3 Results for "

p38 MAPK-IN-7

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "p38 MAPK-IN-7" in MCE Product Catalog:

Cat. No.: HY-175429
CAS No.: 165806-50-8
Target:  

p38 MAPK

Research Areas:  

Inflammation/Immunology

p38 MAPK-IN-7 (Compound 2) is an orally active, potent and selective p38 MAP kinase inhibitor (IC50=170 nM). p38 MAPK-IN-7 is promising for research of inflammatory diseases such as rheumatoid arthritis and septic shock .
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Cat. No.: HY-162364
Target:  

p38 MAPK

Research Areas:  

Neurological Disease

p38-α MAPK-IN-7 (compound 4) is a p38α-MAPK inhibitor with an IC50 value of 98.7 nM. p38-α MAPK-IN-7 protects neuronal cells from dexamethasone-induced ROS production .
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Cat. No.: HY-N20744
CAS No.: 10387-49-2
Synonyms: Acetylumbelliferone
7-Acetoxycoumarin (Acetylumbelliferone) is an anti-inflammatory inhibitor with antibacterial and amoebicidal activities. 7-Acetoxycoumarin reduces the phosphorylation levels of ERK, JNK, NF-κB and p38 MAPK. 7-Acetoxycoumarin downregulates the protein and mRNA expression levels of iNOS and COX-2. 7-Acetoxycoumarin inhibits the production of IL-1β, IL-6, TNF-α, NO and PG2. 7-Acetoxycoumarin reduces the degradation of IκBα. 7-Acetoxycoumarin can be used in studies related to amoebiasis and Bacillus lentus infection .
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