5-Methylcytidine 5′-triphosphate
Based on 1 publication(s) in Google Scholar
5-Methylcytidine 5′-triphosphate (5-Methyl-CTP) is a modified ribonucleoside 5′-triphosphate. When incorporated into mRNA, 5-Methylcytidine 5′-triphosphate enhances the translation efficiency and stability of the mRNA, and reduces the innate immune response. 5-Methylcytidine 5′-triphosphate can be used in studies related to gene replacement and vaccination applications.
For research use only. We do not sell to patients.
- CAS No.: 327174-86-7
- Formula: C10H18N3O14P3
- Molecular Weight:497.18
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications Citing Use of MedChemExpress (MCE) 5-Methylcytidine 5′-triphosphate
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Biological Activity
Description
In Vitro
5-Methylcytidine 5′-triphosphate (trisodium) is efficiently synthesized via a protection-free one-pot three-step chemical method from 5-methylcytidine via monophosphorylation followed by reaction with pyrophosphate[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 327174-86-7
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Molecular Weight 497.18
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Formula C10H18N3O14P3
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SMILES
O[C@@H]1[C@H](O)[C@@H](COP(OP(OP(O)(O)=O)(O)=O)(O)=O)O[C@H]1N2C(N=C(N)C(C)=C2)=O
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Synonyms
5-Methyl-CTP
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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Cell Rep
Depletion of CUL4B in macrophages ameliorates diabetic kidney disease via miR-194-5p/ITGA9 axis. [Abstract]2023 May 23;42(6):112550. PMID: 37224018
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)