JNJ-26990990
JNJ-26990990 is a broad-spectrum antiepileptic agent with oral activity. JNJ-26990990 can inhibit voltage-gated Na+ channels and N-type Ca2+ channels, but has a very weak inhibitory effect on human carbonic anhydrase-II (IC50 = 110 μM).
For research use only. We do not sell to patients.
- CAS No.: 877316-38-6
- Formula: C9H10N2O2S2
- Molecular Weight:242.32
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Calcium Channel Isoforms
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
133 μM
Compound: 4a, JNJ-26990990
|
Inhibition of rat Cav2.2 channel expressed in 0.07 Hz frequency-stimulated HEK cells by whole-cell patch-clamp technique
Inhibition of rat Cav2.2 channel expressed in 0.07 Hz frequency-stimulated HEK cells by whole-cell patch-clamp technique
|
[PMID: 19388676] |
Chemical Information
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CAS No. 877316-38-6
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Molecular Weight 242.32
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Formula C9H10N2O2S2
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SMILES
O=S(N)(NCC1=CSC2=CC=CC=C21)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)