5-Methylcytidine 5′-triphosphate
Based on 1 publication(s) in Google Scholar
5-Methylcytidine 5′-triphosphate (5-Methyl-CTP) is a modified ribonucleoside 5′-triphosphate. When incorporated into mRNA, 5-Methylcytidine 5′-triphosphate enhances the translation efficiency and stability of the mRNA, and reduces the innate immune response. 5-Methylcytidine 5′-triphosphate can be used in studies related to gene replacement and vaccination applications.
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- CAS No.: 327174-86-7
- Formule: C10H18N3O14P3
- Masse moléculaire:497.18
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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- Pureté et documentation
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Help & FAQs
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HY-112582A
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HY-W013093
Uridine triphosphate trisodium saltUTP -
HY-107372H
UTP trisodium salt, 100 mM Solution, PCR GradeUTP -
HY-112582AGL
N1-Methylpseudouridine-5′-triphosphate (GMP like)Nucleobase-modified Nucleotide -
HY-W013093R
Uridine triphosphate trisodium salt (Standard)UTP -
HY-N11522
5-Methyluridine 5′-triphosphateUTP Analog -
HY-141567
Pseudouridine 5'-triphosphateUTP Derivative
Publications Citing Use of MedChemExpress (MCE) 5-Methylcytidine 5′-triphosphate
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Activité biologique
Description
In Vitro
5-Methylcytidine 5′-triphosphate (trisodium) is efficiently synthesized via a protection-free one-pot three-step chemical method from 5-methylcytidine via monophosphorylation followed by reaction with pyrophosphate[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 327174-86-7
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Masse moléculaire 497.18
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Formule C10H18N3O14P3
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SMILES
O[C@@H]1[C@H](O)[C@@H](COP(OP(OP(O)(O)=O)(O)=O)(O)=O)O[C@H]1N2C(N=C(N)C(C)=C2)=O
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Synonyms
5-Methyl-CTP
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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Cell Rep
Depletion of CUL4B in macrophages ameliorates diabetic kidney disease via miR-194-5p/ITGA9 axis. [Abstract]2023 May 23;42(6):112550. PMID: 37224018
Protocole
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RNA extraction experimental
By lysing cells, releasing RNA, and removing impurities such as proteins and DNA, high-purity RNA products are finally obtained. The commonly used traditional method is the guanidine isothiocyanate/phenol/chloroform method (Trizol), which is suitable for a variety of animal materials including animal tissues, microorganisms, cultured cells, etc., and most plant materials.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
5-Methylcytidine 5′-triphosphate Related Classifications
HY-147338 Related Classifications
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