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p,p'-DDE (Standard)

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  • HY-B1986R

    4,4'-DDE (Standard); p,p'-Dichlorodiphenyldichloroethylene (Standard)

    Reference Standards Androgen Receptor Drug Metabolite Metabolic Disease Endocrinology
    p,p'-DDE (Standard) is the analytical standard of p,p'-DDE. This product is intended for research and analytical applications. p,p'-DDE (4,4'-DDE) is the major and persistent metabolite of DDT. p,p'-DDE is a orally active androgen receptor antagonist with an IC50 of 5 μM and a Ki of 3.5 μM. p,p'-DDE can affect the development and function of the male reproductive system. Additionally, high serum concentrations of p,p'-DDE may be a risk factor for type 2 diabetes in women .
    p,p'-DDE (Standard)

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