23 Results for "

p50 subunit

" in MedChemExpress (MCE) Product Catalog:
Products (23)

23 Results for "p50 subunit" in MCE Product Catalog:

  • Targets Recommended:
16
16 Cited Publications
Cat. No.: HY-N0290
CAS No.: 4773-96-0
Mangiferin is a Nrf2 activator. Mangiferin suppresses nuclear translocation of the NF-κB subunits p65 and p50. Mangiferin exhibits antioxidant, antidiabetic, antihyperuricemic, antiviral, anticancer and antiinflammatory activities .
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Cat. No.: HY-N0290R
CAS No.: 4773-96-0
Mangiferin (Standard) is the analytical standard of Mangiferin. This product is intended for research and analytical applications. Mangiferin is a Nrf2 activator. Mangiferin suppresses nuclear translocation of the NF-κB subunits p65 and p50. Mangiferin exhibits antioxidant, antidiabetic, antihyperuricemic, antiviral, anticancer and antiinflammatory activities .
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Cat. No.: HY-P10030
CAS No.: 1801379-22-5
Target:  

Proteasome NF-κB

Research Areas:  

Inflammation/Immunology

DPLG3 is a specific chymotryptic-like β5i subunits inhibitor, with an IC50 of 4.5 nM. DPLG3 inhibits mouse i-20S with IC50 of 9.4 nM. DPLG3 downregulates the protein levels of NF-κB p50 and p65. DPLG3 can be used for immune disease research .
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Cat. No.: HY-183786
Research Areas:  

Cancer

Anticancer agent 327, a fluorescent Andrographolide (HY-N0191) derivative, is an NF-κB p50 inhibitor. Anticancer agent 327 covalently binds to the p50 subunit of NF-κB. Anticancer agent 327 reduces levels of multiple oncogenic p53 proteins via the autophagy/lysosome pathway. Anticancer agent 327 can be used for the research of pancreatic ductal adenocarcinoma (Ex/Em = 488/515 nm)[1].
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Cat. No.: HY-184324
CAS No.: 2975573-18-1
Anti-inflammatory agent 116 is an anti-inflammatory agent. Anti-inflammatory agent 116 inhibits the abnormal activation of the NF-κB/MAPK signaling pathway. Anti-inflammatory agent 116 binds to the p50 subunit and impairs the DNA-binding ability of the p65-p50 heterodimer. Anti-inflammatory agent 116 inhibits LPS-induced production of NO and MtROS, secretion of IL-1β and TNF-α, expression of iNOS and COX-2, phosphorylation of IKK, IκB, p65, p38, ERK and JNK, as well as nuclear translocation of p65. Anti-inflammatory agent 116 alleviates sepsis-associated acute liver injury in mice. Anti-inflammatory agent 116 can be used for the research of sepsis-associated acute liver injury .
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Cat. No.: HY-P810970
Synonyms: DCTN50, DCTN2, Dynactin subunit 2, 50 kDa dynein-associated polypeptide, Dynactin complex 50 kDa subunit, p50 dynamitin, DCTN-50

Host:  

Rabbit

Application:  

WB, IHC-P

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P71220
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: POLD2; Polymerase (DNA) Delta 2, Accessory subunit; DNA Polymerase Delta 2, Accessory subunit; Pol Delta B subunit (p50); DNA Polymerase Delta subunit p50; Polymerase (DNA Directed), Delta 2, Regulatory subunit (50kD); DNA Polymerase Delta subunit 2; Poly
Species:  
Source:  
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Cat. No.: HY-P85639
Synonyms: DKFZp686C01211; DNA binding factor KBF1; DNA binding factor KBF1 EBP1; DNA-binding factor KBF1; EBP 1; EBP-1; EBP1; KBF1; MGC54151; NF kappa B; NF kappaB; NF kappabeta; NF kB1; NFkappaB; NFKB 1; NFKB p105; NFKB p50; Nfkb1; NFKB1_HUMAN; Nuclear factor kappa B DNA binding subunit; Nuclear factor kappa-B, subunit 1; Nuclear factor NF kappa B p105 subunit; Nuclear factor NF kappa B p50 subunit; Nuclear factor NF-kappa-B p50 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B cells 1; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1; p105; p50; p84/NF-kappa-B1 p98.

Host:  

Mouse

Application:  

WB

Reactivity:  

Human

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Cat. No.: HY-P701136
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: DCTN2; p50 Dynamitin; Dynactin subunit 2; DCTN50; DCTN-50; Epididymis Secretory Sperm Binding Protein; RBp50; Epididymis Secretory Protein Li 77; 50 KDa Dynein-Associated Polypeptide; DYNAMITIN; Dynactin Complex 50 KDa subunit; HEL-S-77; Dynactin 2 (p50)
Species:  
Source:  
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Cat. No.: HY-N19791
CAS No.: 13410-15-6
6-Methoxymellein, a phytoalexin, is a NF-κB inhibitor. 6-Methoxymellein reduces nuclear localization and DNA binding activity of NF-κB p65 and p50 subunits. 6-Methoxymellein decreases mRNA transcription and secretion of IL-6 and IL-8. 6-Methoxymellein reduces the proportion of CD44 +/CD24 breast cancer cells, decreases expression of c-Myc, Sox-2 and Oct4, inhibits proliferation and migration of breast cancer cells, and reduces mammosphere growth. 6-Methoxymellein inhibits fungal growth of Trichophyton rubrum and Botrytis cinerea, and inhibits Trichophyton rubrum biofilm formation via hyphal disintegration. 6-Methoxymellein can be used for the research of breast cancer, tinea corporis, and carrot post-harvest storage rot .
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Cat. No.: HY-P81049
Synonyms: NFKB1; NF-KB; Nuclear factor NF-kappa-B p105 subunit; DNA-binding factor KBF1; EBP-1; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1; DNA-binding factor KBF1; EBP-1; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1; Nuclear factor NF-kappa-B p50 subunit; NFkB p105 / p50; NFkB p105/p50; nuclear factor kappa B subunit 1; NF-kB; CVID12; NF-kB1; NFKB-p50; NFkappaB; NF-kappaB; NFKB-p105; NF-kappa-B1; NF-kappabeta;

Host:  

Rabbit

Application:  

WB, IHC-P, IHC-F, FC, ICC/IF, ELISA

Reactivity:  

Human, Mouse

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Cat. No.: HY-P80244
Synonyms: DKFZp686C01211 antibody; DNA binding factor KBF1 antibody; DNA binding factor KBF1 EBP1 antibody; DNA-binding factor KBF1 antibody; EBP 1 antibody; EBP-1 antibody; EBP1 antibody; KBF1 antibody; MGC54151 antibody; NF kappa B antibody; NF kappaB antibody; NF kappabeta antibody; NF kB1 antibody; NFkappaB antibody; NFKB 1 antibody; NFKB p105 antibody; NFKB p50 antibody; Nfkb1 antibody; NFKB1_HUMAN antibody; Nuclear factor kappa B DNA binding subunit antibody; Nuclear factor kappa-B, subunit 1 antibody; Nuclear factor NF kappa B p105 subunit antibody; Nuclear factor NF kappa B p50 subunit antibody; Nuclear factor NF-kappa-B p50 subunit antibody; Nuclear factor of kappa light chain gene enhancer in B cells 1 antibody; Nuclear factor of kappa light polypeptide gene enhancer in B cells 1 antibody; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 antibody; p105 antibody; p50 antibody; p84/NF-kappa-B1 p98 antibody; Transcription factor NFKB1 antibody;

Host:  

Mouse

Application:  

WB, ICC/IF, IHC-P

Reactivity:  

Human, Mouse

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Cat. No.: HY-P71124
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NFKB1; KBF1; Nuclear Factor Kappa B subunit 1; P105; Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B-Cells 1; p50; Nuclear Factor NF-Kappa-B P105 subunit; Nuclear Factor Kappa-B DNA Binding subunit; DNA-Binding Factor KBF1; Nuclear Factor NF-
Species:  
Source:  
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Cat. No.: HY-P80960
Synonyms: CDC37A, CDC37, Hsp90 co-chaperone Cdc37, Hsp90 chaperone protein kinase-targeting subunit, p50Cdc37

Host:  

Rabbit

Application:  

WB, IHC-P, IP, FC

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P80961
Synonyms: CDC37A, CDC37, Hsp90 co-chaperone Cdc37, Hsp90 chaperone protein kinase-targeting subunit, p50Cdc37

Host:  

Rabbit

Application:  

WB, IP

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P80962
Synonyms: CDC37A, CDC37, Hsp90 co-chaperone Cdc37, Hsp90 chaperone protein kinase-targeting subunit, p50Cdc37

Host:  

Rabbit

Application:  

WB, IP

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P86580
Synonyms: CDC37; CDC37A; Hsp90 co-chaperone Cdc37; Hsp90 chaperone protein kinase-targeting subunit; p50Cdc37

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IP, ELISA

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P80962A
Synonyms: CDC37A, CDC37, Hsp90 co-chaperone Cdc37, Hsp90 chaperone protein kinase-targeting subunit, p50Cdc37

Host:  

Rabbit

Application:  

WB, IP

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P80764
Synonyms: NFKB1; Nuclear factor NF-kappa-B p105 subunit; DNA-binding factor KBF1; EBP-1; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1

Host:  

Mouse

Application:  

WB

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P86373
Synonyms: NFKB1; Nuclear factor NF-kappa-B p105 subunit; DNA-binding factor KBF1; EBP-1; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IP, ELISA

Reactivity:  

Human, Mouse, Rat

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