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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
29 Results for "
human CA II
" in MedChemExpress (MCE) Product Catalog:
Products (29)
29 Results for "human CA II" in MCE Product Catalog:
5
5 Cited Publications
Cat. No.: HY-P0221
CAS No.: 137061-48-4
Synonyms: Pituitary Adenylate Cyclase Activating Polypeptide 38
Research Areas:
2
2 Cited Publications
Cat. No.: HY-N0515
CAS No.: 945619-74-9
1
1 Cited Publications
Cat. No.: HY-P78746
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CA2; CAC; CArbonic Anhydrase 2; Epididymis Secretory Protein Li 282; CArbonic Anhydrase II; Epididymis Luminal Protein 76; CA-II; CArbonic Anhydrase B; CArbonate Dehydratase II; CArbonic Dehydratase; Cyanamide Hydratase CA2; CArbonic Anhydrase; CAII; HEL-
Cat. No.: HY-N7575
CAS No.: 21973-23-9
Synonyms: LNFP II
Category:
Polysaccharides Disease markers Metabolic Disease Endogenous metabolite Disease Research Fields Saccharides Cancer
Target:
Cat. No.: HY-P1769
CAS No.: 34233-50-6
Target:
Research Areas:
Cat. No.: HY-W587805
CAS No.: 41997-13-1
Synonyms: FHxSA
Research Areas:
Perfluorohexane sulfonamide (FHxSA) is the inhibitor for carbonic anhydrase, that inhibits bovine CA and human CA II with IC50 of 0.122 and 1.38 μM. Perfluorohexane sulfonamide is a delayed-action insecticide, that can be used to control red fire ants (Solenopsis invicta). Perfluorohexane sulfonamide could be a environmental pollutant .
Cat. No.: HY-N0515R
CAS No.: 945619-74-9
Cat. No.: HY-P1792
CAS No.: 52580-29-7
Target:
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Cat. No.: HY-B0124S
CAS No.: 1020720-04-0
Cat. No.: HY-32933
CAS No.: 149104-90-5
Target:
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4-Acetylphenylboronic acid is a potent inhibitor of carbonic anhydrases II(CA II), with IC50s of 246 μM and 281.40 μM for bovine CA II (bCA II) and human CA II (hCA II). 4-Acetylphenylboronic acid can be obtained via mechanochemistry and solvent evaporation. 4-Acetylphenylboronic acid has a loss of the carbonyl group at 500-550 K .
Cat. No.: HY-161507
CAS No.: 3036136-18-9
Research Areas:
CAI/II-IN-8 (Compound 8) is a hydrazide derivative based on 4-hydroxybenzaldehyde. CAI/II-IN-8 primarily targets human carbonic anhydrase isomerase I (hCA I) and II (hCA II) for inhibition (IC50 = 21.35 ± 0.39 nM (CA I); 7.12 ± 0.12 nM (CA II)). CAI/II-IN-8 inhibits AChE and BChE as well(IC50 = 46.27 ±0.75 nM (AChE); 43.38 ± 0.83 nM (BChE)). . .
Cat. No.: HY-174835
Target:
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hCA-I/hCA-II-IN-1 (Compound P4) is a potent dual human carbonic anhydrase I (hCA-I) and human carbonic anhydrase II (hCA-II) inhibitor with Ki values of 0.22 μM and 0.33 μM, respectively. hCA-I/hCA-II-IN-1 can be used in research on diseases related to CA enzymes such as glaucoma, hypertension, and ulcers .
Cat. No.: HY-178030
Research Areas:
CAXII-IN-3 is an effective carbonic anhydrase (CA XII) inhibitor with a Ki of 53 nM. CAXII-IN-3 exhibits selective inhibition against multiple human CA subtypes with Kis of 5.3 μM, 75 nM, 1.9 μM, > 10 μM against CA I, CA II, CA IV and CA IX. CAXII-IN-3 mainly inhibits CA II and XII, and reduces aqueous humor production. CAXII-IN-3 exhibits β3-AR agonistic activity, can dilate retinal blood vessels, and improve optic nerve perfusion. CAXII-IN-3 can be used in the research of ocular disorders such as glaucoma .
Cat. No.: HY-P1792A
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Cat. No.: HY-151472
CAS No.: 3031666-31-3
Target:
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hCAIX/XII-IN-6 is an orally active carbonic anhydrase (CA) inhibitor. hCAIX/XII-IN-6 inhibits human CA isoforms hCA I, II, IV, IX, and XII with Ki values of 6697 nM, 2950 nM, 4093 nM, 4.1 nM and 7.7 nM, respectively. hCAIX/XII-IN-6 can be used for the research of rheumatoid arthritis (RA) .
Cat. No.: HY-12155
CAS No.: 877316-38-6
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JNJ-26990990 is a broad-spectrum antiepileptic agent with oral activity. JNJ-26990990 can inhibit voltage-gated Na + channels and N-type Ca 2+ channels, but has a very weak inhibitory effect on human carbonic anhydrase-II (IC50 = 110 μM) .
Cat. No.: HY-156181
CAS No.: 59994-64-8
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Research Areas:
hCAIX/XII-IN-8 (compound 3g) is a potent human (carbonic anhydrase) CA IX and XII inhibitor, with Ki values of 8.5 and 6.7 nM, respectively. hCAIX/XII-IN-8 shows particularly strong inhibitory activity against the tumor-associated membrane-bound isoforms, hCA IX and XII, while maintaining a high selectivity ratio over cytosolic off-target isoforms hCA I and II .
Cat. No.: HY-P0221A
Synonyms: Pituitary Adenylate Cyclase Activating Polypeptide 38 TFA
Research Areas:
Cat. No.: HY-113038AR
CAS No.: 40951-21-1
Synonyms: 2-Hydroxyglutarate disodium (Standard); 2-Hydroxyglutaric acid disodium (Standard); 2-Hydroxypentanedioic acid disodium (Standard)
Target:
Research Areas:
Methyl acetazolamide (Propazolamide) is a carbonic anhydrase inhibitor with Ki values of 37.5 nM against Enterococcus faecium α-CA, 250.1 nM against Enterococcus faecium γ-CA, 235.4 nM against human CA I, and 37.2 nM against human CA II. Methyl acetazolamide can be used for the research of enterococcus infections .
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
