20 Results for "

immunomodulating activities

" in MedChemExpress (MCE) Product Catalog:
Products (20)

20 Results for "immunomodulating activities" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-119109
CAS No.: 9008-22-4
Purity:  ≥98.0%
Laminaran is an β-1-3-glucan and a typical ligand for Dectin-1 from Eisenia Bicyclis, has potent immunomodulating, radioprotective, and anticancer activities . Laminaran is made up of β (1→3)-glucan with β (1→6)-branches and can be catalyzed by enzymes such as laminarinase (EC 3.2.1.6) that breaks the β (1→3) bonds . Laminaran is a promising immune stimulatory molecule for use in cancer immunotherapy .
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Cat. No.: HY-109082
CAS No.: 1703788-21-9
Purity:  99.58%
Synonyms: SKI-O-703
Target:  

Syk

Research Areas:  

Inflammation/Immunology

Cevidoplenib (SKI-O-703) is an orally available inhibitor of spleen tyrosine kinase (Syk), with potential anti-inflammatory and immunomodulating activities. Cevidoplenib is also the mesylate form of SKI-O-592. Cevidoplenib and SKI-O-592 inhibits BCR-mediated survival, proliferation, and differentiation of B cells. And SKI-O-592 potently inhibits multiple kinases with IC50s of 6.2 nM (Syk), 1.859 μM (Jak2), 5.807 μM (Jak3), 0.412 μM (RET), 0.687 μM (KOR), 1.783 μM (FLT3), 16.96 μM (FGFR1), 5.662 μM (FGFR3), and 0.709 μM (Pyk2), respectively .
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Cat. No.: HY-P991089

Target:  

CD3

Research Areas:  

Cancer

GEN-1044 is a bispecific CD3 and oncofetal antigen 5T4 antibody. GEN-1044 shows immunomodulating and antineoplastic activities .
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Cat. No.: HY-109082A
CAS No.: 2043659-93-2
Purity:  98.96%
Synonyms: SKI-O-703 dimesylate
Target:  

Syk

Research Areas:  

Inflammation/Immunology

Cevidoplenib is an orally available inhibitor of spleen tyrosine kinase (Syk), with potential anti-inflammatory and immunomodulating activities .
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Cat. No.: HY-14743B
CAS No.: 1029401-59-9
Purity:  99.64%
Synonyms: SCV 07 hydrochloride; Gamma-D-glutamyl-L-tryptophan hydrochloride
Target:  

Bacterial STAT

Golotimod hydrochloride (SCV 07 hydrochloride), an immunomodulating peptide with antimicrobial activity, significantly increases the efficacy of antituberculosis therapy, stimulates thymic and splenic cell proliferation, and improves macrophage function. Golotimod hydrochloride (SCV 07 hydrochloride) inhibits STAT3 signaling and modulates the duration and severity of oral mucositis in animal models that received radiation or a combination of radiation and Cisplatin. Golotimod hydrochloride (SCV 07 hydrochloride) is also a potential therapeutic for recurrent genital herpes simplex virus type 2 (HSV-2) .
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Cat. No.: HY-106765A
Purity:  99.94%
Synonyms: RGH-0205 TFA; TP3 TFA
Target:  

Peptides

Research Areas:  

Inflammation/Immunology

Thymotrinan (RGH-0205) TFA is a biologically active fragment of the naturally occurring thymus hormone thymopoietin and a immunomodulating peptide. Thymotrinan TFA exerts similar immunomodulatory activities to TP5 and to affect humoral as well as cellular responses .
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Cat. No.: HY-14743
CAS No.: 229305-39-9
Purity:  98.04%
Synonyms: SCV 07; Gamma-D-glutamyl-L-tryptophan
Target:  

Bacterial STAT

Golotimod (SCV-07), an immunomodulating peptide with antimicrobial activity, significantly increases the efficacy of antituberculosis therapy, stimulates thymic and splenic cell proliferation, and improves macrophage function. Golotimod (SCV-07) inhibits STAT3 signaling and modulates the duration and severity of oral mucositis in animal models that received radiation or a combination of radiation and Cisplatin. Golotimod (SCV-07) is also a potential therapeutic for recurrent genital herpes simplex virus type 2 (HSV-2) .
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Cat. No.: HY-P3315
CAS No.: 1164096-85-8
Synonyms: RV001
Target:  

Peptides

Research Areas:  

Inflammation/Immunology Cancer

Onilcamotide (RV001) is a C-terminal peptide of RhoC protein. Onilcamotide is a cancer vaccine and has potential immunomodulating and antineoplastic activities .
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Cat. No.: HY-N4129
CAS No.: 950910-16-4
4''-methyloxy-Genistin, an isoflavone methyl-glycoside, is isolated from Cordyceps militaris grown on germinated soybeans. Isoflavones possess immunomodulating and antiallergic activities .
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Cat. No.: HY-106765
CAS No.: 85465-82-3
Synonyms: RGH-0205; TP3
Target:  

Peptides

Research Areas:  

Inflammation/Immunology

Thymotrinan (RGH-0205) is a biologically active fragment of the naturally occurring thymus hormone thymopoietin and a immunomodulating peptide. Thymotrinan exerts similar immunomodulatory activities to TP5 and to affect humoral as well as cellular responses .
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Cat. No.: HY-106050
CAS No.: 58433-11-7
Synonyms: Wy 18251
Target:  

COX

Research Areas:  

Inflammation/Immunology Cancer

Tilomisole (Wy 18251) is a benzimidazothiazole experimental agent with anti-inflammatory activity. Tilomisole causes less agranulocytosis than levamisole, but retains immunomodulating capabilities. Tilomisole is orally active. Tilomisole has the potential for the research of cancer and inflammation .
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Cat. No.: HY-N4128
CAS No.: 1195968-02-5
Synonyms: Daidzein 7-O-Β-D-glucoside 4''-O-methylate
4''-methyloxy-Daidzin (Daidzein 7-O-Β-D-glucoside 4''-O-methylate), an isoflavone methyl-glycoside, is isolated from Cordyceps militaris grown on germinated soybeans. Isoflavones possess immunomodulating and antiallergic activities .
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Cat. No.: HY-12616
CAS No.: 1062670-13-6
Target:  

LPL Receptor

Research Areas:  

Cancer

ACT-209905 is a S1P1 receptor agonist. ACT-209905 can inhibit glioblastoma (GBM) cell growth and migration. ACT-209905 also has immunomodulating activity, and can be used in research of autoimmune diseases .
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Cat. No.: HY-121619
CAS No.: 28872-28-8
Jacaric acid is a conjugated linolenic acid, which inhibits viability in cells PC-3 (IC50 is 11.8 μM), LNCaP (IC50 is 2.2 μM) and DLD-1, induces apoptosis and necrosis . Jacaric acid exhibits anticaner activity against prostate cancer and adenocarcinoma . Jacaric acid exhibits immunomodulating activity in murine peritoneal macrophages as an immunopotentiator . Jacaric acid is orally active.
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Cat. No.: HY-14743A
CAS No.: 2828433-07-2
Synonyms: SCV 07 TFA; Gamma-D-glutamyl-L-tryptophan TFA
Target:  

Bacterial STAT

Golotimod TFA (SCV 07 TFA), an immunomodulating peptide with antimicrobial activity, significantly increases the efficacy of antituberculosis therapy, stimulates thymic and splenic cell proliferation, and improves macrophage function. Golotimod TFA (SCV 07 TFA) inhibits STAT3 signaling and modulates the duration and severity of oral mucositis in animal models that received radiation or a combination of radiation and Cisplatin. Golotimod TFA (SCV 07 TFA) is also a potential therapeutic for recurrent genital herpes simplex virus type 2 (HSV-2) .
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Cat. No.: HY-14743R
CAS No.: 229305-39-9
Synonyms: SCV 07 (Standard); Gamma-D-glutamyl-L-tryptophan (Standard)
Golotimod (Standard) is the analytical standard of Golotimod. This product is intended for research and analytical applications. Golotimod (SCV-07), an immunomodulating peptide with antimicrobial activity, significantly increases the efficacy of antituberculosis therapy, stimulates thymic and splenic cell proliferation, and improves macrophage function. Golotimod (SCV-07) inhibits STAT3 signaling and modulates the duration and severity of oral mucositis in animal models that received radiation or a combination of radiation and Cisplatin. Golotimod (SCV-07) is also a potential therapeutic for recurrent genital herpes simplex virus type 2 (HSV-2) .
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Cat. No.: HY-109082AR
CAS No.: 2043659-93-2
Synonyms: SKI-O-703 dimesylate (Standard)
Target:  

Reference Standards Syk

Research Areas:  

Inflammation/Immunology

Cevidoplenib dimesylate (Standard) is the analytical standard of Cevidoplenib (dimesylate) (HY-109082A). This product is intended for research and analytical applications. Cevidoplenib is an orally available inhibitor of spleen tyrosine Kinase (Syk), with potential anti-inflammatory and immunomodulating activities .
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Cat. No.: HY-P992022

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology Cancer

AK114 is an anti-human interleukin-1 beta (IL-1β) imonoclonal antibody. AK114 binds to interleukin-1 beta and prevents its binding to the IL-1 receptor, suppresses inflammatory responses, tumorigenesis, and angiogenesis mediated by interleukin-1 beta.AK114 exhibits anti-inflammatory, immunomodulating, and antineoplastic activities .
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Cat. No.: HY-W744192
CAS No.: 112668-45-8
Synonyms: R-842
2-Hydroxy Imiquimod (R-842), a hydroxylated metabolite of Imiquimod (HY-B0180), is an immunomodulating agent. 2-Hydroxy Imiquimod can induce IFN-α, TNF-α, IL-1, IL-6 and IL-8 in human blood cells. 2-Hydroxy Imiquimod exhibits antivirus and antitumor activities. 2-Hydroxy Imiquimod can be used for the researches of cancer, infection and immunology .
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Cat. No.: HY-109082R
CAS No.: 1703788-21-9
Synonyms: SKI-O-703 (Standard)
Target:  

Reference Standards Syk

Research Areas:  

Inflammation/Immunology

Cevidoplenib (Standard) is the analytical standard of Cevidoplenib (HY-109082). This product is intended for research and analytical applications. Cevidoplenib (SKi-O-703) is an orally available inhibitor of spleen tyrosine Kinase (Syk), with potential anti-inflammatory and immunomodulating activities. Cevidoplenib is also the mesylate form of SKi-O-592. Cevidoplenib and SKi-O-592 inhibits BCR-mediated survival, proliferation, and differentiation of B cells. And SKi-O-592 potently inhibits multiple Kinases with IC50s of 6.2 nM (Syk), 1.859 μM (Jak2), 5.807 μM (Jak3), 0.412 μM (RET), 0.687 μM (KOR), 1.783 μM (FLT3), 16.96 μM (FGFR1), 5.662 μM (FGFR3), and 0.709 μM (Pyk2), respectively .
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