2 Results for "

hypophosphatasia

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "hypophosphatasia" in MCE Product Catalog:

Cat. No.: HY-108786
CAS No.: 1174277-80-5
Purity:  97.88%
Synonyms: ENB-0040

Target:  

Phosphatase

Research Areas:  

Metabolic Disease

Asfotase alfa (ENB-0040) is a bone-targeted genetically engineered glycoprotein. Asfotase alfa increases the survival rate, bone mineralization and bone length and prevents mineralization defects of the feet, rib cage, lower limbs, jaw bones in Akp2 / knockout mice. Asfotase alfa can be used for the research of perinatal, infantile, and juvenile-onset hypophosphatasia (HPP) .
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Cat. No.: HY-P991210
CAS No.: 2746354-58-3
Synonyms: ALXN-1850

Target:  

Phosphatase

Research Areas:  

Cardiovascular Disease

Efzimfotase alfa (ALXN-1850) is enzyme replacement therapy agent targeting the deficiency of tissue-nonspecific alkaline phosphatase (TNSALP). Efzimfotase alfa functions by hydrolyzing the substrates of TNSALP, reducing the concentrations of substrates such as inorganic pyrophosphate (PPi) and pyridoxal 5′-phosphate (PLP). Efzimfotase alfa is promising for research of hypophosphatasia (HPP) .
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