3 Results for "

neuromuscular paralysis

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "neuromuscular paralysis" in MCE Product Catalog:

Cat. No.: HY-W127670
CAS No.: 1420-40-2
Decamethonium (iodide) is an organic compound containing ammonium and iodide ions. It is commonly used as a neuromuscular blocking agent in anesthesia to induce muscle relaxation during surgery. Decamethonium Iodide acts by binding to nicotinic acetylcholine receptors (nAChRs) in the neuromuscular junction, causing depolarization block and subsequent skeletal muscle paralysis. In addition, it can also serve as a reference standard for pharmacological studies of nAChRs.
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Cat. No.: HY-15308B
CAS No.: 110415-68-4
Research Areas:  

Neurological Disease

Δ²-Avermectin B₁ₐ (Compound 3) is an antiparasitic agent targeting glutamate-gated chloride channels (GluCls) in the neuromuscular system of invertebrates. Δ²-Avermectin B₁ₐ enhances chloride ion influx, leading to hyperpolarization of the neuromuscular cell membrane, inhibition of neural signal transmission, and ultimately paralysis and death of parasites. Δ²-Avermectin B₁ₐ is promising for research of agricultural pests .
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Cat. No.: HY-127147
CAS No.: 49564-56-9
Synonyms: AH 8165 bromide
Target:  

mAChR

Research Areas:  

Neurological Disease

Fazadinium bromide (AH 8165 bromide) is a species-specific neuromuscular blocking agent that primarily targets the acetylcholine receptor (AChR) at the skeletal neuromuscular junction, blocking the receptor agonist binding site in a competitive and reversible manner. Fazadinium bromide induces sustained tetanic fade, and tetanic contractions are more sensitive than single twitches. Fazadinium bromide can be used in anesthesia and research related to neuromuscular transmission .
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