growth factor precursor; CTGF_HUMAN.

Host:  

Rabbit

Application:  

WB, ELISA

Reactivity:  

Mouse, Rat

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Cat. No.: HY-P704310
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CCN2; CCN Family Member 2; Prev. CTGF; IBP-8; IGFBP8; SEMDLSL; connective tissue growth factor; IGFBP-8; Hypertrophic Chondrocyte-Specific Protein 24; NOV2; Insulin-Like growth factor-Binding Protein 8; KMD; IGF-Binding Protein 8; Cellular Communication N
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P79369
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCN2; CCN Family Member 2; Prev. CTGF; IBP-8; IGFBP8; SEMDLSL; connective tissue growth factor; IGFBP-8; Hypertrophic Chondrocyte-Specific Protein 24; NOV2; Insulin-Like growth factor-Binding Protein 8; KMD; IGF-Binding Protein 8; Cellular Communication N
Species:  
Rat
Source:  
HEK293
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Cat. No.: HY-P991950

Target:  

TGF-beta/Smad

Research Areas:  

Inflammation/Immunology

SHR-1906 is a selective fully humanized monoclonal IgG1 inhibitory antibody targeting CTGF. SHR-1906 specifically binds to CTGF, thereby blocking the interaction between CTGF and TGF-B1 with an inhibition rate of 55%. SHR-1906increases the survival rate in a pulmonary fibrosis model by reducing TGF-β1 levels and inhibiting fibrotic lesions in lung tissue in Bleomycin (HY-108345)-induced pulmonary fibrosis.SHR-1906 can be used for pulmonary fibrosis (IPF) research. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001) .
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Cat. No.: HY-P78713
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CCN2; CCN Family Member 2; Prev. CTGF; IBP-8; IGFBP8; SEMDLSL; connective tissue growth factor; IGFBP-8; Hypertrophic Chondrocyte-Specific Protein 24; NOV2; Insulin-Like growth factor-Binding Protein 8; KMD; IGF-Binding Protein 8; Cellular Communication N
Species:  
Rhesus Macaque
Source:  
HEK293
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Cat. No.: HY-P700701
Purity:  ≥ 90%, as determined by reducing Bis-Tris PAGE.
Synonyms: CCN2; CCN Family Member 2; Prev. CTGF; IBP-8; IGFBP8; SEMDLSL; connective tissue growth factor; IGFBP-8; Hypertrophic Chondrocyte-Specific Protein 24; NOV2; Insulin-Like growth factor-Binding Protein 8; KMD; IGF-Binding Protein 8; Cellular Communication N
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P704517
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCN5; connective tissue growth factor-Related Protein 58; Prev. WISP2; WNT1 Inducible Signaling Pathway Protein 2; CTGF-L; CCN Family Member 5; CT58; WNT1-Inducible-Signaling Pathway Protein 2; WISP-2; CTGFL; Cellular Communication Network factor 5; Conne
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P7268
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PPBP; Macrophage-Derived growth factor; Prev. THBGB1; C-X-C Motif Chemokine 7; SCYB7; Beta-Thromboglobulin; CTAP3; NAP-2-L1; CXCL7; Small Inducible Cytokine Subfamily B, Member 7; MDGF; Neutrophil-Activating Peptide-2; LDGF; Low-Affinity Platelet factor IV; TGB1; Neutrophil-Activating Peptide 2; PBP; Small Inducible Cytokine B7; Platelet Basic Protein; Small-Inducible Cytokine B7; Beta-TG; Thromboglobulin, Beta-1; CTAPIII; CXC Chemokine Ligand 7; LA-PF4; Thrombocidin 1; B-TG1; Thrombocidin 2; NAP-2; CTAP-III; TGB; THBGB; connective tissue-Activating Peptide III; TC1; Chemokine (C-X-C Motif) Ligand 7; TC2; Pro-Platelet Basic Protein; Leukocyte-Derived growth factor
Species:  
Human
Source:  
E. coli
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