13 Results for "

modified messenger RNA

" in MedChemExpress (MCE) Product Catalog:
Products (13)

13 Results for "modified messenger RNA" in MCE Product Catalog:

8
8 Publications Verification
Cat. No.: HY-N0086
CAS No.: 1867-73-8
Synonyms: 6-Methyladenosine; N-Methyladenosine
N6-Methyladenosine is the most prevalent internal (non-cap) modification present in the messenger RNA (mRNA) of all higher eukaryotes. N6-Methyladenosine can modifies viral RNAs and has antiviral activities.
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6
6 Cited Publications
Cat. No.: HY-112980
CAS No.: 1258984-36-9
Purity:  97.79%
Target:  

DNA/RNA Synthesis

Research Areas:  

Neurological Disease

Nusinersen is an antisense oligonucleotide active molecule. Nusinersen modifies the pre-messenger RNA splicing of the SMN2 gene, thereby promoting the production of full-length SMN protein. Nusinersen improves spinal muscular atrophy .
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6
6 Cited Publications
Cat. No.: HY-112980A
Purity:  98.91%
Target:  

DNA/RNA Synthesis

Research Areas:  

Neurological Disease

Nusinersen sodium is an antisense oligonucleotide active molecule. Nusinersen sodium modifies the pre-messenger RNA splicing of the SMN2 gene, thereby promoting the production of full-length SMN protein. Nusinersen sodium improves spinal muscular atrophy .
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2
2 Cited Publications
Cat. No.: HY-N0086R
CAS No.: 1867-73-8
Synonyms: 6-Methyladenosine (Standard); N-Methyladenosine (Standard)
N6-Methyladenosine (Standard) is the analytical standard of N6-Methyladenosine. This product is intended for research and analytical applications. N6-Methyladenosine is the most prevalent internal (non-cap) modification present in the messenger RNA (mRNA) of all higher eukaryotes. N6-Methyladenosine can modifies viral RNAs and has antiviral activities. In Vitro: N6-methyladenosine (m6A) is selectively recognized by the human YTH domain family 2 (YTHDF2) protein to regulate mRNA degradation. N6-methyladenosine (m6A), a prevalent internal modification in the messenger RNA of all eukaryotes, is post-transcriptionally installed by m6A methyltransferase (e.g., MT-A70) within the consensus sequence of G(m6A)C (70%) or A(m6A)C (30%). N6-methyladenosine (m6A)-containing RNAs are greatly enriched in the YTHDF-bound portion and diminished in the flow-through portion . N6-methyladenosine (m6A), the most abundant internal RNA modification, functions in diverse biological processes, including regulation of embryonic stem cell self-renewal and differentiation. N6-methyladenosine (m6A) is a large protein complex, consisting in part of methyltransferase-like 3 (METTL3) and methyltransferase-like 14 (METTL14) catalytic subunits .
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1
1 Cited Publications
Cat. No.: HY-147338A
Purity:  99.40%
Synonyms: 5-Methyl-CTP trisodium
Target:  

DNA/RNA Synthesis

Research Areas:  

Inflammation/Immunology

5-Methylcytidine 5′-triphosphate (5-Methyl-CTP) trisodium is a modified ribonucleoside 5′-triphosphate. When incorporated into mRNA, 5-Methylcytidine 5′-triphosphate trisodium enhances the translation efficiency and stability of the mRNA, and reduces the innate immune response. 5-Methylcytidine 5′-triphosphate trisodium can be used in studies related to gene replacement and vaccination applications .
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Cat. No.: HY-N0086S
CAS No.: 139896-43-8
Synonyms: 6-Methyladenosine-d3; N-Methyladenosine-d3
N6-Methyladenosine-d3 (6-Methyladenosine-d3; N-Methyladenosine-d3) is a deuterium labeled N6-Methyladenosine (HY-N0086). N6-Methyladenosine is the most prevalent internal (non-cap) modification present in the messenger RNA (mRNA) of all higher eukaryotes. N6-Methyladenosine can modifies viral RNAs and has antiviral activities.
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Cat. No.: HY-N0086S2
Synonyms: 6-Methyladenosine-13C4; N-Methyladenosine-13C4
N6-Methyladenosine- 13C4 (6-Methyladenosine- 13C4; N-Methyladenosine- 13C4) is 13C-labeled N6-Methyladenosine (HY-N0086). N6-Methyladenosine is the most prevalent internal (non-cap) modification present in the messenger RNA (mRNA) of all higher eukaryotes. N6-Methyladenosine can modifies viral RNAs and has antiviral activities.
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Cat. No.: HY-147338
CAS No.: 327174-86-7
Synonyms: 5-Methyl-CTP
Target:  

DNA/RNA Synthesis

Research Areas:  

Inflammation/Immunology

5-Methylcytidine 5′-triphosphate (5-Methyl-CTP) is a modified ribonucleoside 5′-triphosphate. When incorporated into mRNA, 5-Methylcytidine 5′-triphosphate enhances the translation efficiency and stability of the mRNA, and reduces the innate immune response. 5-Methylcytidine 5′-triphosphate can be used in studies related to gene replacement and vaccination applications .
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Cat. No.: HY-147338S
Synonyms: 5-Methyl-CTP-d3 trisodium
5-Methylcytidine 5′-triphosphate-d3 (5-Methyl-CTP-d3) trisodium is the deuterium labeled 5-Methylcytidine 5’-triphosphate (5-Methyl-CTP) trisodium (HY-147338A). 5-Methylcytidine 5’-triphosphate trisodium is a modified ribonucleoside 5′-triphosphate. When incorporated into mRNA, 5-Methylcytidine 5′-triphosphate trisodium enhances the translation efficiency and stability of the mRNA, and reduces the innate immune response. 5-Methylcytidine 5′-triphosphate trisodium can be used in studies related to gene replacement and vaccination applications .
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Cat. No.: HY-147338S1
Synonyms: 5-Methyl-CTP-15N2, 13C trisodium
5-Methylcytidine 5′-triphosphate-15N2, 13C (5-Methyl-CTP-15N2, 13C) trisodium is the 15N and 13C labled 5-Methylcytidine 5’-triphosphate (5-Methyl-CTP) trisodium (HY-147338A). 5-Methylcytidine 5’-triphosphate trisodium is a modified ribonucleoside 5′-triphosphate. When incorporated into mRNA, 5-Methylcytidine 5′-triphosphate trisodium enhances the translation efficiency and stability of the mRNA, and reduces the innate immune response. 5-Methylcytidine 5′-triphosphate trisodium can be used in studies related to gene replacement and vaccination applications .
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Cat. No.: HY-147338S2
Synonyms: 5-Methyl-CTP-d8 trisodium
5-Methylcytidine 5′-triphosphate-d8 (5-Methyl-CTP-d8) trisodium is the deuterium-labeled 5-Methylcytidine 5’-triphosphate (5-Methyl-CTP) trisodium (HY-147338A). 5-Methylcytidine 5’-triphosphate trisodium is a modified ribonucleoside 5′-triphosphate. When incorporated into mRNA, 5-Methylcytidine 5′-triphosphate trisodium enhances the translation efficiency and stability of the mRNA, and reduces the innate immune response. 5-Methylcytidine 5′-triphosphate trisodium can be used in studies related to gene replacement and vaccination applications .
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Cat. No.: HY-N0086S3
Synonyms: 6-Methyladenosine-13C3; N-Methyladenosine-13C3
N6-Methyladenosine- 13C3 (6-Methyladenosine- 13C3) is 13C-labeled N6-Methyladenosine (HY-N0086). N6-Methyladenosine is the most prevalent internal (non-cap) modification present in the messenger RNA (mRNA) of all higher eukaryotes. N6-Methyladenosine can modifies viral RNAs and has antiviral activities .
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Cat. No.: HY-177992
CAS No.: 1863930-80-6
Research Areas:  

Others

Cyclic-di-DAP is a base-modified analogue of c-di-AMP (HY-12326), characterized by the substitution of diaminopurine. Cyclic-di-DAP is used as a specialized tool in biochemical research to detect nucleotide-binding sites related to bacterial second messengers, RNA riboswitches, and cellular signaling pathways .
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