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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
178 Results for "
monooxygenase
" in MedChemExpress (MCE) Product Catalog:
Products (178)
178 Results for "monooxygenase" in MCE Product Catalog:
2
2 Cited Publications
Target:
Research Areas:
GSK180 is a selective, competitive, and potent inhibitor of kynurenine-3-monooxygenase (KMO), a key enzyme of tryptophan metabolism (IC50, ~6 nM), but shows negligible activity against other enzymes on the tryptophan pathway. GSK180 rapidly changes levels of kynurenine pathway metabolites, and acts as a useful tool to probe the therapeutic potential of KMO inhibition .
2
2 Cited Publications
Cat. No.: HY-P81223
Synonyms: Cholesterol 20 22 desmolase antibody
Cholesterol desmolase antibody;
Cholesterol monooxygenase (side chain cleaving) antibody;
Cholesterol side chain cleavage enzyme antibody;
Cholesterol side chain cleavage enzyme mitochondrial antibody;
Cholesterol side-chain cleavage enzyme antibody;
CP11A_HUMAN antibody;
CYP11A antibody;
CYP11A1 antibody;
CYPXIA1 antibody;
Cytochrome P450 11A1 antibody;
Cytochrome P450 11A1 mitochondrial antibody;
Cytochrome P450 family 11 subfamily A polypeptide 1 antibody;
Cytochrome P450 subfamily XIA antibody;
Cytochrome P450(scc) antibody;
Cytochrome P450C11A1 antibody;
mitochondrial antibody;
P450SCC antibody;
Steroid 20 22 lyase antibody;
1
1 Cited Publications
Cat. No.: HY-W015635
CAS No.: 2179-57-9
1
1 Cited Publications
Target:
Research Areas:
UPF-648 is a potent kynurenine 3-monooxygenase (KMO) inhibitor; exhibits highly active at 1 uM (81 ± 10% KMO inhibition); ineffective at blocking KAT activity.
1
1
1 Cited Publications
Cat. No.: HY-P73733
Purity: ≥ 95%, as determined by reducing SDS-PAGE or Bis-Tris PAGE.
Synonyms: PAH; PH; Phenylalanine Hydroxylase; L-Phenylalanine Hydroxylase; Phenylalanine-4-Hydroxylase; PAH Protein; Phe-4-monooxygenase; PKU1; Phenylalanine 4-monooxygenase; PKU
Species:
Source:
Cat. No.: HY-W327449
CAS No.: 501-13-3
Category:
Target:
Cat. No.: HY-W338852
CAS No.: 25351-24-0
Target:
Research Areas:
Gentisuric acid, a metabolite of Aspirin (HY-14654), is a substrate of α-amidating monooxygenase (PAM). Gentisuric acid prevents DNA-damage by Mitomycin C (HY-13316) .
Cat. No.: HY-W009247
CAS No.: 161696-76-0
Synonyms: N-Demethylolanzapine; LY170055
Target:
Research Areas:
N-Desmethylolanzapine is an antipsychotic drug.
The formation of N-Desmethylolanzapine correlates with the level and activity
of human liver flavin-containing monooxygenase (FMO3). N-Desmethylolanzapine
can be used in the study of antipsychotic drugs .
Cat. No.: HY-138126
CAS No.: 113527-49-4
Cat. No.: HY-W015464
CAS No.: 16284-60-9
Cat. No.: HY-W019334
CAS No.: 202842-98-6
Synonyms: 3,4-DMPP
3,4-Dimethylpyrazole phosphate (3,4-DMPP) is a nitrification inhibitor and microbial community regulator, whose activity is dose- and soil pH-dependent. 3,4-Dimethylpyrazole phosphate inhibits ammonia monooxygenase, ammonia-oxidizing bacteria, as well as ammonia-oxidizing archaea and nitrite-oxidizing bacteria. 3,4-Dimethylpyrazole phosphate alters the community composition of prokaryotes, fungi and ammonia-oxidizing bacteria. 3,4-Dimethylpyrazole phosphate reduces nitrate leaching, nitrous oxide emission and soil nitrate accumulation, and enhances nitrogen use efficiency and crop yield in agricultural production. 3,4-Dimethylpyrazole phosphate is applicable to agriculture-related research .
Cat. No.: HY-W007410
CAS No.: 1550-35-2
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Research Areas:
2,4-Difluorobenzaldehyde is a fluorinated benzaldehyde derivative commonly used as an intermediate in organic synthesis. 2,4-Difluorobenzaldehyde serves as a substrate for enzymatic oxidation and undergoes the Baeyer-Villiger oxidation reaction under the catalysis of 4-hydroxyacetophenone monooxygenase. 2,4-Difluorobenzaldehyde acts as a synthetic precursor for trichalcone enzyme inhibitors. 2,4-Difluorobenzaldehyde is applicable to related research in fields such as medicine, pesticides, and liquid crystal materials .
Cat. No.: HY-170920
CAS No.: 3056059-99-2
Research Areas:
Herbicide safener-4 is a herbicide safener targeting acetolactate synthase (ALS). Herbicide safener-4 competitively binds to the active site of ALS, blocks the binding of Mesosulfuron-methyl (HY-126987), and simultaneously allows substrates to enter for catalytic reactions. Herbicide safener-4 increases the content/activity of glutathione (GSH), glutathione S-transferase (GST), cytochrome P450 monooxygenase (CYP450) and peroxidase (POD) in plants, and decreases the activity of superoxide dismutase (SOD) .
Cat. No.: HY-N11425
CAS No.: 36504-71-9
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Target:
Research Areas:
Propiolamide is a monooxygenase (MMO) system activator and glutathione peroxidase 4 (GPX4) inhibitor. Propiolamide induces ROS production through interaction with the MMO system. Propiolamide promotes the accumulation of intracellular cytotoxic lipid peroxides and induces ferroptosis. Propiolamide induces programmed cell death via the apoptosis pathway. Propiolamide can be used in cancer research .
Cat. No.: HY-138126A
CAS No.: 350691-68-8
Dansyl-Tyr-Val-Gly TFA is a substrate of peptidylglycine monooxygenase (PHM), with a KD of 22 μM for PHM. Dansyl-Tyr-Val-Gly TFA can be used to investigate the catalytic mechanism, kinetics and inactivation characteristics of PHM .
Cat. No.: HY-W327449R
CAS No.: 501-13-3
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Target:
Cat. No.: HY-15500
CAS No.: 1008119-83-2
Target:
Research Areas:
JM6 is a weak kynurenine 3-monooxygenase (KMO) inhibitor with an IC50 of 19.85 μM for mouse KMO. JM6 can be used for Alzheimer's diseases research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
