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photosensitiser

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-16045
    Hexaminolevulinate hydrochloride

    Hexyl 5-aminolevulinate hydrochloride; P-1206; 5-Aminolevulinic acid hexyl ester hydrochloride

    		 Fluorescent Dye Cancer
    Hexaminolevulinate (Hexyl 5-aminolevulinate) hydrochloride, a porphyrin precursor, is a photosensitiser that can be used in photodynamic therapy (PDT) for certain tumor. Hexaminolevulinate hydrochloride can improve the visualisation of bladder tumours .
    Hexaminolevulinate hydrochloride
  • HY-A0169AR
    Methyl aminolevulinate hydrochloride (Standard)

    		Reactive Oxygen Species (ROS) Reference Standards Photosensitizer Inflammation/Immunology Cancer
    Methyl aminolevulinate hydrochloride (Standard) is the analytical standard of Methyl aminolevulinate hydrochloride. This product is intended for research and analytical applications. Methyl aminolevulinate hydrochloride is a sensitizer used in photodynamic therapy (PDT). Methyl aminolevulinate hydrochloride penetrates the skin and induces the production of photoactive porphyrins including protoporphyrin IX in cells; upon exposure to appropriate light, it generates ROS, which triggers cellular oxidation and cell death. Methyl aminolevulinate hydrochloride acts as a photo-damage reversing agent through epidermal reconstruction, cytokine-mediated activation of dermal fibroblasts, elastin breakdown, new collagen formation, and compression of dilated capillaries. Methyl aminolevulinate hydrochloride reduces the expression of the proliferation marker Ki-67 and the early skin carcinogenesis marker TP53. Methyl aminolevulinate hydrochloride delays the onset of ultraviolet-induced skin tumors and reduces tumor burden in hairless mice. Methyl aminolevulinate hydrochloride is applicable to research related to actinic keratosis and basal cell carcinoma .
    Methyl aminolevulinate hydrochloride (Standard)

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