11 Results for "

p-Tosylamide-d4

" in MedChemExpress (MCE) Product Catalog:
Products (11)

11 Results for "p-Tosylamide-d4" in MCE Product Catalog:

1
1 Cited Publications
Art. -Nr.: HY-P1103
CAS. Nr.: 1030384-98-5
Target:  

CXCR

Forschungsgebiete:  

Cancer

CTCE-9908 is a potent and selective CXCR4 antagonist. CTCE-9908 induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells .
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Art. -Nr.: HY-P4070
CAS. Nr.: 1188379-43-2
Target:  

Insulin Receptor

Forschungsgebiete:  

Metabolic Disease

Insulin icodec is an Insulin (HY-P0035) analog that strongly but reversibly binds to albumin. Insulin icodec has long plasma half-life. Insulin icodec modulates insulin receptor activity, controls blood glucose levels, reduces HbA1c levels, and binds reversibly to human serum albumin. Insulin icodec can be used for the research of type 2 diabetes mellitus .
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Art. -Nr.: HY-137798
CAS. Nr.: 88793-79-7
Target:  

Fluorescent Dye

Forschungsgebiete:  

Others

Chromozym PL is a chromogenic substrate for plasmin, and the enzymatic reaction can be carried out in 0.1mL Tris-HCl buffer (50 mM, pH 7.8). 100 μM Chromozym PL was dissolved and prepared. After adding the hydrolase, the generation of p-nitroaniline (pNA) at 405 nm was continuously observed, and the hydrolysis products were calculated .
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Art. -Nr.: HY-P1103A
Target:  

CXCR

Forschungsgebiete:  

Cancer

CTCE-9908 TFA is a potent and selective CXCR4 antagonist. CTCE-9908 TFA induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells .
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Art. -Nr.: HY-P11293
CAS. Nr.: 1309855-53-5
Target:  

Melanocortin Receptor

Forschungsgebiete:  

Cancer

DOTA-GGNle-CycMSHhex is a melanocortin-1 receptor (MC1R)-targeting peptide that can be radionuclide-labeled for melanoma imaging .
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Art. -Nr.: HY-P4757
CAS. Nr.: 108081-77-2
Target:  

Parasite

Forschungsgebiete:  

Others

N1-Glutathionyl-spermidine disulfide is a substrate of trypanothione reductase .
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Art. -Nr.: HY-P1321
CAS. Nr.: 158859-98-4
Synonyms: 1229U91; GW1229
Forschungsgebiete:  

Neurological Disease

GR231118, an analogue of the C-terminus of neuropeptide Y, is a potent , competitive and relative seletive antagonist at human neuropeptide Y Y receptor with a pKi of 10.4. GR231118 a potent agonist at the human neuropeptide Y Y4 receptor (pEC50=8.6; pKi=9.6) and a weak agonist at the human and rat neuropeptide YY2 and Y5 receptors. GR231118 also has high affinity for the mouse neuropeptide Y Y6 receptor (pKi= 8.8) .
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Art. -Nr.: HY-79602S
CAS. Nr.: 1219795-34-2
Synonyms: p-Tosylamide-d4
4-Tolyl-d4-sulfonamide (p-Tosylamide-d4) is the d4-labeled p-Toluenesulfonamide (HY-79602). p-Toluenesulfonamide is a small-molecule anticancer agent and plasticizer. p-Toluenesulfonamide exerts antitumor activity by inducing lysosomal membrane permeabilization, cathepsin B release and lysosome-mediated cell death. p-Toluenesulfonamide modulates cholesterol distribution in lipid rafts of tumor cell membranes and the Akt/mTOR/p70S6K pathway. p-Toluenesulfonamide shows activity against various cancers including hepatocellular carcinoma, non-small cell lung cancer and tongue squamous cell carcinoma; intrapleural injection effectively reduces malignant pleural effusion without causing pleural adhesion. p-Toluenesulfonamide is also the main degradation product of the disinfectant Chloramine-T (HY-B0959) in water. p-Toluenesulfonamide facilitates the localization of fluorescent probes to the endoplasmic reticulum. p-Toluenesulfonamide can be used in cancer-related research [4].
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Art. -Nr.: HY-P1321A
Synonyms: 1229U91 TFA; GW1229 TFA
Forschungsgebiete:  

Neurological Disease

GR231118 TFA, an analogue of the C-terminus of neuropeptide Y, is a potent , competitive and relative seletive antagonist at human neuropeptide YY receptor with a pKi of 10.4. GR231118 a potent agonist at the human neuropeptide YY4 receptor (pEC50=8.6; pKi=9.6) and a weak agonist at the human and rat neuropeptide Y Y2 and Y5 receptors. GR231118 also has high affinity for the mouse neuropeptide YY6 receptor (pKi= 8.8) .
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Art. -Nr.: HY-P11480
CAS. Nr.: 3105660-96-3
Target:  

Trk Receptor

Forschungsgebiete:  

Neurological Disease

TrkA/NGF-IN-1 (Peptide 19) is an inhibitor of protein-protein interactions between TrkA and NGF (IC50: 21 nM for human TrkA in PathHunter assay). TrkA/NGF-IN-1 shows an analgesic effect in a rat incisional pain model .
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Art. -Nr.: HY-P12133
CAS. Nr.: 3080063-21-1
Target:  

GLP Receptor

Forschungsgebiete:  

Metabolic Disease

Tapimtrutide is a gastric inhibitory polypeptide (GIP) and glucagon-like peptide 1 (GLP-1) receptor agonist. Tapimtrutide can be used for the research of diabetes .
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