1. Cell Cycle/DNA Damage
  2. DNA/RNA Synthesis
  3. Nusinersen

Nusinersen 

Cat. No.: HY-112980
Handling Instructions

Nusinersen is an antisense oligonucleotide drug that modifies pre–messenger RNA splicing of the SMN2 gene and thus promotes increased production of full-length SMN protein.

For research use only. We do not sell to patients.

Nusinersen Chemical Structure

Nusinersen Chemical Structure

CAS No. : 1258984-36-9

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Description

Nusinersen is an antisense oligonucleotide drug that modifies pre–messenger RNA splicing of the SMN2 gene and thus promotes increased production of full-length SMN protein[1].

In Vitro

Nusinersen is an SMN-ASO that increases SMN levels by blocking an intronic splice silencer in SMN2, thereby facilitating the exon 7 inclusion and generation of FL-SMN2 transcripts[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

CAS No.
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Nusinersen
Cat. No.:
HY-112980
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