2 Results for "

p53 DUBTAC modulator-1

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "p53 DUBTAC modulator-1" in MCE Product Catalog:

Cat. No.: HY-180618
CAS No.: 3133073-71-6
Research Areas:  

Cancer

p53 DUBTAC modulator-1 (Compound A1) is a p53 Y220C DUBTAC modulator (Kd = 12.09 µM). p53 DUBTAC modulator-1 effectively reactivates and deubiquitinates mutant p53 Y220C. p53 DUBTAC modulator-1 upregulates p53 Y220C protein levels. p53 DUBTAC modulator-1 induces Apoptosis, reduces Bcl-2, inhibits Wnt signaling. p53 DUBTAC modulator-1 has anti-cancer activity against liver cancer .
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Cat. No.: HY-180619
CAS No.: 3133073-91-0
Target:  

DUBTACs MDM-2/p53

Research Areas:  

Cancer

p53 Y220C ligand-1(compound PK-A) is a target protein ligand of p53 DUBTAC modulator-1 (HY-180618). p53 Y220C ligand-1 exhibits potent activity in inhibiting cell proliferation in Huh7 cells .
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