Benzo[b]thiophene-3-carbaldehyde
Based on 1 Customer Validation
Benzo[b]thiophene-3-carbaldehyde is a 3-formyl-substituted benzo[b]thiophene derivative that acts as an oxidizable substrate to convert to benzo[b]thiophene-3-carboxylic acid under liquid-phase conditions. Compared with analogs such as benzaldehyde and thiophene-2-carbaldehyde, Benzo[b]thiophene-3-carbaldehyde has lower oxidation difficulty, and can significantly increase the reaction rate in the presence of initiators (such as Na+Br- or DBA). Benzo[b]thiophene-3-carbaldehyde also serves as a key starting material for the synthesis of compounds including heteroaryl chalcones.
For research use only. We do not sell to patients.
- Purity: 98.71%
- CAS No.: 5381-20-4
- Formula: C9H6OS
- Molecular Weight:162.21
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Storage:
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
![Benzo[b]thiophene-3-carbaldehyde Chemical Structure](https://file.medchemexpress.com/product_pic/hy-w002251.gif "Click to View Benzo[b]thiophene-3-carbaldehyde Chemical Structure")
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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HY-B0973R
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HY-20379
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HY-W004615
Thiophene-3-carboxylic acid
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HY-W001968
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Biological Activity
Benzo[b]thiophene-3-carbaldehyde (0.518 M; 60 h without initiator, 6 h with initiator NaBr or DBA) is readily oxidized to benzo[b]thiophene-3-carboxylic acid, with initiators (NaBr or DBA) drastically reducing reaction time from 60 h to 6 h at a concentration of 0.518 M[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 5381-20-4
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Appearance Solid
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Molecular Weight 162.21
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Formula C9H6OS
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Color Yellow to brown
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SMILES
O=CC1=CSC2=CC=CC=C12
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
DMSO : 100 mg/mL (616.48 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 6.1648 mL | 30.8242 mL | 61.6485 mL | 154.1212 mL |
| 5 mM | 1.2330 mL | 6.1648 mL | 12.3297 mL | 30.8242 mL | |
| 10 mM | 0.6165 mL | 3.0824 mL | 6.1648 mL | 15.4121 mL | |
| 15 mM | 0.4110 mL | 2.0549 mL | 4.1099 mL | 10.2747 mL | |
| 20 mM | 0.3082 mL | 1.5412 mL | 3.0824 mL | 7.7061 mL | |
| 25 mM | 0.2466 mL | 1.2330 mL | 2.4659 mL | 6.1648 mL | |
| 30 mM | 0.2055 mL | 1.0275 mL | 2.0549 mL | 5.1374 mL | |
| 40 mM | 0.1541 mL | 0.7706 mL | 1.5412 mL | 3.8530 mL | |
| 50 mM | 0.1233 mL | 0.6165 mL | 1.2330 mL | 3.0824 mL | |
| 60 mM | 0.1027 mL | 0.5137 mL | 1.0275 mL | 2.5687 mL | |
| 80 mM | 0.0771 mL | 0.3853 mL | 0.7706 mL | 1.9265 mL | |
| 100 mM | 0.0616 mL | 0.3082 mL | 0.6165 mL | 1.5412 mL |
Benzo[b]thiophene-3-carbaldehyde Related Classifications
HY-W002251 Related Classifications
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