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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
132 Results for "
proliferator-activated
" in MedChemExpress (MCE) Product Catalog:
Products (132)
132 Results for "proliferator-activated" in MCE Product Catalog:
83
83 Publications Verification
GW6471 is a selective peroxisome proliferator-activated receptor α (PPARα) antagonist. GW6471 reduces cancer stem cell viability, proliferation, and spheroid formation. GW6471 induces apoptosis and causes metabolic impairment including energy imbalance. GW6471 can be used for the research of paragangliomas and triple-negative breast cancer .
51
51 Cited Publications
Cat. No.: HY-17538
CAS No.: 49671-76-3
Research Areas:
ZLN005 is a potent activator of peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) .
50
Target:
Research Areas:
Pioglitazone (U 72107) is an orally active and selective PPARγ (peroxisome proliferator-activated receptor) agonist with high affinity binding to the PPARγ ligand-binding domain with EC50 of 0.93 and 0.99 μM for human and mouse PPARγ, respectively. Pioglitazone can be used in diabetes research .
17
12
12 Cited Publications
Target:
Research Areas:
GW 1929 is an orally active peroxisome proliferator-activated receptor-γ (PPARγ) agonist with a pKi of 8.84 for human PPAR-γ, and pEC50s of 8.56 and 8.27 for human PPAR-γ and murine PPAR-γ, respectively. GW 1929 (hydrochloride) has antidiabetic efficacy and neuroprotective potential .
10
10 Cited Publications
Cat. No.: HY-19937
CAS No.: 495399-09-2
Target:
Research Areas:
Saroglitazar is a novel peroxisome proliferator-activated receptor (PPAR) agonist with predominant PPARα and moderate PPARγ activity with EC50 values of 0.65 pM and 3 nM in HepG2 cells, respectively.
10
10 Cited Publications
Cat. No.: HY-N0234
CAS No.: 19879-30-2
Synonyms: 7-O-Methylbavachin; Bavachinin A
Category:
Flavonoids Monophenols Leguminosae Flavonones Phenols Psoralea corylifolia L. Plants Disease Research Fields Inflammation/Immunology
Target:
10
10 Cited Publications
Cat. No.: HY-19937A
CAS No.: 1639792-20-3
Target:
Research Areas:
Saroglitazar magnesium is a novel peroxisome proliferator-activated receptor (PPAR) agonist with predominant PPARα and moderate PPARγ activity with EC50 values of 0.65 pM and 3 nM in HepG2 cells, respectively.
8
8 Cited Publications
Cat. No.: HY-P7999
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PPARG; PPARG5; Peroxisome proliferator activated Receptor Gamma; Peroxisome proliferator-activated Receptor-Gamma Splicing; NR1C3; Peroxisome Proliferative activated Receptor, Gamma; Peroxisome proliferator-activated Receptor Gamma; Peroxisome Proliferato
5
5 Cited Publications
Cat. No.: HY-N0246
CAS No.: 20736-09-8
5
5 Cited Publications
Cat. No.: HY-N1472
CAS No.: 88182-33-6
2
2 Cited Publications
Cat. No.: HY-P7996
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PPARA; HPPAR; Prev. PPAR; PPAR-Alpha; Peroxisome proliferator-activated Receptor Alpha; Alternative Protein PPARA; NR1C1; PPARalpha; Nuclear Receptor Subfamily 1 Group C Member 1; Peroxisome proliferator activated Receptor Alpha; Peroxisome Proliferative
2
2 Cited Publications
Cat. No.: HY-P7507
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ANGPTL4; Peroxisome proliferator-activated Receptor (PPAR) Gamma Induced Angiopoietin-Related Protein; Angiopoietin Like 4; Hepatic Angiopoietin-Related Protein; HFARP; PPARG Angiopoietin Related Protein; PGAR; Fasting-Induced Adipose Factor; ARP4; Angiop
2
1
1
1 Cited Publications
Target:
Research Areas:
CUDA is a potent inhibitor of soluble epoxide hydrolase (sEH), with IC50s of 11.1 nM and 112 nM for mouse sEH and human sEH, respectively . CUDA selectively increases peroxisome proliferator-activated receptor (PPAR) alpha activity. CUDA may be valuable for the research of cardiovascular disease .
1
Target:
Research Areas:
Arhalofenate (MBX 102) is a selective partial agonist of peroxisome proliferator-activated receptor (PPAR)-γ, used for the treatment of type 2 diabetes.
1
1 Cited Publications
Cat. No.: HY-121538A
Target:
Research Areas:
CUDA disodium is a potent inhibitor of soluble epoxide hydrolase (sEH), with IC50s of 11.1 nM and 112 nM for mouse sEH and human sEH, respectively . CUDA disodium selectively increases peroxisome proliferator-activated receptor (PPAR) alpha activity. CUDA disodium may be valuable for the research of cardiovascular disease .
1
1
1 Cited Publications
Cat. No.: HY-P702843
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PPARA; HPPAR; Prev. PPAR; PPAR-Alpha; Peroxisome proliferator-activated Receptor Alpha; Alternative Protein PPARA; NR1C1; PPARalpha; Nuclear Receptor Subfamily 1 Group C Member 1; Peroxisome proliferator activated Receptor Alpha; Peroxisome Proliferative
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
