cultures

Exosomes are small membrane vesicles of endocytic origin that are secreted by most cells in culture. Exosomes contain nucleic acids, proteins, lipids, amino acids, and metabolites, etc. Their diverse constituents can reflect their cell of origin. Exosomes are associated with immune responses, viral pathogenicity, pregnancy, cardiovascular diseases, central nervous system-related diseases, and cancer progression. Proteins, metabolites, and nucleic acids delivered by exosomes into recipient cells effectively alter their biological response. Such exosome-mediated responses can be disease promoting or restraining.

The biology of exosomes in disease is still emerging, and the number of studies addressing their utility in the diagnosis and treatment of various pathologies has increased substantially. MCE supplies a unique collection of 53 compounds with the activity of inhibiting or stimulating exsomes secretion/biosynthesis. MCE Exosomes Compound Library is a useful tool for exsomes research.

MCE Human iPSC-Derived Brain Organoid Long-term Culture Medium is a specialized culture system developed through systematic reformulation and concentration optimization based on neuronal cell culture platforms. It significantly enhances the adaptability and stability of long-term culture for brain organoids derived from human induced pluripotent stem cells (iPSCs).

MCE ITS Supplement (100×) can be used as a cell culture supplement and added to the medium for serum-free or low-serum cell culture systems.

MCE Mouse Intestinal Organoid Plus Kit is an upgraded serum-free culture system developed based on the Mouse Small Intestinal Organoid Culture Kit (HY-K6119), designed for the establishment, expansion, and long-term maintenance of mouse small intestinal organoids. The kit contains basal culture medium and multiple essential supplements, and an optional Wnt ligand supplement is provided to enable modulation of Wnt signaling activity in the culture system.

MCE Human Brain (Differentiation) Organoid Kit includes a basic culture medium and differentiation supplements, designed for the induction and culture of human brain organoids (hFBs).

MCE Basement Membrane Matrix for Organoid Culture is primarily composed of natural basement membrane matrix extracted from mouse tumors. This product is mainly used for organoid culture.

MCE Human Endometrium Organoid Kit includes a basic culture medium for human endometrium organoids, as well as culture supplements, and is designed for the effective construction of human endometrium organoids.

MCE Mouse Fetal Brain (Differentiation) Organoid Kit includes a basic culture medium and differentiation supplements, designed for the induction and culture of mouse fetal brain organoids (mFBs).

Minimum Essential Medium (MEM), also known as Minimal Essential Medium, was developed by Harry Eagle based on Eagle’s Basal Medium (BME). It is a basic cell culture medium with a simple formulation and broad applicability, and is one of the most commonly used media in animal cell culture. MEM contains only 12 essential amino acids, L-glutamine, and 8 vitamins. It is primarily used for the culture of adherent cells. With appropriate formulation modifications, it can also be used for other types of cell culture.

MCE Human Ovarian Cancer Organoid Kit includes a basic culture medium for ovarian cancer organoids, as well as culture supplements, and is designed for the effective construction of human ovarian cancer organoids.

MCE Human Neuroendocrine Neoplasm Organoid Kit includes a basic culture medium for Neuroendocrine Neoplasm organoids, as well as culture supplements, and is designed for the effective construction of human Neuroendocrine Neoplasm organoids.

MCE Human Kidney Cancer Organoid Kit includes a basic culture medium for Kidney Cancer organoids, as well as culture supplements, and is designed for the effective construction of human Kidney Cancer organoids.

MCE Human Esophageal Organoid Kit includes a basic culture medium for human esophageal organoids, as well as culture supplements, and is designed for the establishment and long-term maintenance of human esophageal organoids.

MCE Human Nasopharyngeal Carcinoma Organoid Kit includes a basic culture medium for Nasopharyngeal Carcinoma organoids, as well as culture supplements, and is designed for the effective construction of human Nasopharyngeal Carcinoma organoids.

MCE Lipid Concentrate (Chemically Defined) is a concentrated lipid solution with a clearly defined chemical composition, which can be added to cell culture media as an additive for serum-free or low-serum cell culture systems.

MCE Human Oral Squamous Carcinoma Organoid Kit includes a basic culture medium for Oral Squamous Carcinoma organoids, as well as culture supplements, and is designed for the effective construction of human Oral Squamous Carcinoma organoids.

MCE Human Mammary Epithelial Organoid Kit includes a basic culture medium for human Mammary Epithelial organoids, as well as culture supplements, and is designed for the establishment and long-term maintenance of human Mammary Epithelial organoids.

MCE Human Salivary Gland Cancer Organoid Kit includes a basic culture medium for Salivary Gland Cancer organoids, as well as culture supplements, and is designed for the effective construction of human Salivary Gland Cancer organoids.

MCE Human Airway Organoid Kit includes a basic culture medium for Human Airway organoids, as well as culture supplements, and is designed for the effective construction of human airway organoids (hAOs) from human airway stem cells.

MCE Mouse Airway Organoid Kit includes a basic culture medium for Mouse Airway organoids, as well as culture supplements, and is designed for the establishment and long-term maintenance of mouse airway organoids derived from airway stem cells.

MCE D-Glucose Solution (200 g/L) can be used as a serum-free supplement for cell culture media and is suitable for a variety of culture systems, including but not limited to DMEM, RPMI 1640, DMEM/F-12, IMDM, and MEM.

MCE Human Liver Ductal (Differentiation) Organoid Kit includes a basic culture medium for Human Liver Ductal (Differentiation) organoids, as well as culture supplements, and is designed for the establishment and long-term maintenance of human liver ductal organoids (hLDs) derived from adult stem cells.

MCE Mouse Liver Ductal (Differentiation) Organoid Kit includes a basic culture medium for Mouse Liver Ductal (Differentiation) organoids, as well as culture supplements, and is designed for the establishment and long-term maintenance of mouse liver ductal organoids (mLDs) derived from adult stem cells.

MCE Human Breast Cancer Organoid Complete Culture Medium is a pre-mixed, ready-to-use formulation composed of a basal breast cancer organoid medium and multiple key culture supplements at optimized ratios. This medium requires no additional preparation and enables the efficient and stable establishment of human breast cancer organoid models.

MCE Human Colorectal Cancer Organoid Complete Culture Medium is a pre-mixed, ready-to-use formulation composed of a basal colorectal cancer organoid medium and multiple key culture supplements at optimized ratios. This medium requires no additional preparation and enables the efficient and stable establishment of human colorectal cancer organoid models.

MCE Human Gastric Cancer Organoid Complete Culture Medium is a pre-mixed, ready-to-use formulation composed of a basal gastric cancer organoid medium and multiple key culture supplements at optimized ratios. This medium requires no additional preparation and enables the efficient and stable establishment of human gastric cancer organoid models.

MCE Human Ovarian Cancer Organoid Complete Culture Medium is a pre-mixed, ready-to-use formulation composed of a basal ovarian cancer organoid medium and multiple key culture supplements at optimized ratios. This medium requires no additional preparation and enables the efficient and stable establishment of human ovarian cancer organoid models.

MCE Human PSC Embryoid Body (EB) Induction Medium is specifically designed to support the efficient and reproducible formation of uniform embryoid bodies from pluripotent stem cells under suspension culture conditions. This optimized culture system integrates microenvironmental regulation with metabolic adaptation strategies, significantly improving the stability and reproducibility of EB formation.

MCE N-2 Serum-free Supplement (100×) can be used in conjunction with growth factors such as bFGF and EGF in serum-free neuronal cell culture mediums, DMEM and the DMEM/F12. This product is formulated with basal culture medium. The 5 mL is defined as the base specification. All larger sizes correspond to incremental volumes of this base.

MCE Exosome-Specific Culture Medium (Serum-Free, Phenol Red-Free) is specifically formulated for optimized exosome collection.

MCE Human Neuroblastoma Cell Culture Medium is specially designed to promote the in vitro growth of primary human neuroblastoma cells.

MCE Organoid Anti-Adhesion Rinsing Solution is specifically formulated to prevent non-specific cell adhesion in cell culture applications.

MCE Human Brain Organoid (Expansion) Kit contains Human Brain Organoid Expansion Basal Medium and Human Brain Organoid Expansion Culture Supplements. This kit enables the efficient in vitro generation of human forebrain organoids (hFBs). Within this culture system, human brain tissue can spontaneously form organoid structures that faithfully recapitulate key features of in vivo cellular heterogeneity and complex tissue organization.

MCE Advanced DMEM/F-12 is an optimized mammalian cell culture medium designed to reduce the requirement for fetal bovine serum (FBS). Compared with classical DMEM/F-12 medium, it can reduce serum usage by 50–90% while maintaining comparable cell growth rates and cellular morphology, thereby effectively lowering serum consumption and reducing overall cell culture costs.

Ham’s F-12K Medium was originally designed for the culture of primary human hepatocytes and differentiated rat and chicken cells. It is particularly suitable for single-cell cloning of Chinese hamster ovary (CHO) cells under serum-free conditions. When supplemented with serum, it can also be used for the culture of various other mammalian cell types, including chondrocytes and rat prostate epithelial cells.

MCE Neuroblastoma Organoid Kit contains Neuroblastoma organoid basal medium and culture supplement. This product can be used to efficiently construct Neuroblastoma organoid.

MCE Rhabdomyosarcoma Organoid Kit contains rhabdomyosarcoma organoid basal medium and culture supplement. This product can be used to efficiently construct rhabdomyosarcoma organoid.

MCE Hepatoblastoma Organoid Kit contains hepatoblastoma organoid basal medium and culture supplement. This product can be used to efficiently construct hepatoblastoma organoid.

MCE Human Acute Myeloid Leukemia Cell Culture Medium is specially designed to promote the in vitro growth of primary human acute myeloid leukemia cells.

MCE Mouse Fetal Brain Organoid (Expansion) Kit contains Mouse Fetal Brain Organoid Expansion Basal Medium and Mouse Fetal Brain Organoid Expansion Culture Supplement . This kit enables the efficient in vitro generation of mouse fetal brain organoids (mFBs). Within this culture system, mouse fetal brain tissue can spontaneously form organoid structures that faithfully recapitulate key features of in vivo cellular heterogeneity and complex tissue organization.

MCE Bi-27 Serum-free Supplement (50×), Antioxidant-Free is a customized neuronal culture supplement developed by removing antioxidants components (such as vitamins, superoxide dismutase, catalase, etc.) from the standard Bi-27 formulation. It is specifically designed for investigating the roles of reactive oxygen species (ROS) in aging, cytotoxicity, apoptosis, and chronic neurological diseases. This formulation provides a stable culture environment for mechanistic studies without the interference of exogenous antioxidants.

MCE Human iPSC/ESC Cortical Brain Organoid Maturation Medium is a ready-to-use culture system specifically formulated for the long-term maintenance and maturation of cortical brain organoids. It serves as a seamless transition from the induction phase and supports the continued growth and functional development of the organoids. Upon switching PSC-derived cortical brain organoids to this medium, organoid viability and structural stability are markedly enhanced, enabling a robust and extended culture period of up to 180 d.

MCE Protein A Plus Magnetic Agarose Beads can be used for the detection and purification of IgG from serum, ascites fluid, cell culture supernatant and other antibody samples.

MCE Brain Glioma Organoid Kit contains brain glioma organoid basal medium and culture supplement. This product can be used to efficiently construct brain glioma organoid.

MCE T-Cell Expansion Medium (Serum-Free) is a specialized culture medium formulated for the in vitro cultivation and robust expansion of human T lymphocytes without the need for serum.

MCE Protein G Plus Magnetic Agarose Beads can be used for the detection and purification of IgG from serum, ascites fluid, cell culture supernatant and other antibody samples.

MCE BM-Cyclin mainly contains Tiamulin fumarate and Minocycline hydrochloride, can effectively inhibit and remove mycoplasma contamination widespread in cell cultures. It is also effective against some common bacteria.

MCE Basement Membrane Matrix IPSC-qualified is primarily composed of natural basement membrane matrix extracted from mouse tumors. This product is mainly used for stem cells culture.

MCE Renilla-Firefly Luciferase Dual Assay Kit is designed to be used for high-throughput, rapid quantitation of both Firefly and Renilla luciferases from a single sample in mammalian cell culture.

MCE Basement Membrane Matrix (Phenol Red) is primarily composed of a natural basement membrane matrix derived from mouse tumors. This product is mainly for studies of tumor invasion, angiogenesis, and organoid culture.

MCE Human Bladder Cancer Organoid Kit contains human bladder cancer organoid basal medium and culture supplement. This product can be used to efficiently construct Human Bladder Cancer organoid.