693-23-2
693-23-2
Chemical Structure
Dodecanedioic acid
- CAS No.: 693-23-2
- Formula:C12H22O4
- Molecular Weight:230.30
IUPAC Name: dodecanedioic acid
InChIKey: TVIDDXQYHWJXFK-UHFFFAOYSA-N
SMILES: OC(=O)CCCCCCCCCCC(O)=O
Biological Activity: Dodecanedioic acid is an orally active straight-chain dicarboxylic acid. As an alternative energy substrate between lipids and carbohydrates, Dodecanedioic acid can be rapidly oxidized during exercise, reducing muscle fatigue without stimulating insulin secretion. Dodecanedioic acid also exhibits blood glucose-lowering activity in non-insulin-dependent diabetes mellitus[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Dodecanedioic acid | 98.0% | Dodecanedioic acid is an orally active straight-chain dicarboxylic acid. As an alternative energy substrate between lipids and carbohydrates, Dodecanedioic acid can be rapidly oxidized during exercise, reducing muscle fatigue without stimulating insulin secretion. Dodecanedioic acid also exhibits blood glucose-lowering activity in non-insulin-dependent diabetes mellitus. | ||||||||||||||||||||
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Dodecanedioic acid (Standard) | 99.94% | Dodecanedioic acid (Standard) is the analytical standard of Dodecanedioic acid (HY-W012241). This product is intended for research and analytical applications. Dodecanedioic acid is an orally active straight-chain dicarboxylic acid. As an alternative energy substrate between lipids and carbohydrates, Dodecanedioic acid can be rapidly oxidized during exercise, reducing muscle fatigue without stimulating insulin secretion. Dodecanedioic acid also exhibits blood glucose-lowering activity in non-insulin-dependent diabetes mellitus. | ||||||||||||||||||||
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Dodecanedioic acid-d4 | 99.95% | Dodecanedioic acid-d4 is the deuterium labeled Dodecanedioic acid (HY-W012241). Dodecanedioic acid is an orally active straight-chain dicarboxylic acid. As an alternative energy substrate between lipids and carbohydrates, Dodecanedioic acid can be rapidly oxidized during exercise, reducing muscle fatigue without stimulating insulin secretion. Dodecanedioic acid also exhibits blood glucose-lowering activity in non-insulin-dependent diabetes mellitus. | ||||||||||||||||||||
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Dodecanedioic Acid-13C12 | Dodecanedioic Acid-13C12 is the 13C-labeled Dodecanedioic acid (HY-W012241). Dodecanedioic acid is an orally active straight-chain dicarboxylic acid. As an alternative energy substrate between lipids and carbohydrates, Dodecanedioic acid can be rapidly oxidized during exercise, reducing muscle fatigue without stimulating insulin secretion. Dodecanedioic acid also exhibits blood glucose-lowering activity in non-insulin-dependent diabetes mellitus. | |||||||||||||||||||||
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Dodecanedioic acid-d20 | 99.0% | Dodecanedioic acid-d20 is the deuterium labeled Dodecanedioic acid (HY-W012241). Dodecanedioic acid is an orally active straight-chain dicarboxylic acid. As an alternative energy substrate between lipids and carbohydrates, Dodecanedioic acid can be rapidly oxidized during exercise, reducing muscle fatigue without stimulating insulin secretion. Dodecanedioic acid also exhibits blood glucose-lowering activity in non-insulin-dependent diabetes mellitus. | ||||||||||||||||||||
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Tridecanedioic acid (Standard) | 99.93% | Tridecanedioic acid (Standard) is the analytical standard of Tridecanedioic acid (HY-128421). This product is intended for research and analytical applications. Tridecanedioic acid is an endogenous metabolite. Tridecanedioic acid is an endogenous metabolite. Tridecanedioic acid is related to the metabolic regulation of non-alcoholic fatty liver disease (NASH) and may be an important node molecule in the intestinal microbiota-host metabolism interaction network. Tridecanedioic acid is significantly accumulated in tolerant cabbage-type rapeseed varieties and has a lower content in sensitive varieties. It plays an important role in the defense response against the infection of the small cabbage moth (Plutella xylostella). Tridecanedioic acid can be used as a biomarker for plant insect resistance or a diagnostic marker for metabolic diseases. | ||||||||||||||||||||
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7-Hexadecenedioic acid | 7-Hexadecenedioic acid is an asymmetric olefinic aliphatic α,ω-dicarboxylic acid. When 7-Hexadecenedioic acid undergoes esterification with n-butanol under catalysis by PPL, it produces a 1:1 mixture of its two monobutyl ester isomers. | |||||||||||||||||||||
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Pentadecanedioic acid | 98.0% | Pentadecanedioic acid (1,13-Tridecanedicarboxylic acid) is an ester product. | ||||||||||||||||||||
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Tetradecanedioic acid (Standard) | ≥98% | Tetradecanedioic acid (Standard) is the analytical standard of Tetradecanedioic acid. This product is intended for research and analytical applications. Tetradecanedioic acid is an endogenous metabolite and belongs to the class of organic compounds known as long-chain fatty acids. Tetradecanedioic acid is an endogenous biomarker for assessing the activity of organic anion transporting polypeptides (OATPs). | ||||||||||||||||||||
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Decanedioic acid ammonium | Decanedioic acid (ammonium) (Sebacic acid (ammonium); Ammonium decanedioate; Diammonium sebacate) is a PROTAC linker that can be used in the synthesis of PROTACs. | |||||||||||||||||||||
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Hexadecanedioic acid | 98.0% | Hexadecanedioic acid (Thapsic acid) is an orally active metabolite produced by B. uniformis. Hexadecanedioic acid inhibits IRE1α-XBP1s-mediated flipogenesis and ferroptosis. Hexadecanedioic acid downregulates XBP1 and Hrd1 expression, activates the Nrf2/SLC7A11/GPX4 pathway. Hexadecanedioic acid can be used for the research of metabolic-associated fatty liver disease. | ||||||||||||||||||||
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Heptadecanedioic acid | ≥97.0% | Heptadecanedioic acid is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||||||||||||||||||
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12-Methoxy-12-oxododecanoic acid | 12-Methoxy-12-oxododecanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs. | |||||||||||||||||||||
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13-Methoxy-13-oxotridecanoic acid | 13-Methoxy-13-oxotridecanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs. | |||||||||||||||||||||
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References
- [1]. Greco AV, et al. The metabolic effect of dodecanedioic acid infusion in non-insulin-dependent diabetic patients. Nutrition. 1998 Apr;14(4):351-7. [Content Brief]
- [2]. Greco AV, et al. Uptake of dodecanedioic acid by isolated rat liver. Clin Chim Acta. 1997 Feb 17;258(2):209-18. [Content Brief]
- [3]. Salinari S, et al. Dodecanedioic acid overcomes metabolic inflexibility in type 2 diabetic subjects. Am J Physiol Endocrinol Metab. 2006 Nov;291(5):E1051-8. [Content Brief]
