JNJ-26990990
JNJ-26990990 is a broad-spectrum antiepileptic agent with oral activity. JNJ-26990990 can inhibit voltage-gated Na+ channels and N-type Ca2+ channels, but has a very weak inhibitory effect on human carbonic anhydrase-II (IC50 = 110 μM).
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 877316-38-6
- Fòrmula: C9H10N2O2S2
- Peso molecular:242.32
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
133 μM
Compound: 4a, JNJ-26990990
|
Inhibition of rat Cav2.2 channel expressed in 0.07 Hz frequency-stimulated HEK cells by whole-cell patch-clamp technique
Inhibition of rat Cav2.2 channel expressed in 0.07 Hz frequency-stimulated HEK cells by whole-cell patch-clamp technique
|
[PMID: 19388676] |
Chemical Information
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No. CAS 877316-38-6
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Peso molecular 242.32
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Fòrmula C9H10N2O2S2
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SMILES
O=S(N)(NCC1=CSC2=CC=CC=C21)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)