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Art. -Nr.: HY-184759

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Methyl acetazolamide

Name: Methyl acetazolamide
Brand: MedChemExpress
SKU: HY-184759
Availability: PreOrder

(Synonyms: Propazolamide)

Methyl acetazolamide (Propazolamide) is a carbonic anhydrase inhibitor with K_i values of 37.5 nM against Enterococcus faecium α-CA, 250.1 nM against Enterococcus faecium γ-CA, 235.4 nM against human CA I, and 37.2 nM against human CA II. Methyl acetazolamide can be used for the research of enterococcus infections.

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CAS. Nr.: 98-75-9
Formel: C₅H₈N₄O₃S₂
Molecular Weight:236.27

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Methyl acetazolamide Chemical Structure

CAS. Nr.: 98-75-9

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Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

IC₅₀ & Target

^[1]

hCA I

235.4 nM (Ki)

hCA II

37.2 nM (Ki)

Alle Carbonic Anhydrase Isoform-spezifische Produkte anzeigen :

In Vitro

Methyl acetazolamide (compound 1) inhibits recombinant Efa-CA (K_i = 37.5 nM), recombinant Efc-CA (K_i = 250.1 nM), purified hCA I (K_i = 235.4 nM), and purified hCA II (K_i = 37.2 nM), with enhanced potency relative to Acetazolamide (HY-B0782) against the bacterial carbonic anhydrase isoforms^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 98-75-9
Molecular Weight 236.27
Formel C₅H₈N₄O₃S₂
SMILES

O=C(CC)NC1=NN=C(S(=O)(N)=O)S1
Synonyms

Propazolamide
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. An W W, et al. Structure-activity relationship studies for inhibitors for vancomycin-resistant Enterococcus and human carbonic anhydrases. Journal of Enzyme Inhibition and Medicinal Chemistry, 2022, 37(1): 1838-1844.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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