2 Results for "

promyostatin

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "promyostatin" in MCE Product Catalog:

Cat. No.: HY-P99441
CAS No.: 2278276-46-1
Synonyms: SRK-015

Target:  

TGF-beta/Smad

Research Areas:  

Neurological Disease

Apitegromab (SRK-015) is an anti-promyostatin monoclonal antibody. Apitegromab can be used for the research of neuromuscular disease including spinal muscular atrophy .
loading...
    loading...
Cat. No.: HY-P990993
CAS No.: 2922218-19-5
Synonyms: GYM-329, RG6237, RG-70240

Target:  

TGF-beta/Smad

Research Areas:  

Inflammation/Immunology

Emugrobart (GYM-329, RG6237, RG-70240) is a humanized IgG1κ antibody targeting myostatin (Myostatin; GDF8). Emugrobart binds to pro-myostatin and latent myostatin, blocking their cleavage into mature myostatin; it also has a clearance function, which transports bound myostatin for degradation and allows for cyclic reuse. Emugrobart enhances muscle strength in mouse models of muscle atrophy and increases muscle mass in cynomolgus monkeys. Emugrobart can be used in research on spinal muscular atrophy and facioscapulohumeral muscular dystrophy .
loading...
    loading...