65 Results for "

oligopeptide

" in MedChemExpress (MCE) Product Catalog:
Products (65)

65 Results for "oligopeptide" in MCE Product Catalog:

6
6 Publications Verification
Cat. No.: HY-16969
CAS No.: 1401708-83-5
Synonyms: PNB-0408; N-hexanoic-Try-Ile-(6)-amino hexanoic amide; Hexanoyl-Tyr-Ile-Ahx-NH2
Target:  

c-Met/HGFR

Research Areas:  

Neurological Disease

Dihexa, an oligopeptide drug, is an orally active and blood-brain barrier-permeable angiotensin IV analog. Dihexa binds to hepatocyte growth factor (HGF) with high affinity (Kd=65 pM) and potentiates its activity at its receptor, c-Met. Dihexa exhibits excellent antidementia activity and improves cognitive function in animal models. Dihexa may have therapeutic potential as a treatment Alzheimer’s disease .
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1
1 Cited Publications
Cat. No.: HY-111956B
CAS No.: 2703746-41-0
Purity:  98.77%
Target:  

Fluorescent Dye

Research Areas:  

Cancer

D-Ala-Lys-AMCA hydrochloride is a known proton-coupled oligopeptide transporter 1 (PEPT1) substrate that emits blue fluorescence. D-Ala-Lys-AMCA hydrochloride may be transported into liver cancer cells and Caco-2 cells based on fluorescence analysis. D-Ala-Lys-AMCA hydrochloride can be used for characterizing PEPT1-specific substrates or inhibitors (Ex/Em = 390/480 nm) .
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Cat. No.: HY-P10294
CAS No.: 593266-60-5
Target:  

Amyloid-β

Research Areas:  

Others

Oligopeptide P11-4 is an α-peptide that can be self-assembled into β-sheet amyloids with a hydrogel appearance at low pH. Oligopeptide P11-4 can be used in biomimetic mineralization, enamel regeneration and oral care agent .
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Cat. No.: HY-P5255
CAS No.: 466691-40-7
Target:  

Bacterial

Research Areas:  

Infection Inflammation/Immunology

Oligopeptide-10 is a bioactive peptide with antimicrobial activity. Oligopeptide-10 exhibits broad-spectrum bactericidal effects against Gram-positive bacteria including Propionibacterium acnes and Staphylococcus aureus. Oligopeptide-10 targets lipoteichoic acid (LTA) on the surface of bacterial cell membranes, induces bacterial osmotic imbalance by disrupting the integrity of bacterial membranes, and reduces the release of pro-inflammatory cytokines induced by bacteria. Oligopeptide-10 possesses skin-protective activity. Oligopeptide-10 can be applied in research related to acne vulgaris, dandruff, seborrheic dermatitis, and tinea pedis .
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Cat. No.: HY-106279
CAS No.: 503844-09-5
Purity:  99.92%
Target:  

GnRH Receptor

Research Areas:  

Inflammation/Immunology

EA-230 is a synthetic oligopeptide originally derived from beta-human chorionic gonadotropin (beta-hCG) lysates. EA-230 has anti-inflammatory effects and can be used for the research of sepsis .
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Cat. No.: HY-W010162
CAS No.: 1948-31-8
Synonyms: L-Alanyl-L-alanine; Ala-Ala
H-Ala-Ala-OH is a substrate of human intestinal oligopeptide transporter (PEPT1/SLC15A1), with an IC50 of 0.25 mM and an EC50 of 0.08 mM against human PEPT1. When used as a dipeptide linker in antibody-drug conjugates (ADCs) loaded with glucocorticoid receptor regulator payloads, H-Ala-Ala-OH enables efficient intracellular payload release .
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Cat. No.: HY-107130
CAS No.: 725715-18-4
Purity:  99.73%
Synonyms: GM604
Target:  

Peptides

Research Areas:  

Neurological Disease

Alirinetide (GM604) is an oligopeptide containing 6 amino acids. Alirinetide can cross the blood-brain barrier and can be used for the research of multiple neurodegenerative diseases .
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Cat. No.: HY-P5251
CAS No.: 1206525-47-4
Research Areas:  

Metabolic Disease

Oligopeptide-68 is a bioactive peptide with anti-aging effect and has been reported used as a cosmetic ingredient .
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Cat. No.: HY-W142467
CAS No.: 637-84-3
Research Areas:  

Others

Tetraglycine is a oligopeptide composed of four glycine monomers .
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Cat. No.: HY-N10477
CAS No.: 31106-03-3
Synonyms: L-γ-Glutamyl-L-arginine; γ-Glu-Arg
gamma-Glutamylarginine (L-γ-Glutamyl-L-arginine), an γ-glutamic acid oligopeptide, can be isolated from Panax ginseng .
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Cat. No.: HY-D1154
CAS No.: 180342-52-3
β-Ala-Lys (AMCA) is a fluorescently labeled substrate of oligopeptide transporters . β-Ala-Lys (AMCA) acts as a substrate for a variety of bacterial proton-coupled oligopeptide transporters, and is used to label the activity of oligopeptide transporters. Excitation/emission wavelength: 340 nM/460 nM .
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Cat. No.: HY-126584
CAS No.: 3918-94-3
Purity:  ≥99.0%
Synonyms: Val-Val
Research Areas:  

Others

H-Val-Val-OH (Val-Val) is a stereochemistry-dependent substrate and inhibitor of apical oligopeptide transporters. H-Val-Val-OH undergoes apical intracellular accumulation in human intestinal cells via carrier-mediated transport, and inhibits the uptake of Cephalexin (HY-B0200) through interaction with transporters. Substitution of L-valine with D-valine in H-Val-Val-OH abolishes its binding ability to apical oligopeptide transporters .
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Cat. No.: HY-P0096
CAS No.: 137665-91-9
Target:  

Tyrosinase Sirtuin

Decapeptide-12, a small oligopeptide, is a tyrosinase inhibitor that interacts with C-terminal residue of tyrosinase (Kd: 61.1 μM). Decapeptide-12 is a competitive inhibitor of mushroom tyrosinase (IC50: 40 μM). Decapeptide-12 also increases transcription of SIRT. Decapeptide-12 reduces melanin content in melanocytes. Decapeptide-12 is used for the research of melanogenesis, senescence, inflammation .
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Cat. No.: HY-172275A
DSPE-PEG2000-pPB is a PEG compound which composed of DSPE and a cyclic oligopeptide (pPB). pPB has a strong binding affinity with PDGFRβ, which is overexpressed on activated hepatic stellate cells (HSC). DSPE-PEG2000-pPB can be used for drug delivery .
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Cat. No.: HY-P5259
Target:  

Peptides

Research Areas:  

Metabolic Disease

Oligopeptide-6 is a bioactive peptide with moisturizing effect and has been reported used as a cosmetic ingredient .
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Cat. No.: HY-P5257
CAS No.: 1018685-16-9
Synonyms: CG-EDP3
Target:  

Peptides

Research Areas:  

Others

Oligopeptide-24 (CG-EDP3) is a 13 amino acids biomimetic peptide with skin repair effect. Oligopeptide-24 upregulates expression of elastin and hyaluronic acid, and increases fibroblast activity. Oligopeptide-24 can be used in cosmetics as an anti-wrinkle and firming agent .
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Cat. No.: HY-P1973
CAS No.: 63775-95-1
Target:  

Peptides

Research Areas:  

Inflammation/Immunology

Cyclosporin B is a group of nonpolar cyclic oligopeptides with immunosuppressive activity. Cyclosporin B is used for the prevention of graft rejection in organ transplantation .
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Cat. No.: HY-111956
CAS No.: 375822-19-8
Target:  

Fluorescent Dye

Research Areas:  

Cancer

D-Ala-Lys-AMCA is a known proton-coupled oligopeptide transporter 1 (PEPT1) substrate that emits blue fluorescence. D-Ala-Lys-AMCA may be transported into liver cancer cells and Caco-2 cells based on fluorescence analysis. D-Ala-Lys-AMCA can be used for characterizing PEPT1-specific substrates or inhibitors (Ex/Em = 390/480 nm) .
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Cat. No.: HY-P5256
CAS No.: 948884-07-9
Target:  

Bacterial

Research Areas:  

Others

Oligopeptide-20 is a bioactive peptide with skin repair effect and has been reported used as a cosmetic ingredient .
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Cat. No.: HY-P4160
CAS No.: 634586-40-6
Synonyms: THG113.31; ILGHXDYK
Research Areas:  

Endocrinology

PDC31 (THG113.31; ILGHXDYK) is an allosteric and non-competitive inhibitor of FP Prostaglandin Receptor. PDC31 is the D-amino acid-based oligopeptide, is used for smooth muscle contractile agent. PDC31 decreases the strength and duration of uterine contractions in vivo, which can be used for research of preterm labor and primary dysmenorrhea (PD). PDC31 also enhances Ca 2+-dependent large-conductance K +-channel in human myometrial cells .
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