149104-90-5
149104-90-5
Chemical Structure
4-Acetylphenylboronic acid
- CAS No.: 149104-90-5
- Formula:C8H9BO3
- Molecular Weight:163.97
IUPAC Name: (4-acetylphenyl)boronic acid
InChIKey: OBQRODBYVNIZJU-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(B(O)O)C=C1)C
Biological Activity: 4-Acetylphenylboronic acid is a potent inhibitor of carbonic anhydrases II(CA II), with IC50s of 246 μM and 281.40 μM for bovine CA II (bCA II) and human CA II (hCA II). 4-Acetylphenylboronic acid can be obtained via mechanochemistry and solvent evaporation. 4-Acetylphenylboronic acid has a loss of the carbonyl group at 500-550 K[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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4-Acetylphenylboronic acid | 99.67% | 4-Acetylphenylboronic acid is a potent inhibitor of carbonic anhydrases II(CA II), with IC50s of 246 μM and 281.40 μM for bovine CA II (bCA II) and human CA II (hCA II). 4-Acetylphenylboronic acid can be obtained via mechanochemistry and solvent evaporation. 4-Acetylphenylboronic acid has a loss of the carbonyl group at 500-550 K. | ||||||||||||||||||||
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References
- [1]. Saima Rasheed, et al. Identification, crystallization, and first X-ray structure analyses of phenyl boronic acid-based inhibitors of human carbonic anhydrase-II. Int J Biol Macromol. 2024 May;267(Pt 1):131268. [Content Brief]
- [2]. Ofelia Hernández-Negrete, et al., New hydrate cocrystal of l-proline with 4-acetylphenylboronic acid obtained via mechanochemistry and solvent evaporation: An experimental and theoretical study, Journal of Solid State Chemistry, Volume 313, 2022.
- [3]. Alexander Wolfram, et al., Adsorption of Phenylboronic Acid Derivatives on Rutile TiO2(110) J. Phys. Chem. C 2024, 128, 30, 12450–12470.
Keywords
