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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
18 Results for "
phospho-Akt
" in MedChemExpress (MCE) Product Catalog:
Products (18)
18 Results for "phospho-Akt" in MCE Product Catalog:
4
4
4 Cited Publications
Cat. No.: HY-P80276
Synonyms: Akt 1 antibody; Akt antibody; Akt1 antibody; Akt1_HUMAN antibody; MGC99656 antibody; PKB antibody; PKB-ALPHA antibody; PRKBA antibody; Protein Kinase B Alpha antibody; Protein kinase B antibody; Proto-oncogene c-Akt antibody; RAC Alpha antibody; RAC antibody; RAC-alpha serine/threonine-protein kinase antibody; RAC-PK-alpha antibody;
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Cat. No.: HY-155580
CAS No.: 2927489-99-2
Target:
Research Areas:
MAO A/HSP90-IN-2 (compound 4-C) is a dual inhibitor of HSP90and MAO A with the IC50 values of 0.016 and 4.58 μM, respectively. MAO A/HSP90-IN-2 increases HSP70 expression and reduces HER2 and phospho-Akt expression, and decreases IFN-γ induced PD-L1 expression in GL26 cells. MAO A/HSP90-IN-2 inhibits the growth of Temozolomide (HY-17364) -sensitive and -resistant GBM cells, colon cancer, leukemia, non-small cell lung and other cancers, and has potential to inhibit tumor immune escape [1].
Cat. No.: HY-155577
CAS No.: 2927489-95-8
Target:
Research Areas:
MAO A/HSP90-IN-1 (4-b) is a MAO A/HSP90 dual inhibitor with IC50 value of 1.77 μM and 0.019 μM in Glioblastoma (GBM) GL26 cells and HSP90α, respectively. MAO A/HSP90-IN-1 (4-b) can inhibit MAO A activity, HSP90 binding and the expression of HER2 and phospho-Akt to inhibit the growth of GBM, they also reduce PD-L1 expression, which inhibits T cell activation. MAO A/HSP90-IN-1 (4-b) have potential to inhibit tumor immune escape. MAO A/HSP90-IN-1 (4-b) can be used for brain tumor-related diseases research .
Cat. No.: HY-B0606A
CAS No.: 59985-21-6
Synonyms: INS365 free base
Research Areas:
Diquafosol (INS365 free base) is a potent P2Y2 agonist. Diquafosol nhibits apoptosis and decreases ROS generation. Diquafosol has the potential for the research of dry eye .
(S)-PI3K-IN-2, an enantiomer of PI3K-IN-2 (HY-101517), is a ΡΙ3Κβ/δ inhibitor, with IC50s of 0.198 and 0.282 μΜ, respectively. (S)-PI3K-IN-2 can inhibit phospho AKT (ser473) in MDA-MB-468 cells (IC50=27 nM) .
Cat. No.: HY-P86450
Synonyms: Akt antibody; Akt1 antibody; Akt1 kinase antibody; Akt1m antibody; Akt2 antibody; Akt2 kinase antibody; Akt3 antibody; Akt3_HUMAN antibody; CAkt antibody; CWS6 antibody; DKFZp434N0250 antibody; HIHGHH antibody; kinase Akt1 antibody; MGC99656 antibody; MPPH antibody; Murine thymoma viral (v-Akt) homolog 2 antibody; pan-Akt antibody
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
