3 Results for "

human OA cartilage

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "human OA cartilage" in MCE Product Catalog:

  • Targets Recommended:
Cat. No.: HY-P11800
CAS No.: 915404-04-5
Target:  

MMP

Research Areas:  

Inflammation/Immunology

GPLGVRG is an MMP13-responsive linker peptide. GPLGVRG can be hydrolyzed by MMP13, which in turn triggers micellar disintegration, loss of amphipathicity, and increases the chondrocyte uptake rate of the related delivery system. GPLGVRG can be used in the research of osteoarthritis .
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Cat. No.: HY-P10739C
CAS No.: 1027630-05-2
Target:  

Collagen Apoptosis

Research Areas:  

Inflammation/Immunology

WYRGRLC is a type II collagen-targeting peptide. WYRGRLC specifically binds to type II collagen α1 in articular cartilage in a sequence-dependent manner. WYRGRLC inhibits the binding of WYRGRL-displaying phage (C1-3) to articular cartilage in a sequence-specific manner. WYRGRLC can act as a retention enhancer to improve the cartilage-targeting ability of polymeric nanoparticles and liposomal nanoplatforms, facilitating the delivery of Rapamycin (HY-10219) to chondrocytes. WYRGRLC can be used in studies related to osteoarthritis .
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Cat. No.: HY-P11800A
CAS No.: 1257658-47-1
Target:  

Exosomes MMP

Research Areas:  

Inflammation/Immunology

GPLGVRGC is a cysteine-tagged variant of GPLGVRG (HY-P11800). GPLGVRGC is hydrolyzable by MMP13. GPLGVRGC mediates the disassembly of micelle-exosome systems, enhances chondrocyte endocytosis, and promotes responsive system uptake. GPLGVRGC confers targeted delivery and responsive release properties to micelle-exosome systems. GPLGVRGC is applicable to the research of osteoarthritis .
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