1654820-87-7
1654820-87-7
Chemical Structure
Dihydrodiol-Ibrutinib
Synonym(s): PCI-45227
- CAS No.: 1654820-87-7
- Formula:C25H26N6O4
- Molecular Weight:474.51
IUPAC Name: 1-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-2,3-dihydroxypropan-1-one
InChIKey: NWKPMPRXJGMTKQ-DIAVIDTQSA-N
SMILES: O=C(N1C[C@H](N2N=C(C3=CC=C(OC4=CC=CC=C4)C=C3)C5=C(N)N=CN=C52)CCC1)C(O)CO
Biological Activity: Dihydrodiol-Ibrutinib (PCI-45227) is a dihydrodiol active metabolite of Ibrutinib (HY-10997), has inhibitory activity towards BTK approximately 15 times lower than that of ibrutinib[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Dihydrodiol-Ibrutinib | 99.91% | Dihydrodiol-Ibrutinib (PCI-45227) is a dihydrodiol active metabolite of Ibrutinib (HY-10997), has inhibitory activity towards BTK approximately 15 times lower than that of ibrutinib. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
Keywords
