63-84-3
63-84-3
Chemical Structure
DL-Dopa
- CAS No.: 63-84-3
- Formula:C9H11NO4
- Molecular Weight:197.19
IUPAC Name: 2-amino-3-(3,4-dihydroxyphenyl)propanoic acid
InChIKey: WTDRDQBEARUVNC-UHFFFAOYSA-N
SMILES: NC(CC1=CC=C(O)C(O)=C1)C(O)=O
Biological Activity: DL-Dopa is a dopamine precursor. It serves as a substrate for Mushroom Tyrosinase, which oxidizes it to dopaquinone, an intermediate in the DOPA-melanin polymerization process, and this reaction can be detected at 475 nm. DL-Dopa also forms synergistic hydrophobic and π-π stacking interactions with cationic surfactants. Its binding to cetylpyridinium chloride (HY-B1464) is stronger and exhibits better thermodynamic stability than its binding to benzalkonium chloride (HY-B2232). DL-Dopa can compensate for dopamine depletion in the brain and is applicable to research related to Parkinson's disease[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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DL-Dopa | 98.58% | DL-Dopa is a dopamine precursor. It serves as a substrate for Mushroom Tyrosinase, which oxidizes it to dopaquinone, an intermediate in the DOPA-melanin polymerization process, and this reaction can be detected at 475 nm. DL-Dopa also forms synergistic hydrophobic and π-π stacking interactions with cationic surfactants. Its binding to cetylpyridinium chloride (HY-B1464) is stronger and exhibits better thermodynamic stability than its binding to benzalkonium chloride (HY-B2232). DL-Dopa can compensate for dopamine depletion in the brain and is applicable to research related to Parkinson's disease. | ||||||||||||||||||||
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DL-Dopa-d6 | DL-Dopa-d6 is the deuterium labeled DL-Dopa. DL-Dopa is a beta-hydroxylated derivative of phenylalanine. | |||||||||||||||||||||
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L-Dopa-d3 | L-Dopa-d3 is deuterated labeled DL-Dopa (HY-113404). DL-Dopa is a beta-hydroxylated derivative of phenylalanine. | |||||||||||||||||||||
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L-DOPA (Standard) | 99.86% | L-DOPA (Standard) is the analytical standard of L-DOPA. This product is intended for research and analytical applications. L-DOPA (Levodopa) is an orally active metabolic precursor of neurotransmitters dopamine. L-DOPA can cross the blood-brain barrier and is converted into dopamine in the brain. L-DOPA has anti-allodynic effects and the potential for Parkinson's disease. | ||||||||||||||||||||
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L-DOPA-13C6 | 99.11% | L-DOPA-13C6 is the 13C-labled L-DOPA. L-DOPA (Levodopa) is an orally active metabolic precursor of neurotransmitters dopamine. L-DOPA can cross the blood-brain barrier and is converted into dopamine in the brain. L-DOPA has anti-allodynic effects and the potential for Parkinson's disease. | ||||||||||||||||||||
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L-DOPA-13C | 99.77% | L-DOPA-13C is the 13C labeled L-DOPA. L-DOPA (Levodopa) is an orally active metabolic precursor of neurotransmitters dopamine. L-DOPA can cross the blood-brain barrier and is converted into dopamine in the brain. L-DOPA has anti-allodynic effects and the potential for Parkinson's disease. | ||||||||||||||||||||
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H-Tyr(3-I)-OH | 99.79% | H-Tyr(3-I)-OH is a potent and effective tyrosine hydroxylase inhibitor. H-Tyr(3-I)-OH is an intermediate in the production of thyroid hormones and has a role as a human or mouse metabolite. | ||||||||||||||||||||
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H-Tyr(3-I)-OH-13C6 | H-Tyr(3-I)-OH-13C6 is the 13C-labeled H-Tyr(3-I)-OH. H-Tyr(3-I)-OH is a potent and effective tyrosine hydroxylase inhibitor. H-Tyr(3-I)-OH is an intermediate in the production of thyroid hormones and has a role as a human or mouse metabolite. | |||||||||||||||||||||
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3-Fluoro-DL-tyrosine | 98.0% | 3-Fluoro-DL-tyrosine is a tyrosine derivative. | ||||||||||||||||||||
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3-Bromo-L-tyrosine | 98.74% | 3-Bromo-L-tyrosine (3-Bromo-Tyr) is a tyrosine derivative. | ||||||||||||||||||||
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3-Bromo-L-tyrosine-13C9 | 3-Bromo-L-tyrosine-13C9 (3-Bromo-Tyr-13C9) is 13C-labeled 3-?Bromo-?L-?tyrosine (HY-W018386). | |||||||||||||||||||||
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D-Dopa | 99.67% | D-Dopa (3-Hydroxy-D-tyrosine) is a potent, orally active, non-competitive and allosteric inhibitor of glutamate carboxypeptidase II (GCPII) with an IC50 of 200 nM. D-Dopa elevates brain dopamine and produce turning behavior in rats. D-Dopa inhibit severe fever with thrombocytopenia syndrome (SFTS) virus infection. D-Dopa can be used for neurological disease and virus infection research. | ||||||||||||||||||||
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4-Amino-3-hydroxyphenylalanine | 4-Amino-3-hydroxyphenylalanine dihydrochloride (4-AHP) is a photodegradation product of eumelanin. 4-Amino-3-hydroxyphenylalanine dihydrochloride can be used to investigate the development of cutaneous melanoma and age-related macular degeneration. | |||||||||||||||||||||
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References
- [1]. Kahn V, et al. Effect of kojic acid on the oxidation of DL-DOPA, norepinephrine, and dopamine by mushroom tyrosinase. Pigment Cell Res. 1995;8(5):234-240. [Content Brief]
- [2]. Elkaseh E M, et al. Physicochemical investigation of DL-DOPA interaction with cationic surfactants: Micellization, binding thermodynamics, and solubilization[J]. JCIS Open, 2026, 21: 100171.
