1 Result for "

guanosine cofactor

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "guanosine cofactor" in MCE Product Catalog:

Cat. No.: HY-108190
CAS No.: 33103-21-8
Target:  

Antibiotic Bacterial

Research Areas:  

Infection

Tuberactinomycin A is a basic cyclic peptide antibiotic and a group I intron RNA splicing inhibitor, with an IC50 of 10 μM against the G-binding site of bacteriophage T4 group I intron RNA. Tuberactinomycin A exerts antibacterial effects by acting on the initiation and elongation steps of bacterial bacteria ribosomes to inhibit prokaryotic protein synthesis. Tuberactinomycin A competes with guanosine cofactors for binding to the G-binding site of group I intron RNA, forms electrostatic interactions with the RNA backbone, and inhibits the self-splicing of bacteriophage T4 td and sunY group I introns, and its inhibitory activity depends on Mg 2+ concentration. Tuberactinomycin A can be used in studies related to bacterial infections .
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