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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
dihydrodiol
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "dihydrodiol" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-W012985
CAS No.: 600-22-6
Target:
Research Areas:
Methyl pyruvate is a p53/p21 axis inhibitor, intrinsic apoptosis inhibitor, cytotoxic agent, ATP production enhancer, proteasome function restorer, TDP-43 localization normalizer, ATP-sensitive potassium (K +ATP) channel inhibitor, depolarizer, and insulin secretagogue .Methyl pyruvate turns off apoptotic pathways, induces cancer cell death, acts as a substrate for dimeric dihydrodiol dehydrogenase, enhances TCA cycle activity, rescues proteasome impairment and TDP-43 mislocalization, inhibits K +ATP channels independent of ATP, depolarizes pancreatic β-cell membranes, modulates insulin secretion, and enters pancreatic β-cell mitochondria via a specific transporter .Methyl pyruvate can be used for the research of lung adenocarcinoma, ovarian clear cell adenocarcinoma, breast adenocarcinoma, amyotrophic lateral sclerosis, and type II diabetes .
Synonyms: PCI-45227
Dihydrodiol-Ibrutinib (PCI-45227) is a dihydrodiol active metabolite of Ibrutinib (HY-10997), has inhibitory activity towards BTK approximately 15 times lower than that of ibrutinib .
Cat. No.: HY-100659S
CAS No.: 2068022-09-1
Synonyms: PCI-45227-d5
Cat. No.: HY-E70418A
Target:
Research Areas:
Epoxide Hydrolase, Rhodococcus rhodochrous (EC 3.3.2.3), converts epoxides to trans-dihydrodiols, which can combine with other substances and be excreted from the body. Epoxides are products of the degradation of aromatic compounds.
Cat. No.: HY-P7469
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: AKR1C2; DD/BABP; Prev. DDH2; Aldo-Keto Reductase Family 1, Member C2 (dihydrodiol Dehydrogenase 2; Bile Acid Binding Protein; 3-Alpha Hydroxysteroid Dehydrogenase, Type III); Prev. TDD; dihydrodiol Dehydrogenase/Bile Acid-Binding Protein; DD2; Trans-1,2-D
Species:
Human
Source:
E. coli
Cat. No.: HY-P75520
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: AKR1C2; DD/BABP; Prev. DDH2; Aldo-Keto Reductase Family 1, Member C2 (dihydrodiol Dehydrogenase 2; Bile Acid Binding Protein; 3-Alpha Hydroxysteroid Dehydrogenase, Type III); Prev. TDD; dihydrodiol Dehydrogenase/Bile Acid-Binding Protein; DD2; Trans-1,2-D
Species:
Human
Source:
E. coli
Cat. No.: HY-P7470
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: AKR1C4; Chlordecone Reductase; Prev. CHDR; MGC22581; HAKRA; DD-4; DD4; Aldo-Keto Reductase Family 1, Member C4 (Chlordecone Reductase; 3-Alpha Hydroxysteroid Dehydrogenase, Type I; dihydrodiol Dehydrogenase 4); CDR; Chlordecone Reductase; 3-Alpha Hydroxys
Species:
Human
Source:
E. coli
Target:
Research Areas:
L-Lactaldehyde ((2S)-Hydroxypropanal) is a chiral aldehyde, metabolic intermediate, and enzyme substrate. L-Lactaldehyde is oxidized to L-lactate by NAD-dependent lactaldehyde dehydrogenase. L-Lactaldehyde is reduced to L-1,2-propanediol by NADH/NADPH-dependent oxidoreductases. L-Lactaldehyde is used in studies of microbial sugar metabolism and carbonyl metabolism .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
