1 Result for "

human short-form FFAR4

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "human short-form FFAR4" in MCE Product Catalog:

Cat. No.: HY-121212
CAS No.: 1253909-57-7
Purity:  97.28%
Icosabutate is an orally active engineered fatty acid and a dual FFAR1/FFAR4 (GPR40/GPR120) agonist with EC50 values of 10 μM and 15.5 μM, respectively. Icosabutate acts as a partial agonist of PPAR-α, with an EC50 of 208 nM. Icosabutate inhibits the arachidonic acid cascade and exhibits antioxidant and anti-apoptotic activities. Icosabutate can be used in the research of nonalcoholic steatohepatitis, metabolic dysfunction-associated steatohepatitis, and atherosclerosis .
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