4 Results for "

mucopolysaccharidosis II

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "mucopolysaccharidosis II" in MCE Product Catalog:

Cat. No.: HY-P99797
CAS No.: 2140211-48-7
Synonyms: JR-141

Target:  

Transferrin Receptor

Research Areas:  

Neurological Disease

Pabinafusp alfa (JR-141) is a transferrin receptor-targeting antibody consisting of Iduronate 2-sulfatase (HY-P76399) and an anti-human transferrin receptor antibody. Pabinafusp alfa is blood-brain permeable and prevents heparan sulfate (HS) deposition in the central nervous system of mucopolysaccharidosis II (MPS II) mice. Pabinafusp alfa improves learning and prevents central nervous system neuronal damage in mice .
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Cat. No.: HY-P990724
CAS No.: 2641020-57-5
Synonyms: DNL-310

Target:  

Steroid Sulfatase

Research Areas:  

Metabolic Disease

Tividenofusp alfa (DNL‑310) is a modified iduronate‑2‑sulfatase fusion protein capable of crossing the blood-brain barrier. Tividenofusp alfa can be used in research on mucopolysaccharidosis type II .
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Cat. No.: HY-P991037
CAS No.: 2699034-69-8
Synonyms: GNR 055

Target:  

Steroid Sulfatase

Research Areas:  

Metabolic Disease

Verenafusp alfa (GNR 055) is a recombinant fusion protein of iduronate-2-sulfatase and a monoclonal antibody Fab fragment to human insulin receptor for distribution of the enzyme into brain. Verenafusp alfa can be used for the study of mucopolysaccharidosis type II (MPS II) .
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Cat. No.: HY-P992048
Synonyms: HIRMab; SHP-631; TAK-531

Target:  

Insulin Receptor

Research Areas:  

Metabolic Disease

AGT-182 (HIRMab; SHP-631; TAK-531) is a brain-penetrating anti-human insulin receptor antibody and iduronate-2-sulfatase conjugation. AGT-182 can be used for the research of mucopolysaccharidosis type II (MPS II, Hunter syndrome) .
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