1 Result for "

hAChE-IN-5

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "hAChE-IN-5" in MCE Product Catalog:

Cat. No.: HY-155365
CAS No.: 3007667-15-1
Research Areas:  

Neurological Disease

hAChE-IN-5 (compound 49) is a potent hAChE and hBuChE inhibitor with IC50 values of 0.17 μM and 0.17 μM, respectively. hAChE-IN-5 shows potent GSK3β inhibition with an IC50 value of 0.21 μM. hAChE-IN-5 is used as tau protein aggregation and Aβ1-42 self-aggregation inhibitor. hAChE-IN-5 can bind virtually with the PAS affecting Aβ aggregation, thus preventing Aβ-dependent neurotoxicity. hAChE-IN-5 can penetrate BBB and has the potential for multi-targeted anti-Alzheimer's agents research .
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