1. JAK/STAT Signaling
    Protein Tyrosine Kinase/RTK
    Metabolic Enzyme/Protease
  2. EGFR
    Drug Metabolite
  3. AST5902 trimesylate

AST5902 trimesylate 

Cat. No.: HY-138627A
Handling Instructions

AST5902 trimesylate is the principal metabolite of Alflutinib (AST2818) both in vitro and in vivo. AST5902 trimesylate exerts antineoplastic activity. Alflutinib is an EGFR inhibitor.

For research use only. We do not sell to patients.

AST5902 trimesylate Chemical Structure

AST5902 trimesylate Chemical Structure

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 445 In-stock
Estimated Time of Arrival: December 31
5 mg USD 300 In-stock
Estimated Time of Arrival: December 31
10 mg USD 480 In-stock
Estimated Time of Arrival: December 31
25 mg USD 950 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1450 In-stock
Estimated Time of Arrival: December 31
100 mg USD 2250 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

AST5902 trimesylate is the principal metabolite of Alflutinib (AST2818) both in vitro and in vivo. AST5902 trimesylate exerts antineoplastic activity. Alflutinib is an EGFR inhibitor[1].

IC50 & Target

EGFR[1]

Molecular Weight

842.88

Formula

C₃₀H₄₁F₃N₈O₁₁S₃

SMILES

CS(=O)(O)=O.C=CC(NC1=CC(NC2=NC=CC(C3=CN(C)C4=C3C=CC=C4)=N2)=C(OCC(F)(F)F)N=C1N(C)CCNC)=O.CS(=O)(O)=O.CS(=O)(O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

References
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Keywords:

AST5902 trimesylateEGFRDrug MetaboliteEpidermal growth factor receptorErbB-1HER1Alflutinibmetabolite antineoplasticpharmacokineticsInhibitorinhibitorinhibit

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Product Name:
AST5902 trimesylate
Cat. No.:
HY-138627A
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