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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
169 Results for "
peptidyl
" in MedChemExpress (MCE) Product Catalog:
Products (169)
169 Results for "peptidyl" in MCE Product Catalog:
155
155 Publications Verification
Cat. No.: HY-18982
CAS No.: 22862-76-6
Synonyms: Flagecidin; Wuningmeisu C
54
54 Cited Publications
Cat. No.: HY-123606
CAS No.: 1652629-23-6
Target:
Research Areas:
GSK484 is a PAD4 inhibitor that effectively inhibits protein citrullination and the formation of neutrophil extracellular traps (NETs) by blocking the catalytic activity of PAD4. GSK484 suppresses the production of histone H3, MHC-I expression, CD8 + T cell activation, proliferation and inflammatory cytokine release. GSK484 reduces inflammation and bone destruction in collagen-induced rheumatoid arthritis, alleviates pain and mast cell activation in sickle cell disease, and improves myocardial ischemia-reperfusion injury and experimental colitis. In addition, GSK484 restores intestinal microbial homeostasis by reversing ferroptosis-induced dysbiosis. GSK484 can be used to study the disease mechanisms of rheumatoid arthritis, sickle cell disease, thrombosis, myocardial injury, colitis and other conditions .
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5
5 Cited Publications
Cat. No.: HY-K1054
MCE Blasticidin S, Sterile (10 mg/mL) is a filtered and sterilized antibiotic solution that can be used directly in cell culture. Blasticidin S is a peptidyl nucleoside antibiotic isolated from Streptomyces griseochromogenes. It acts by blocking hydrolysis of peptidyl-tRNA induced by release factors and inhibits peptide bond formation.
4
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Lefamulin (BC-3781) acetate is an orally active antibiotic. Lefamulin acetate inhibits protein synthesis by binding to the peptidyl transferase center of the 50S bacterial ribosome. Lefamulin acetate has anti-inflammatory activity. Lefamulin acetate can be used in the research of bacterial infections, such as bacterial pneumonia .
4
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Lefamulin (BC-3781) is an orally active antibiotic. Lefamulin inhibits protein synthesis by binding to the peptidyl transferase center of the 50S bacterial ribosome. Lefamulin has anti-inflammatory activity. Lefamulin can be used in the research of bacterial infections, such as bacterial pneumonia .
3
Sulfopin (PIN1-3) is a highly selective covalent inhibitor of Pin1 with an apparent Ki of 17 nM. Sulfopin blocks Myc-driven tumors in vivo. The peptidyl-prolyl isomerase, Pin1, is exploited in cancer to activate oncogenes and inactivate tumor suppressors .
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3
2
2 Cited Publications
Cat. No.: HY-P0190
CAS No.: 129203-60-7
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2
2 Cited Publications
Cat. No.: HY-B0027
CAS No.: 133868-46-9
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Valnemulin hydrochloride is an orally effective truncated pleurotin antibiotic that inhibits protein synthesis in bacteria by binding to peptidyl transferase in the 50s ribosome subunit. Valnemulin hydrochloride effectively eliminates Mycobacterium bovis in the lungs in an experimental bovine model of Mycoplasma bovis infection. Valnemulin hydrochloride can reduce the mortality of epidemic rabbit enteropathy and has no adverse effect on the growth performance of rabbits .
2
2 Cited Publications
Synonyms: M40403; GC4403
Imisopasem manganese (M40403) is a stable non-peptidyl mimetic of manganese superoxide MnSOD.
2
2 Cited Publications
Cat. No.: HY-P70007A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PPIA; Epididymis Secretory Sperm Binding Protein Li 69p; peptidylprolyl Isomerase A; peptidylprolyl Isomerase A (Cyclophilin A); CYPA; peptidyl-Prolyl Cis-Trans Isomerase; peptidyl-Prolyl Cis-Trans Isomerase A; T Cell Cyclophilin; Cyclosporin A-Binding Pr
2
2 Cited Publications
Cat. No.: HY-P7992
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ACE; Angiotensin I Converting Enzyme (peptidyl-Dipeptidase A) 1; Prev. DCP1; DCP; Angiotensin-Converting Enzyme; Dipeptidyl Carboxypeptidase 1; Dipeptidyl Carboxypeptidase I; Angiotensin Converting Enzyme; Kininase II; peptidyl-Dipeptidase A; CD143; Carbo
2
2
2 Cited Publications
Cat. No.: HY-P7441
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ACE2; Angiotensin I Converting Enzyme 2; Angiotensin Converting Enzyme 2; Angiotensin-Converting Enzyme 2; ACEH; ACE-Related Carboxypeptidase; Angiotensin I Converting Enzyme (peptidyl-Dipeptidase A) 2; Metalloprotease MPROT15; Angiotensin-Converting Enzy
1
1 Cited Publications
PIN1 inhibitor API-1 is a specific Pin1 (peptidyl-prolyl cis-trans isomerase NIMA-interacting 1) inhibitor (API-1) with an IC50 of 72.3 nM. PIN1 inhibitor API-1 directly and specifically binds to the Pin1 peptidyl-prolyl isomerase (PPIase) domain and potently inhibits Pin1 cis-trans isomerizing activity. PIN1 inhibitor API-1 retains the active conformation of pXPO5 and restores the ability of pXPO5 to transport pre-miRNAs from nucleus to cytoplasm, thus up-regulating the anticancer miRNA biogenesis to suppress both in vitro and in vivo hepatocellular carcinoma development .
1
1 Cited Publications
Cat. No.: HY-P1074
CAS No.: 203460-30-4
Target:
Research Areas:
1
1 Cited Publications
Cat. No.: HY-P71224
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PPID; PPIase D; peptidylprolyl Isomerase D; 40 KDa peptidyl-Prolyl Cis-Trans Isomerase D; CYP-40; peptidylprolyl Isomerase D (Cyclophilin D); peptidyl-Prolyl Cis-Trans Isomerase D; peptidyl-Prolyl Cis-Trans Isomerase; Rotamase D; Testicular Tissue Protein
1
1 Cited Publications
Cat. No.: HY-P70990
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PADI4; Protein-Arginine Deiminase Type IV; Prev. PADI5; HL-60 PAD; PDI5; PAD4; PDI4; peptidyl Arginine Deiminase Type IV; PAD; peptidylarginine Deiminase IV; peptidyl Arginine Deiminase, Type IV; PADI-H Protein; peptidyl Arginine Deiminase, Type V; PADI4
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
