1 Result for "

neuroprotective ,MCF-7

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "neuroprotective ,MCF-7" in MCE Product Catalog:

Cat. No.: HY-116377
CAS No.: 186303-55-9
Purity:  99.18%
Target:  

Steroid Sulfatase

Research Areas:  

Neurological Disease

DU-14 is a potent steroid sulfatase inhibitor with an IC50 of 55.8 nM. DU-14 inhibits the MCF-7 cell proliferation (IC50 = 38.7 nM). DU-14 has neuroprotective effects against neurotoxic Aβ, suggesting that up-regulation of endogenous DHEAS by DU-14 could be beneficial to the alleviation of Aβ-induced impairments in spatial memory and synaptic plasticity .
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