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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
53 Results for "
principal
" in MedChemExpress (MCE) Product Catalog:
Products (53)
53 Results for "principal" in MCE Product Catalog:
50
Target:
Áreas de investigación:
α-Amanitin is the principal toxin of several deadly poisonous mushrooms, exerting its toxic function by inhibiting RNA-polymerase II.
16
Category:
Infection Flavonoids Chalcones Humulus lupulus L. Phenols Polyphenols Plants Moraceae Disease Research Fields
Target:
4
4 Cited Publications
Synonyms: Disodium (R)-2-hydroxyglutarate
4
4 Cited Publications
Referencia número: HY-113038
No. CAS: 13095-47-1
Synonyms: (R)-2-Hydroxyglutarate; (R)-2-Hydroxyglutaric acid; (R)-2-Hydroxypentanedioic acid
1
1 Cited Publications
Synonyms: CP 526555
Target:
Áreas de investigación:
Varenicline (CP 526555) is an orally active partial agonist of α4β2 nicotinic acetylcholine receptor (α4β2 nAChR, IC50 = 250 nM), which is the principal mediator of nicotine dependence. Varenicline is also a partial agonist of α6β2 nAChR and a full agonist of α7β2 nAChR. Varenicline blocks the direct agonist effects of nicotine on nAChR while stimulates nAChR in a more moderate way, being widely used as an aid of smoking cessation .
1
Target:
1
1 Cited Publications
Synonyms: CP 526555-18
Varenicline (CP 526555) is an orally active partial agonist of α4β2 nicotinic acetylcholine receptor (α4β2 nAChR, IC50 = 250 nM), which is the principal mediator of nicotine dependence. Varenicline is also a partial agonist of α6β2 nAChR and a full agonist of α6β2 nAChR. Varenicline blocks the direct agonist effects of nicotine on nAChR while stimulates nAChR in a more moderate way, being widely used as an aid of smoking cessation .
1
1
1
1 Cited Publications
Referencia número: HY-N13015
No. CAS: 34199-21-8
Category:
Target:
1
Target:
Synonyms: N-Acetyl-L-carnosine
Áreas de investigación:
Synonyms: CP 526555 hydrochloride
Target:
Áreas de investigación:
Varenicline (CP 526555) is an orally active partial agonist of α4β2 nicotinic acetylcholine receptor (α4β2 nAChR, IC50 = 250 nM), which is the principal mediator of nicotine dependence. Varenicline is also a partial agonist of α6β2 nAChR and a full agonist of α6β2 nAChR. Varenicline blocks the direct agonist effects of nicotine on nAChR while stimulates nAChR in a more moderate way, being widely used as an aid of smoking cessation .
Referencia número: HY-W145520
No. CAS: 9037-22-3
Target:
Referencia número: HY-113046S
Pureza: ≥98.0%
Synonyms: 5-Methyl THF-13C5; 5-MTHF-13C,d5
Synonyms: CP 526555 dihydrochloride
Target:
Áreas de investigación:
Varenicline (CP 526555-18) is an orally active partial agonist of α4β2 nicotinic acetylcholine receptor (α4β2 nAChR, IC50 = 250 nM), which is the principal mediator of nicotine dependence. Varenicline is also a partial agonist of α6β2 nAChR and a full agonist of α7β2 nAChR. Varenicline blocks the direct agonist effects of nicotine on nAChR while stimulates nAChR in a more moderate way, being widely used as an aid of smoking cessation .
Target:
Áreas de investigación:
AST5902 trimesylate is the principal metabolite of Alflutinib (AST2818) both in vitro and in vivo. AST5902 trimesylate exerts antineoplastic activity. Alflutinib is an EGFR inhibitor .
Referencia número: HY-W654003
Synonyms: Disodium (R)-2-hydroxyglutarate-d5
Referencia número: HY-133848
No. CAS: 83130-01-2
Synonyms: OK-135
Target:
Áreas de investigación:
Alanycarb (OK-135) is a broad-spectrum oxime carbamate insecticide with contact and oral toxicity. Alanycarb is effective against a wide variety of insect pests and is a pro-insecticide. The principal active molecule produced by the biological modification of Alanycarb within target organisms is methomyl .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
