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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
17 Results for "
human alkaline phosphatases
" in MedChemExpress (MCE) Product Catalog:
Products (17)
17 Results for "human alkaline phosphatases" in MCE Product Catalog:
11
11 Publications Verification
Synonyms: 2-Phospho-L-ascorbic acid magnesium; LAA2P magnesium
11
11 Publications Verification
Synonyms: 2-Phospho-L-ascorbic acid trisodium
11
11 Publications Verification
Synonyms: 2-Phospho-L-ascorbic acid; LAA2P
11
11 Publications Verification
Synonyms: 2-Phospho-L-ascorbic acid magnesium hydrate; LAA2P magnesium hydrate
2
2 Cited Publications
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DIPQUO is an activator of the bone marker alkaline phosphatase (ALP), with an EC50 of 6.27 μM in C2C12 cells. DIPQUO promotes mouse and human osteoblast differentiation via activation of p38 MAPK-β .
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1 Cited Publications
Synonyms: Lumi-Phos Plus; Lumigen PPD; PPD
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1 Cited Publications
Cat. No.: HY-19695
CAS No.: 62284-79-1
Synonyms: L-p-Bromotetramisole oxalate; 6-Bromolevamisole oxalate
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Ethyl gentisate (Ethyl 2,5-dihydroxybenzoate) is a dual modulator for cell differentiation, that enhances the osteogenic differentiation of human mesenchymal stem cells (hMSCs) and alkaline phosphatase activity, inhibits RANKL-activated osteoclastogenesis in RAW264.7 cells, and balances the bone remodeling process .
Cat. No.: HY-161916
CAS No.: 3043810-73-4
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Polθ-IN-4 is an orally active prodrug of a DNA polymerase θ (Polθ) inhibitor with Kms of 3.7, 3.7 and 5.2 μM in human, mouse and rat recombinant alkaline phosphatases. Polθ-IN-4 that inhibits Polθ activity by targeting its ATP-dependent helicase domain. Polθ-IN-4 demonstrates significant anti-tumor activity in multiple animal experiments. Polθ-IN-4 can be used for the studies of breast cancer and ovarian cancer .
Cat. No.: HY-103701AR
CAS No.: 113170-55-1
Synonyms: 2-Phospho-L-ascorbic acid magnesium (Standard); LAA2P magnesium (Standard)
Cat. No.: HY-P4835
CAS No.: 247902-18-7
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Cat. No.: HY-W141781
CAS No.: 3724-89-8
Synonyms: Cystaphos sodium
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Cat. No.: HY-183407
CAS No.: 50648-52-7
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R 8231 is a reversible inhibitor of Alkaline Phosphatase. R 8231 potently inhibits alkaline phosphatases derived from human liver, bone, kidney and spleen, while exerts weak effects on those derived from human intestine and placenta. The IC50 value of R 8231 for inhibiting bone alkaline phosphatase from adult rabbits is approximately 1 μM, whereas that for inhibiting chicken bone alkaline phosphatase is approximately 100 μM. R 8231 can be used for alkaline phosphatase histochemistry, phosphatase activity identification and bone metabolism-related studies .
Cat. No.: HY-107837R
CAS No.: 66170-10-3
Synonyms: 2-Phospho-L-ascorbic acid trisodium (Standard)
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Alkaline phosphatase (Apase), Human (HEK293) is an orally active membrane-bound glycoprotein that catalyzes the hydrolysis of phosphate monoesters at alkaline pH. Alkaline phosphatase reduces myeloperoxidase activity and bacterial translocation. Alkaline phosphatase improves survival rate of mice infected with E. coli. Alkaline phosphatase improves TNBS-induced colon inflammation .
Cat. No.: HY-119080
CAS No.: 532435-68-0
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CP8754 is an orally active, selective human progesterone receptor (hPR) antagonist that blocks progesterone-mediated signaling pathways. CP8754 competitively inhibits the binding of [ 3H]-progesterone to hPR. And in vitro, CP8754 inhibits progesterone-dependent exogenous luciferase and endogenous alkaline phosphatase expression; while in vivo, CP8754 inhibits rabbit endometrial transformation. CP8754 does not significantly bind to human glucocorticoid receptors (hGR), estrogen receptors (hER), or rat androgen receptors (rAR). CP8754 can be used in the study of progesterone-related diseases such as breast cancer, endometriosis, uterine fibroids, and meningioma, as well as hormone-dependent tumors .
Cat. No.: HY-184701
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α-Glucosidase-IN-119 is an α-glucosidase inhibitor with an IC50 of 3.32 μM and oral effectiveness. α-Glucosidase-IN-119 acts as an antihyperglycemic agent, reduces blood glucose levels, restores normal levels of alkaline phosphatase, aspartate transaminase, alanine transaminase, urea, blood urea nitrogen, and total protein, and exhibits antioxidant activity. α-Glucosidase-IN-119 can be used for the research of type 2 diabetes mellitus .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
