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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
33 Results for "
oxidizable substrate
" in MedChemExpress (MCE) Product Catalog:
Products (33)
33 Results for "oxidizable substrate" in MCE Product Catalog:
51
51 Publications Verification
Cat. No.: HY-B0445A
CAS No.: 20111-18-6
Synonyms: β-DPN sodium; β-NAD sodium; β-Nicotinamide Adenine Dinucleotide sodium
25
25 Cited Publications
Target:
Research Areas:
Cardiovascular Disease Neurological Disease Endocrinology Cancer
IU1 is a selective, reversible USP14 inhibitor with an IC50 of 4-5 μM. IU1 binds USP14’s catalytic cleft to block deubiquitinase activity. IU1 induces calpain-dependent Tau cleavage, causes ATP deficits, reduces E1~Ub thioester levels and 26S proteasome assembly. IU1 enhances 26S proteasome chymotrypsin-like activity, modulates LC3B-dependent autophagy flux, reduces cancer cell proliferation and migration, and blocks G0/G1 to S phase cell cycle transition in follicular thyroid cancer cells. IU1 activates autophagy-lysosomal and ubiquitin-proteasome pathways, triggers apoptosis, and reduces cervical cancer cell growth. IU1 enhances degradation of proteasome substrates linked to neurodegenerative disease, accelerates oxidized protein degradation, and increases oxidative stress resistance. IU1 can be used for the research of Alzheimer’s disease, follicular thyroid cancer, ischemic stroke, cervical cancer, and neurodegenerative disease .
1
1 Cited Publications
Synonyms: 2'-Deoxyguanosine-5'-triphosphate
Cat. No.: HY-W012241
CAS No.: 693-23-2
Target:
Synonyms: Bluo-Gal
Target:
Research Areas:
5-Bromo-3-indolyl β-D-galactopyranoside (Bluo-Gal) is a chromogenic substrate for β-galactosidase. 5-Bromo-3-indolyl β-D-galactopyranoside is hydrolyzed by the enzyme to generate a 5-bromoindole intermediate, which is further oxidized to form an insoluble blue precipitate. 5-Bromo-3-indolyl β-D-galactopyranoside can specifically recognize bacterial β-galactosidases (such as the product of the Escherichia coli lacZ gene) and reacts at pH 7.4, making it suitable for light and electron microscopic observations. 5-Bromo-3-indolyl β-D-galactopyranoside can be used in histochemical detection of reporter gene expression in transgenic organisms, such as the localization analysis of β-galactosidase activity in mouse embryos or muscle tissues .
Cat. No.: HY-W012145
CAS No.: 637-01-4
Target:
Research Areas:
TMPD dihydrochloride, a readily oxidizable compound, is an enzymatically convert redox active substrate molecule. TMPD dihydrochloride is also an electron donor and serves as a reducing cosubstrate for heme peroxidases . TMPD dihydrochloride is also a complex IV substrate .
Category:
Ketones, Aldehydes, Acids Other Diseases Phenols Polyphenols Endogenous metabolite Disease Research Fields
Target:
Cat. No.: HY-W002251
CAS No.: 5381-20-4
Cat. No.: HY-W015777
CAS No.: 105-13-5
Synonyms: P-Methoxy-benzyl alcoho; (4-Methoxyphenyl)methanol
Cat. No.: HY-112817
CAS No.: 139307-94-1
Synonyms: 8-Oxo-Deoxyguanosine triphosphate
Category:
Target:
Research Areas:
L-Mannitol is a synthetic L-configured acyclic sugar alcohol. L-Mannitol scavenges free radicals, reduces injection-related inflammation and swelling, and inhibits hyaluronic acid degradation. L-Mannitol can be oxidized as a substrate to L-fructose. L-Mannitol serves as a pharmaceutical excipient and can be used in relevant research in the food and pharmaceutical fields .
Cat. No.: HY-B0445AR
CAS No.: 20111-18-6
Synonyms: β-DPN sodium (Standard); β-NAD sodium (Standard); β-Nicotinamide Adenine Dinucleotide sodium (Standard)
Cat. No.: HY-W012241S1
CAS No.: 97543-02-7
Cat. No.: HY-W012241R
CAS No.: 693-23-2
Cat. No.: HY-131597
CAS No.: 21238-36-8
Synonyms: 8-Hydroxyguanosine triphosphate
Category:
Target:
Cat. No.: HY-D1740
CAS No.: 105284-17-1
Synonyms: DHTM Ros
Cat. No.: HY-W012241S
CAS No.: 89613-32-1
Cat. No.: HY-W777762
CAS No.: 1173019-20-9
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
