α-Hydroxyglutaric acid disodium (Standard)
Ophiopogonin D (Standard) is the analytical standard of Ophiopogonin D. This product is intended for research and analytical applications. Ophiopogonin D, isolated from the tubers of Ophiopogon japonicus, is a rare naturally occurring C29 steroidal glycoside. Ophiopogonin D is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation, IκBα down-regulation, intracellular Ca2+ overload and activation of pro-inflammatory cytokines by increasing the expression of CYP2J2/EETs and PPARα in human umbilical vein endothelial cells (HUVECs). Ophiopogonin D has been used to treat inflammatory and cardiovascular diseases for thousands of years.
For research use only. We do not sell to patients.
- CAS No.: 40951-21-1
- Formula: C5H6Na2O5
- Molecular Weight:192.08
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 40951-21-1
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Molecular Weight 192.08
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Formula C5H6Na2O5
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SMILES
O=C(O[Na])C(O)CCC(O[Na])=O
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Synonyms
2-Hydroxyglutarate disodium (Standard); 2-Hydroxyglutaric acid disodium (Standard); 2-Hydroxypentanedioic acid disodium (Standard)
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Keywords
- α-Hydroxyglutaric acid disodium (Standard)
- 40951-21-1
- 2-Hydroxyglutarate disodium (Standard)
- 2-Hydroxyglutaric acid disodium (Standard)
- 2-Hydroxypentanedioic acid disodium (Standard)
- Reference Standards
- Histone Demethylase
- Endogenous Metabolite
- Cell-permeable
- 5-methylcytosine
- α-ketoglutarate
- dioxygenases
- IDH1
- IDH2
- Inhibitor
- inhibitor
- inhibit