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deliver

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211

Inhibitors & Agonists

3

Screening Libraries

4

Fluorescent Dye

48

Biochemical Assay Reagents

37

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9

Inhibitory Antibodies

2

Natural
Products

3

Isotope-Labeled Compounds

2

Click Chemistry

69

Oligonucleotides

2

GMP Molecules

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-134541
    SM-102
    Maximum Cited Publications
    45 Publications Verification

    Liposome Infection
    SM-102 is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 has higher transfection efficiency. SM-102 plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines .
    SM-102
  • HY-130751
    DODAP
    1 Publications Verification

    Liposome Inflammation/Immunology
    DODAP is a cationic lipid utilized as the lipid component in liposomes (pKa = 5.59 in TNS binding tests). DODAP is employed for encapsulating siRNA and delivering immunostimulated chemotherapeutic agents both in vitro and in vivo. DODAP holds great promise for research in vaccines and inflammation .
    DODAP
  • HY-B0572
    Zinc Pyrithione
    10+ Cited Publications

    Environmental Pollutants Bacterial Cuproptosis Proton Pump Fungal Infection Metabolic Disease
    Zinc Pyrithione is an antifungal and antibacterial agent disrupting membrane transport by blocking the proton pump . Zinc Pyrithione is also a copper ionophore that delivers copper into cells and is a useful tool for studying cuproptosis .
    Zinc Pyrithione
  • HY-134781
    CKK-E12
    4 Publications Verification

    Liposome Others
    CKK-E12 is a ionizable lipid in combination with other lipids make up the lipid nanoparticles which are used to deliver RNA-based research. CKK-E12 is highly selective toward liver parenchymal cell in vivo,
    CKK-E12
  • HY-15729
    Rociletinib
    10+ Cited Publications

    CO-1686; AVL-301; CNX-419

    EGFR Cancer
    Rociletinib (CO-1686) is an orally delivered kinase inhibitor that specifically targets the mutant forms of EGFR including T790M, and the Ki values for EGFRL858R/T790M and EGFRWT are 21.5 nM and 303.3 nM, respectively.
    Rociletinib
  • HY-141126

    Biochemical Assay Reagents Cancer
    Azido-PEG4-alpha-D-mannose is a PEG linker that combines an azide group with an alpha-D-mannose moiety. Azido-PEG4-alpha-D-mannose is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Azido-PEG4-alpha-D-mannose has the targeting property of mannose, which can accurately deliver drugs to specific cells or tissues to improve the therapeutic effect of drugs .
    Azido-PEG4-alpha-D-mannose
  • HY-13055A
    Telotristat ethyl
    4 Publications Verification

    LX1032; LX1606

    Tryptophan Hydroxylase Neurological Disease Cancer
    Telotristat ethyl (LX1032) is a novel, orally-delivered inhibitor of tryptophan hydroxylase that reduces serotonin production.
    Telotristat ethyl
  • HY-13055
    Telotristat etiprate
    4 Publications Verification

    LX1606 Hippurate

    Tryptophan Hydroxylase Neurological Disease Cancer
    Telotristat etiprate (LX1606 Hippurate) is a novel, orally-delivered inhibitor of tryptophan hydroxylase that reduces serotonin production.
    Telotristat etiprate
  • HY-111606

    Ligands for Target Protein for PROTAC Cancer
    DUPA, belongs to a class of glutamate ureas, is used as the targeting moiety in agent conjugate to selectively deliver cytotoxic agents to prostate cancer cells .
    DUPA
  • HY-108932

    Gemcitabine 5′-phosphate

    Apoptosis Cancer
    Gemcitabine monophosphate (Gemcitabine 5′-phosphate) is one of the active intermediates of Gemcitabine (HY-17026). Gemcitabine monophosphate has a synergistic anti-cancer effect and can be delivered by formulating it into nanoparticles .
    Gemcitabine monophosphate
  • HY-46759

    Liposome Infection
    Genevant CL1 is an ionizable lipid (pKa = 6.3) suitable for the preparation of lipid nanoparticles (LNPs) for delivering nucleic acid payloads and intramuscular vaccines. Genevant CL1 is a component of lipid nanoparticle delivery systems for mRNA vaccines .
    Genevant CL1
  • HY-139305
    CL4H6
    1 Publications Verification

    Liposome Cancer
    CL4H6 is a pH-sensitive cationic lipid. CL4H6 is the main component of lipid nanoparticles (LNPs), which can be used to target and deliver siRNA, and induces a potent gene-silencing response .
    CL4H6
  • HY-138962

    K-Carrageenan Karra Type

    Apoptosis Inflammation/Immunology Cancer
    κ-Carrageenan is a natural polymer which predominantly available in red seaweeds. κ-Carrageenan is an effective agent carrier to deliver curcumin in cancer cells and to induce apoptosis. κ-carrageenan serves as a potential inflammatory agent that magnifies existing intestinal inflammation .
    κ-Carrageenan
  • HY-139306

    Liposome Inflammation/Immunology
    BAMEAO16B is a lipid nanoparticle. BAMEAO16B integrated with disulfide bonds, can efficiently deliver Cas9 mRNA and sgRNA into cells while releasing RNA in response to the reductive intracellular environment for genome editing. BAMEAO16B can be used for the research of gene editing .
    BAMEA-O16B
  • HY-142983

    Dimyristoylphosphatidylethanolamine; 1,2-Ditetradecyl-rac-glycero-3-phosphoethanolamine

    Liposome Others
    DMPE is the dimyristoylphosphatidylcholine. DMPE is a liposome used to deliver agents .
    DMPE
  • HY-103591
    DUPA(OtBu)-OH
    1 Publications Verification

    PSMA Cancer
    DUPA(OtBu)-OH is a DUPA precursor. DUPA is used as the targeting moiety to actively deliver Docetaxel (DTX) for treatment of Prostate-Specific Membrane Antigen (PSMA) expressing prostate cancer.
    DUPA(OtBu)-OH
  • HY-P1491

    HIV Infection
    HIV-1 TAT (48-60) is a cell-penetrating peptide derived from the human immunodeficient virus (HIV)-1 Tat protein residue 48-60. It has been used to deliver exogenous macromolecules into cells in a non-disruptive way.
    HIV-1 TAT (48-60)
  • HY-116016

    L-DOPA ethyl ester; Levodopa ethyl ester

    Dopamine Receptor Drug Metabolite Neurological Disease
    Etilevodopa (L-Dopa ethyl ester), an ethyl-ester proagent of Levodopa, is rapidly hydrolyzed to Levodopa and ethanol by nonspecific esterases in the gastrointestinal tract. Etilevodopa is used for the treatment of Parkinson disease (PD). Levodopa is the direct precursor of dopamine and is a suitable proagent as it facilitates CNS penetration and delivers dopamine .
    Etilevodopa
  • HY-132587A

    ALN-AT3SC sodium; SAR439774 sodium

    Factor Xa Small Interfering RNA (siRNA) Thrombin Cardiovascular Disease
    Fitusiran (ALN-AT3SC) sodium is a siRNA strategy. Fitusiran delivers siRNA targeting the SERPINC1 gene in hepatocytes to inhibit antithrombin synthesis. Fitusiran sodium enhances thrombin activity and increases Thrombin generation, thereby restoring hemostatic function. Fitusiran sodium can be used in hemophilia-related research .
    Fitusiran sodium
  • HY-156857

    Liposome Inflammation/Immunology Cancer
    PPZ-A10 is an ionizable cationic lipid. PPZ-A10 preferentially delivers mRNA to liver and spleen immune cells. Pi-LNPs containing PPZ-A10 can effectively deliver mRNA/siRNA to solid tumors .
    PPZ-A10
  • HY-P3432

    Biochemical Assay Reagents Others
    DfTat is a dimer of the prototypical cell-penetrating peptide TAT. DfTat can deliver small molecules, peptides and proteins into live cells with a particularly high efficiency. DfTat labeled with the rhodamine can be used as a tracer for easy detection .
    DfTat
  • HY-156174

    Toll-like Receptor (TLR) ADC Payload Cancer
    E104 (compound 1) is a potent and selective TLR7 agonist. E104 can be delivered by antibody-drug conjugate (ADC) technology to elicit potent anticancer activity. E104 induces the activation of mouse macrophages and hPBMCs .
    E104
  • HY-15729A
    Rociletinib hydrobromide
    10+ Cited Publications

    CO-1686 hydrobromide; AVL-301 hydrobromide; CNX-419 hydrobromide

    EGFR Cancer
    Rociletinib hydrobromide (CO-1686 hydrobromide) is an orally delivered kinase inhibitor that specifically targets the mutant forms of EGFR including T790M, and the Ki values for EGFRL858R/T790M and EGFRWT are 21.5 nM and 303.3 nM, respectively.
    Rociletinib hydrobromide
  • HY-128775

    Drug Derivative Cancer
    JHU395 is an orally-bioavailable and a plasma stable lipophilic glutamine antagonists (GA) proagent. JHU395 delivers 6-diazo-5-oxo-L-norleucine (DON) to malignant peripheral nerve sheath tumor (MPNST) in vitro and in vivo, and has antitumor activity in MPNST .
    JHU395
  • HY-147102

    LYTACs Metabolic Disease
    tri-GalNAc biotin is a biotinylated ASGPR (Asialoglycoprotein receptor) ligand. tri-GalNAc biotin promotes cellular uptake of neutravidin (NA) via ASGPR. tri-GalNAc biotin delivers neutravidin to lysosomes for degradation. tri-GalNAc biotin can be used for research of LYsosome TArgeting Chimera (LYTAC) .
    tri-GalNAc biotin
  • HY-P99566

    ST2146

    Transmembrane Glycoprotein Cancer
    Tenatumomab (ST2146) is a murine monoclonal antibody against tenascin-C. And tenascin-C, the large extracellular glycoprotein, is overexpressed in cancer. Tenatumomab has been used for Pretargeted Antibody Guided Radioimmunoresearch (PAGRIT), and delivering radionuclides to tumors via PAGRIT and direct 131Iodine labeling approach .
    Tenatumomab
  • HY-153377

    Liposome SARS-CoV Bacterial Infection Inflammation/Immunology
    Lipid 14 is an ionizable amino lipid. Lipid 14 delivers mRNA into target cells, significantly enhancing the in vivo expression efficiency and immunogenicity of mRNA. Lipid 14 can be used to synthesize lipid nanoparticles (LNPs). Lipid 14 can be used for studies of SARS-CoV-2 and Yersinia pestis .
    Lipid 14
  • HY-159854

    Liposome Cancer
    C14-O2 is an ionizable cationic lipid that can be used to synthesize lipid nanoparticles (LNP) for delivering mRNA and other payloads .
    C14-O2
  • HY-156829A

    Biochemical Assay Reagents Cancer
    PLGA-PEG-PLGA (1500-1500-1500) (LA/GA 15:1) is a matrix materia, with lactic acid (LA):glycolic acid (GA) = 15:1, that acts as anti-cancer drug delivery. PLGA-PEG-PLGA (1500-1500-1500) (LA/GA 15:1) can improve a drug's bioavailability, efficacy, water solubility, drug encapsulation efficiency, sustained drug release, and to minimize undesirable toxicity .
    PLGA-PEG-PLGA (1500-1500-1500) (LA/GA 15:1)
  • HY-P2500

    Fluorescent Dye Others
    (Arg)9, FAM-labeled, a cell-penetrating peptide (CPP), is a nona-arginine (ARG) with FAM label. CPPs have emerged as powerful tools for delivering bioactive cargoes into the cytosol of intact cells .
    (Arg)9, FAM-labeled
  • HY-P10991A

    Stearylated octaarginine TFA

    Biochemical Assay Reagents Others
    Stearyl-(homoarginine)8 (Stearylated octaarginine) TFA is an effective gene delivery vector that can deliver plasmid DNA into cells. Stearyl-(homoarginine)8 TFA can make plasmid DNA more effectively internalized into cells and improve the nuclear delivery rate .
    Stearyl-(homoarginine)8 TFA
  • HY-137501

    Liposome Others
    306-O12B-3 is a lipidoid that can efficiently deliver ASO both in vitro and in vivo. 306-O12B-3 is used to transport small molecule drugs across the blood-brain barrier (BBB) .
    306-O12B-3
  • HY-P4119

    Biochemical Assay Reagents Others
    Pep-1-Cysteamine is an amphipathic chimeric cell-penetrating peptide. Pep-1-Cysteamine can penetrate biological membranes in an energy-independent manner without forming transmembrane pores, and efficiently deliver active proteins into cells, with its translocation dominated by electrostatic interactions and membrane perturbation .
    Pep-1-Cysteamine
  • HY-159858

    Liposome Cancer
    Lipid 16 is an ionizable lipid that can be used to synthesize lipid nanoparticles (LNP) for delivering mRNA and other payloads. Lipid 16 as a potent cell type-specific ionizable lipid for the CD11bhi macrophage population without an additional targeting moiety .
    Lipid 16
  • HY-156829

    Biochemical Assay Reagents Cancer
    PLGA-PEG-PLGA (1500-1500-1500) (LA/GA 1:1) is a matrix materia, with lactic acid (LA):glycolic acid (GA) = 1:1, that acts as anti-cancer drug delivery. PLGA-PEG-PLGA (1500-1500-1500) (LA/GA 1:1) can improve a drug's bioavailability, efficacy, water solubility, drug encapsulation efficiency, sustained drug release, and to minimize undesirable toxicity .
    PLGA-PEG-PLGA (1500-1500-1500) (LA/GA 1:1)
  • HY-108045

    Phosphodiesterase (PDE) Endocrinology
    Lodenafil carbonate, a dimer that acts as a proagent delivering Lodenafil in vivo, is an orally active phosphodiesterase type 5 (PDE5) inhibitor for the treatment of erectile dysfunction (ED) .
    Lodenafil carbonate
  • HY-156936

    Liposome Others
    RCB-02-4-8 is an ionizable cationic lipid that is used to form lipid nanoparticles (LNPs) to deliver mRNA. RCB-02-4-8 can improve the efficiency of lung transfection in mice .
    RCB-02-4-8
  • HY-W440834

    Liposome Others
    DSPE-PEG5000-azide is a click chemistry reactive phospholipid polyPEG which forms lipid bilayer or micelles in an aqueous solution. The polymer can be used to prepare liposomes or nanoparticles used for delivering nutrients or therapeutic agents, for example mRNA or DNA vaccine.
    DSPE-PEG5000-azide
  • HY-169838

    Biochemical Assay Reagents Others
    WYneC can specifically bind to sulfinylated proteins in living cells and then react with fluorescent probes containing azide groups for detection. In the field of redox biology, WYneC can also be used to determine the occupancy of S-sulfinylation sites or as a carrier to deliver substances to mitochondria .
    WYneC
  • HY-153137

    304O13

    Liposome Cancer
    Tri-N-tridecyl 3-(ethyl(methyl)amino)propanoate is a biodegradable lipid prepared by the conjugate addition of alkylamines to acrylates. Tri-N-tridecyl 3-(ethyl(methyl)amino)propanoate can be used in various drug delivery systems to deliver polynucleotides, siRNA for example .
    Tri-N-tridecyl 3-(ethyl(methyl)amino)propanoate
  • HY-159865

    Liposome Others
    CL15F6 is an ionizable lipid that can be used to synthesize lipid nanoparticles (LNP) for delivering mRNA and other payloads .
    CL15F6
  • HY-159856

    Diphosphatidylglycerol (16:0)

    Liposome Others
    16:0 Cardiolipin (Diphosphatidylglycerol (16:0)) is a phospholipid derived from Palmitic acid (16:0) that can be used to synthesize lipid nanoparticles (LNP) for delivering mRNA and other payloads .
    16:0 Cardiolipin
  • HY-143688

    Liposome Others
    EDMPC, a cationic lipid, has an enhanced ability to deliver DNA to pulmonary tissues. EDMPC mediates intralobar DNA delivery to rodents .
    EDMPC
  • HY-W019682

    Biochemical Assay Reagents Cancer
    Fmoc-FF is a building block. Fmoc-FF-prepared hydrogels and nanogels selectively deliver Dexamethasone (HY-14648) to leukemia cells .
    Fmoc-FF
  • HY-108932A

    Gemcitabine 5′-phosphate disodium

    Apoptosis Cancer
    Gemcitabine monophosphate (Gemcitabine 5′-phosphate) is one of the active intermediates of Gemcitabine (HY-17026). Gemcitabine monophosphate has a synergistic anti-cancer effect and can be delivered by formulating it into nanoparticles .
    Gemcitabine monophosphate disodium
  • HY-153737

    Liposome Others
    113-N16B is an ionizable cationic lipid used for the generation of lipid nanoparticles (LNPs). 113-N16B delivers mRNA preferentially to pulmonary endothelial cells.
    113-N16B
  • HY-A0081S

    Dopamine Receptor Neurological Disease Cancer
    Fluphenazine-d8 (dihydrochloride) is the deuterium labeled Fluphenazine dihydrochloride. Fluphenazine dihydrochloride is a phenothiazine-class D1DR and D2DR inhibitor; used to deliver Fluphenazine to biological systems in studies probing the effects and metabolic fates of this commonly used dopamine antagonist.
    Fluphenazine-d8 dihydrochloride
  • HY-P3497A

    Amino Acid Derivatives Others
    Fmoc-Cys-Asp10 (TFA) is a non-releasable oligopeptide linker, involves in the synthesis of releasable oligopeptide linker. Releasable oligopeptide linker can be used to deliver agent to a bone fracture-homing oligopeptide and reduces fractured femur healing times .
    Fmoc-Cys-Asp10 TFA
  • HY-109174

    CPX-POM

    γ-secretase Metabolic Disease Cancer
    Fosciclopirox (CPX-POM) suppresses growth of urothelial cancer by targeting the γ-secretase complex. Fosciclopirox selectively delivers the active metabolite, Ciclopirox (CPX), to the entire urinary tract. Ciclopirox has anticancer activity in a number of solid and hematologic malignancies .
    Fosciclopirox
  • HY-P10991

    Stearylated octaarginine

    Biochemical Assay Reagents Others
    Stearyl-(homoarginine)8 (Stearylated octaarginine) is an effective gene delivery vector that can deliver plasmid DNA into cells. Stearyl-(homoarginine)8 can make plasmid DNA more effectively internalized into cells and improve the nuclear delivery rate .
    Stearyl-homoarginine8

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