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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
38 Results for "
human aromatase
" in MedChemExpress (MCE) Product Catalog:
Products (38)
38 Results for "human aromatase" in MCE Product Catalog:
7
7 Publications Verification
Synonyms: FCE 24304; EXE
Target:
Research Areas:
Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal aromatase inhibitor with IC50s of 30 nM and 40 nM for human placental and rat ovarian aromatase, respectively. Exemestane can be used for hormone-dependent breast cancer research .
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Anastrozole is a potent, highly selective aromatase inhibitor, which inhibits human placental aromatase with an IC50 of 15 nM.
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Environmental Pollutants Estrogen Receptor/ERR Aryl Hydrocarbon Receptor Fungal Androgen Receptor
Research Areas:
Prochloraz is an imidazole antifungal. Prochloraz is as an estrogen receptor (ER) and androgen receptor (AR) antagonist and an aromatase inhibitor with IC50 values of 25 μM, 4 μM and 0.3 μM, respectively. Prochloraz is able to activate the aryl hydrocarbon receptor (AhR) having an EC50 of 1 μM .
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Synonyms: (R)-Fadrozole; (R)-CGS 16949A free base; FAD286
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Dexfadrostat ((R)-Fadrozole) is an orally active and selective aromatase inhibitor, with human aromatase IC50 values of 6.4 nM. Dexfadrostat suppresses estrogen synthesis, reduces circulating estradiol levels and suppresses aldosterone production. Dexfadrostat can be used for the research of breast cancer, primary aldosteronism, and hypertension .
Cat. No.: HY-N8487
CAS No.: 22395-22-8
Category:
Flavonoids Neurological Disease Leguminosae Flavones Zornia brasiliensis Plants Disease Research Fields Inflammation/Immunology
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Category:
Flavonols other families Flavonoids Metabolic Disease Phenols Polyphenols Plants Disease Research Fields
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Mefentrifluconazole is a novel azole derivative and used as an agrochemical broad-spectrum antifungal agent. Mefentrifluconazole is a potent, selective and orally active fungal CYP51 (Kd= 0.5 nM) inhibitor, but shows less inhibitory activity on human aromatase (IC50=0.92 μM) .
Cat. No.: HY-14274R
CAS No.: 120511-73-1
Synonyms: ZD1033 (Standard)
Target:
Research Areas:
Anastrozole (Standard) is the analytical standard of Anastrozole. This product is intended for research and analytical applications. Anastrozole is a potent, highly selective aromatase inhibitor, which inhibits human placental aromatase with an IC50 of 15 nM.
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4-Pyridylmethyl adamantanecarboxamide (Compound 11) is an Aromatase inhibitor with an IC50 of 1.5 μM against hAromatase. 4-Pyridylmethyl adamantanecarboxamide inhibits the C17,20-lyase activity of testicular cytochrome P45017α with an IC50 of 1600 nM, and also inhibits the 17α-hydroxylase activity of this enzyme with an IC50 of 7700 nM. 4-Pyridylmethyl adamantanecarboxamide can be used in the research of prostate cancer .
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YM511 is a highly specific non-steroidal aromatase inhibitor. YM511 inhibits aromatase activities in microsomes from rat ovary and human placenta competitively (IC50s of 0.4 and 0.12 nM, respectively). YM511 slightly inhibits production of other steroid hormones. YM511 has the potential for suppressing estrogen-dependent action research without affecting serum levels of other steroid hormones .
Cat. No.: HY-14274S
CAS No.: 120512-32-5
Synonyms: ZD1033-d12
Synonyms: FCE 24304(Standard); EXE (Standard)
Target:
Research Areas:
Exemestane (Standard) is the analytical standard of Exemestane. This product is intended for research and analytical applications. Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal aromatase inhibitor with IC50s of 30 nM and 40 nM for human placental and rat ovarian aromatase, respectively. Exemestane can be used for hormone-dependent breast cancer research .
Cat. No.: HY-W329835
CAS No.: 114369-43-6
Fenbuconazole is a triazole fungicide that has fungicidal activity through inhibiting sterol biosynthesis. Fenbuconazole is an inhibitor of human aromatase activity in human choriocarcinoma JEG-3 cell line. Fenbuconazole can result in a significant increase in DNA damage in Allium cepa root cells. Fenbuconazole significantly increases the abnormal cell frequency in vitro. Fenbuconazole exhibits ED50 of 0.21 μg/mL with M.citri and 1.01 μg/mL with C. acutatum .
Cat. No.: HY-13632S
Synonyms: FCE 24304-d2; EXE-d2
Cat. No.: HY-13632S2
Synonyms: FCE 24304-d3; EXE-d3
Cat. No.: HY-13632S1
CAS No.: 1092371-24-8
Synonyms: FCE 24304-13C3; EXE-13C3
Cat. No.: HY-13632S6
Synonyms: FCE 24304-d4; EXE-d4
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
