301 Results for "

interleukin 1

" in MedChemExpress (MCE) Product Catalog:
Products (301)

301 Results for "interleukin 1" in MCE Product Catalog:

58
58 Publications Verification
Cat. No.: HY-P7028
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1B; IL-1B; interleukin 1 Beta; Multifunctional Fusion Protein; IL1F2; Pro-interleukin-1-Beta; interleukin-1 Beta; Preinterleukin 1 Beta; IL1-BETA; interleukin 1beta; IL-1 Beta; IL1beta; Catabolin; IL-1
Species:  
Source:  
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56
56 Cited Publications
Cat. No.: HY-108841
CAS No.: 143090-92-0
Purity:  99.40%
Synonyms: Kineret; Anakinra
Raleukin (Kineret) is a recombinant, nonglycosylated human interleukin-1 receptor (IL-1R) antagonist. Raleukin significantly reduces neutrophil accumulation in blood vessels and brain infarct volume as well as improves motor coordination performance in ischemic stroke mice model. Anakinra can be used to study chronic inflammatory disorders like rheumatoid arthritis and cardiovascular recurrence post-myocardial infarction .
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45
45 Cited Publications
Cat. No.: HY-P7073
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1B; IL-1B; interleukin 1 Beta; Multifunctional Fusion Protein; IL1F2; Pro-interleukin-1-Beta; interleukin-1 Beta; Preinterleukin 1 Beta; IL1-BETA; interleukin 1beta; IL-1 Beta; IL1beta; Catabolin; IL-1
Species:  
Source:  
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23
23 Cited Publications
Cat. No.: HY-P7097
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1B; IL-1B; interleukin 1 Beta; Multifunctional Fusion Protein; IL1F2; Pro-interleukin-1-Beta; interleukin-1 Beta; Preinterleukin 1 Beta; IL1-BETA; interleukin 1beta; IL-1 Beta; IL1beta; Catabolin; IL-1
Species:  
Rat
Source:  
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22
22 Cited Publications
Cat. No.: HY-P80622
Synonyms: CASP1; IL1BC; IL1BCE; Caspase-1; CASP-1; interleukin-1 beta convertase; IL-1BC; interleukin-1 beta-converting enzyme; ICE; IL-1 beta-converting enzyme; p45

Host:  

Rabbit

Application:  

WB, ICC/IF, IHC-F, IHC-P, ELISA

Reactivity:  

Human, Mouse

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14
14 Cited Publications
Cat. No.: HY-P7218
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL33; DVS27-Related Protein; Prev. C9orf26; Chromosome 9 Open Reading Frame 26 (NF-HEV); NF-HEV; interleukin-1 Family, Member 11; IL1F11; Alternative Protein IL33; interleukin-33; IL-1F11; DVS27; NFEHEV; Nuclear Factor From High Endothelial Venules; IL-33
Species:  
Source:  
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11
11 Cited Publications
Cat. No.: HY-13329
CAS No.: 509093-47-4
Purity:  99.90%
Synonyms: IRAK-1/4 Inhibitor I
Target:  

IRAK

Research Areas:  

Inflammation/Immunology

IRAK-1-4 Inhibitor I is an inhibitor of interleukin-1 receptor-associated kinase 1/4 (IRAK 1/4) with IC50s of 0.2 μM and 0.3 μM, respectively.
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10
10 Cited Publications
Cat. No.: HY-19975
CAS No.: 946387-07-1
Target:  

TRP Channel

Research Areas:  

Neurological Disease Cancer

RN-1734 is selective antagonist of the TRPV4 channel, completely antagonizes 4αPDD-mediated activation of TRPV4 with comparable, low micromolar IC50s for all three species (hTRPV4: 2.3 μM, mTRPV4: 5.9 μM, rTRPV4: 3.2 μM) . RN-1734 clearly decreases the production of tumor necrosis factor α (TNF-α) and interleukin 1β (IL-1β) without altering the number of olig2-positive cells .
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9
9 Cited Publications
Cat. No.: HY-P72566
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1RN; IL-1ra; interleukin 1 Receptor Antagonist; Intracellular interleukin-1 Receptor Antagonist (IcIL-1ra); ICIL-1RA; Intracellular interleukin-1 Receptor Antagonist; IL-1RN; Intracellular IL-1 Receptor Antagonist Type II; IL1RA; Type II interleukin-1 R
Species:  
Source:  
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9
9 Cited Publications
Cat. No.: HY-P73149
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1B; IL-1B; interleukin 1 Beta; Multifunctional Fusion Protein; IL1F2; Pro-interleukin-1-Beta; interleukin-1 Beta; Preinterleukin 1 Beta; IL1-BETA; interleukin 1beta; IL-1 Beta; IL1beta; Catabolin; IL-1
Species:  
Source:  
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7
7 Cited Publications
Cat. No.: HY-19836
CAS No.: 1817626-54-2
Synonyms: PF-06650833
Target:  

IRAK

Research Areas:  

Inflammation/Immunology

Zimlovisertib (PF-06650833) is a potent, selective and orally active inhibitor of interleukin-1 receptor associated kinase 4 (IRAK4) with IC50s of 0.2 and 2.4 nM in the cell and PBMC assay, respectively. Zimlovisertib is used to treat diseases such as rheumatoid arthritis, lupus, and lymphomas .
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7
7 Cited Publications
Cat. No.: HY-P81232
Synonyms: caspase-1 isoform alpha subunit; CASP1; ICE; IL1BC; Caspase-1 subunit p20; CASP 1; Caspase 1 apoptosis related cysteine peptidase; Caspase 1 apoptosis related cysteine protease; Caspase1; IL 1 beta converting enzyme; IL 1BC; IL1B convertase; IL1BCE; interleukin 1 beta convertase; interleukin 1 beta convertase precursor; interleukin 1 beta converting enzyme; CASP-1; interleukin-1 beta convertase; IL-1BC; interleukin-1 beta-converting enzyme; ICE; IL-1 beta-converting enzyme; p45; CASP1_HUMAN; CASP1_MOUSE.

Host:  

Rabbit

Application:  

WB, IHC-P, IHC-F, ICC/IF, FC

Reactivity:  

Human, Mouse, Rat

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6
6 Cited Publications
Cat. No.: HY-103017A
CAS No.: 2227368-54-7
Purity:  99.03%
Target:  

IRAK

JH-X-119-01 is a potent and selective interleukin-1 receptor-associated kinases 1 (IRAK1) inhibitor. JH-X-119-01 ameliorates LPS-induced sepsis in mice . JH-X-119-01 inhibits IRAK1 biochemically with an apparent IC50 of 9 nM while exhibiting no inhibition of IRAK4 at concentrations up to 10 μM .
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6
6 Cited Publications
Cat. No.: HY-103017
CAS No.: 2591344-30-6
Purity:  99.14%
Target:  

IRAK

Research Areas:  

Infection

JH-X-119-01 hydrochloride is a potent and selective interleukin-1 receptor-associated kinases 1 (IRAK1) inhibitor. JH-X-119-01 hydrochloride ameliorates LPS-induced sepsis in mice .
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6
6 Cited Publications
Cat. No.: HY-P7073A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1B; IL-1B; interleukin 1 Beta; Multifunctional Fusion Protein; IL1F2; Pro-interleukin-1-Beta; interleukin-1 Beta; Preinterleukin 1 Beta; IL1-BETA; interleukin 1beta; IL-1 Beta; IL1beta; Catabolin; IL-1
Species:  
Source:  
CHO
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6
6 Cited Publications
Cat. No.: HY-P1110
CAS No.: 185413-30-3
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

AF12198 is a potent, selective and specific peptide antagonist for human type I interleukin-1 receptor (IL1-R1) (IC50=8 nM) but not the human type II receptor (IC50=6.7 µM) or the murine type I receptor (IC50>200 µM). AF12198 inhibits IL-1-induced IL-8 production (IC50=25 nM) and IL-1-induced intercellular adhesion molecule-1 (ICAM-1) expression (IC50=9 nM) in vitro. AF12198 has anti-inflammatory activities and blocks responses to IL-1 in vivo .
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5
5 Cited Publications
Cat. No.: HY-P7029
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1RN; IL-1ra; interleukin 1 Receptor Antagonist; Intracellular interleukin-1 Receptor Antagonist (IcIL-1ra); ICIL-1RA; Intracellular interleukin-1 Receptor Antagonist; IL-1RN; Intracellular IL-1 Receptor Antagonist Type II; IL1RA; Type II interleukin-1 R
Species:  
Source:  
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5
5 Cited Publications
Cat. No.: HY-P7027
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1A; IL-1A; Prev. IL1; Preinterleukin 1 Alpha; IL1F1; interleukin-1 Alpha; Hematopoietin-1; IL-1 Alpha; IL1-ALPHA; interleukin 1 Alpha; Pro-interleukin-1-Alpha
Species:  
Source:  
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5
5 Cited Publications
Cat. No.: HY-P73900
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL1B; IL-1B; interleukin 1 Beta; Multifunctional Fusion Protein; IL1F2; Pro-interleukin-1-Beta; interleukin-1 Beta; Preinterleukin 1 Beta; IL1-BETA; interleukin 1beta; IL-1 Beta; IL1beta; Catabolin; IL-1
Species:  
Rat
Source:  
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5
5 Cited Publications
Cat. No.: HY-P80587
Synonyms: CASP1; IL1BC; IL1BCE; Caspase-1; CASP-1; interleukin-1 beta convertase; IL-1BC; interleukin-1 beta-converting enzyme; ICE; IL-1 beta-converting enzyme; p45

Host:  

Rabbit

Application:  

WB, IHC-P, ELISA

Reactivity:  

Human, Mouse, Rat

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