p53 DUBTAC modulator-1
p53 DUBTAC modulator-1 (Compound A1) is a p53 Y220C DUBTAC modulator (Kd = 12.09 µM). p53 DUBTAC modulator-1 effectively reactivates and deubiquitinates mutant p53 Y220C. p53 DUBTAC modulator-1 upregulates p53 Y220C protein levels. p53 DUBTAC modulator-1 induces Apoptosis, reduces Bcl-2, inhibits Wnt signaling. p53 DUBTAC modulator-1 has anti-cancer activity against liver cancer.
For research use only. We do not sell to patients.
- Formula: C35H39N5O5
- Molecular Weight:609.71
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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Help & FAQs
Biological Activity
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Bcl-2 |
Chemical Information
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Molecular Weight 609.71
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Formula C35H39N5O5
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SMILES
C=CC(N1CCN(C(C1)=O)C2=CC=C(O2)CCC(N3CCN(CC3)CC4=CC(C#CCNC5=CC=CC=C5)=CC(C)=C4O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
p53 DUBTAC modulator-1 Related Classifications
HY-180618 Related Classifications
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