63-84-3
Chemical Structure
DL-Dopa
- CAS 番号: 63-84-3
- Formula:C9H11NO4
- Molecular Weight:197.19
IUPAC Name: 2-amino-3-(3,4-dihydroxyphenyl)propanoic acid
InChIKey: WTDRDQBEARUVNC-UHFFFAOYSA-N
SMILES: NC(CC1=CC=C(O)C(O)=C1)C(O)=O
Biological Activity: DL-Dopa is a dopamine precursor. It serves as a substrate for Mushroom Tyrosinase, which oxidizes it to dopaquinone, an intermediate in the DOPA-melanin polymerization process, and this reaction can be detected at 475 nm. DL-Dopa also forms synergistic hydrophobic and π-π stacking interactions with cationic surfactants. Its binding to cetylpyridinium chloride (HY-B1464) is stronger and exhibits better thermodynamic stability than its binding to benzalkonium chloride (HY-B2232). DL-Dopa can compensate for dopamine depletion in the brain and is applicable to research related to Parkinson's disease[1][2].
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DL-Dopa | 98.58% | DL-Dopa is a dopamine precursor. It serves as a substrate for Mushroom Tyrosinase, which oxidizes it to dopaquinone, an intermediate in the DOPA-melanin polymerization process, and this reaction can be detected at 475 nm. DL-Dopa also forms synergistic hydrophobic and π-π stacking interactions with cationic surfactants. Its binding to cetylpyridinium chloride (HY-B1464) is stronger and exhibits better thermodynamic stability than its binding to benzalkonium chloride (HY-B2232). DL-Dopa can compensate for dopamine depletion in the brain and is applicable to research related to Parkinson's disease. | ||||||||||||||||||||
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DL-Dopa-d6 | DL-Dopa-d6 is the deuterium labeled DL-Dopa. DL-Dopa is a beta-hydroxylated derivative of phenylalanine. | |||||||||||||||||||||
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L-Dopa-d3 | L-Dopa-d3 is deuterated labeled DL-Dopa (HY-113404). DL-Dopa is a beta-hydroxylated derivative of phenylalanine. | |||||||||||||||||||||
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References
- [1]. Kahn V, et al. Effect of kojic acid on the oxidation of DL-DOPA, norepinephrine, and dopamine by mushroom tyrosinase. Pigment Cell Res. 1995;8(5):234-240. [Content Brief]
- [2]. Elkaseh E M, et al. Physicochemical investigation of DL-DOPA interaction with cationic surfactants: Micellization, binding thermodynamics, and solubilization[J]. JCIS Open, 2026, 21: 100171.
