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Results for "

reactive reagent

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Reactive Oxygen Species (ROS) (1) ADC Linker (10) Biochemical Assay Reagents (44) Drug Intermediate (2) E3 Ligase Ligand-Linker Conjugates (1) Endogenous Metabolite (1) Environmental Pollutants (1) Exosomes (1) Fluorescent Dye (34) Herbicide (1) Liposome (10) MOFs (1) N-myristoyltransferase (1) Reference Standards (2) TRP Channel (1)
By Research Areas:	Cancer (5) Infection (2) Inflammation/Immunology (6) Metabolic Disease (2) Neurological Disease (1)
Click Chemistry:	Labeling and Fluorescence Imaging (4) DBCO (4) PROTAC Synthesis (1) Azide (6) BCN (1) Tetrazine (4) Alkynes (4)
Oligonucleotides:	Pegylated Lipids (9) Phospholipids (1)

104

Inhibitors & Agonists

Fluorescent Dyes

Biochemical Assay Reagents

Natural
Products

Click Chemistry

Oligonucleotides

GMP Molecules

Targets Recommended: Reactive Oxygen Species (ROS)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-D0819

CY5-SE Maximum Cited Publications 37 Publications Verification Cy5 NHS Ester; Sulfo-Cyanine5 Succinimidyl Ester	Fluorescent Dye	Others
Cy5-SE (Cy5 NHS Ester) is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. This dye requires small amount of organic co-solvent (such as DMF or DMSO) to be used in labeling reaction. This reagent is ideal for very cost-efficient labeling of soluble proteins, as well as all kinds of peptides and oligonucleotides. This reagent also works well in organic solvents for small molecule labeling. Excitation (nm):649, Emission (nm): 670.

HY-D0802

Biotin NHS 15+ Cited Publications Biotin N-hydroxysuccinimide ester; NHS-Biotin	Fluorescent Dye	Others
Biotin NHS is an amino reactive biotin reagent used in the preparation of biotinylated surfaces or polypeptides.

HY-111496

Sulfo-NHS-SS-Biotin sodium 4 Publications Verification	Biochemical Assay Reagents	Others
Sulfo-NHS-SS-biotin sodium is a long-chain cleavable and cell-impermeant amine-reactive biotinylation reagent. Sulfo-NHS-SS-biotin sodium can be used for the labeling and purifying of cell-surface protein .

HY-W441011

DSPE-NHS	Liposome	Neurological Disease Inflammation/Immunology Cancer
DSPE-NHS is a bioconjugation phospholipid molecule with two hydrophobic lipid tails. DSPE-NHS is a self-assembling reagent which forms lipid bilayer in aqueous solution. The NHS-ester is reactive with N-terminal of protein/peptide or other amine molecule to form a stable amide linkage. DSPE-NHS labels antibodies. DSPE-NHS can be used to prepare liposomes as agent nanocarrier .

HY-79880

N,N'-Carbonyldiimidazole 1,1'-Carbonyldiimidazole	MOFs	Others
N,N'-Carbonyldiimidazole (1,1'-Carbonyldiimidazole) is a highly reactive carboxylating reagent that can activate hydroxyl groups to form reactive carbonyl groups. N,N'-Carbonyldiimidazole can be used as a coupling agent and a peptide synthesis reagent .

HY-Y0481

Tin(II) chloride, 98% Stannous chloride, 98%; Tin(II) chloride, anhydrous, 98%; Anhydrous stannous chloride, 98%	Biochemical Assay Reagents	Others
Anhydrous stannous chloride, 98% is a biochemical reagent with genotoxicity, mutagenicity, mitotic recombinogenicity, and reactive oxygen species-inducing activity.

HY-136205

IA-Alkyne 4 Publications Verification Iodoacetamide-alkyne; N-Hex-5-ynyl-2-iodo-acetamide	TRP Channel	Infection Inflammation/Immunology
IA-Alkyne (Iodoacetamide-alkyne; N-Hex-5-ynyl-2-iodo-acetamide) is a TRP channel (TRPC) agonist and has the potential for the study of respiratory infection . IA-Alkyne can be used to develop an isotopically tagged probe for quantitative *cysteine-reactivity* profiling . IA-Alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-100215

Biotin Hydrazide 2 Publications Verification	Biochemical Assay Reagents	Others
Biotin Hydrazide is a carbonyl-reactive biotinylation reagent, which is a carbonyl probe.

HY-D0913

1-Methyl-7-nitroisatoic anhydride 3 Publications Verification 1M7	Fluorescent Dye	Others
1-Methyl-7-nitroisatoic anhydride (1M7) is a reagent that detects local nucleotide flexibility, for probing 2'-hydroxyl reactivity, can be used for RNA structure analysis .

HY-W879045

Endo-BCN-PEG5-amine Endo-BCN-PEG5-NH2	Biochemical Assay Reagents	Others
Endo-BCN-PEG5-amine (Endo-BCN-PEG5-NH2) is a click chemistry crosslinker reagent. The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc .

HY-76222

Isatoic anhydride	Drug Intermediate	Others
Isatoic anhydride is a single-adduct forming reagent and a monofunctional SHAPE reagent. Isatoic anhydride reacts with the 2'-hydroxyl group of RNA nucleotides via a single reactive group to form a single adduct, without forming cross-links between nucleotides. In SHAPE-JuMP experiments, Isatoic anhydride serves as a control reagent for single-adduct formation, which is used to distinguish true cross-links from single-adduct formation .

HY-136426

Trifludimoxazin	Environmental Pollutants Reactive Oxygen Species (ROS) Herbicide	Others
Trifludimoxazin is a click chemistry reagent, a protoporphyrinogen oxidase (PPO) inhibitor and herbicide. Trifludimoxazin inhibits PPO, accumulates reactive oxygen species, damages cell membranes, and thereby causes weed death. Trifludimoxazin exhibits high-efficiency activity in controlling broadleaf weeds and grassy weeds .

HY-W998680

Fluorescein-maleimide 5-FITC-Maleimide	Fluorescent Dye	Others
Fluorescein-maleimide (5-FITC-Maleimide) is a thiol-reactive fluorescent derivatization reagent and non-specific protein labeling reagent. Fluorescein-maleimide covalently binds to protein thiol groups for protein labeling. Fluorescein-maleimide covalently binds to protein amino and imidazole groups under neutral pH conditions. Fluorescein-maleimide is used for fluorescent labeling of proteins, nucleic acids or other molecules containing one or more thiol groups (Ex/Em = 494/519 nm) .

HY-D1635

Sulfo-NHS-LC-LC-Biotin Biotin-XX-SSE	Fluorescent Dye Exosomes	Infection
Sulfo-NHS-LC-LC-Biotin (Biotin-XX-SSE), a biotin reagent, is used to label the proteins exposed to the external leaflet of intact exosomes and contains a larger spacer arm between the biotin and amine reactive linker. The size of this linker helps to overcome steric hindrance and increases labeling efficiency at the crowded exosome surface .

HY-137541

2-Nitro-5-thiocyanatobenzoic acid NTCB	Biochemical Assay Reagents	Others
2-Nitro-5-thiocyanatobenzoic acid (NTCB) is a highly reactive reagent that transfers its cyano group rapidly to a nucleophilic thiolate. 2-Nitro-5-thiocyanatobenzoic acid has been proposed as a reagent for converting thiol groups in proteins into their S-cyano derivatives .

HY-151776

Cy3 methyltetrazine TZ-Cy3	Fluorescent Dye	Others
Cy3 methyltetrazine (TZ-Cy3) is a click chemistry reagent with methyltetrazine building blocks that is highly reactive towards cyclooctene. Cy3 methyltetrazine is also a tetrazine-modified fluorescent probe that can be used to analyze protein phosphorylation in solution and living cells .

HY-D0820

CY5-YNE Sulfo-Cyanine5-alkyne	Fluorescent Dye	Others
CY5-YNE (Sulfo-Cyanine5-alkyne) is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides (Ex: 650 nM; Em: 680 nm). CY5-YNE is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-DY1063

CY5-SE (solution)	Fluorescent Dye	Others
Cy5-SE (Cy5 NHS Ester) (solution) is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. This dye requires small amount of organic co-solvent (such as DMF or DMSO) to be used in labeling reaction. This reagent is ideal for very cost-efficient labeling of soluble proteins, as well as all kinds of peptides and oligonucleotides. This reagent also works well in organic solvents for small molecule labeling. Excitation (nm) :649, Emission (nm) : 670. Solvent and concentration: DMSO: 10 mM

HY-151771

DACN(Tos,Mal)	ADC Linker	Others
DACN(Tos,Mal) is a click chemistry reagent containing an azide. DACN(Tos,Mal) possess high thermal and chemical stability along with comparable click reactivity .

HY-D2575

WYneN	Biochemical Assay Reagents	Inflammation/Immunology
WYneN (compound 10) is a functionalized Wittig-alkyne probe. WYneN exhibits strong reactivity with sulfinic acid dipeptide models, similar to the parent Wittig reagent. WYneN can be used to reveal the function of oxidative modifications on a proteome-wide scale .

HY-D0878

TAPSO	Biochemical Assay Reagents	Others
TAPSO is a commonly used biological buffer and pH-stabilizing reagent, with an effective pH range of 7-8 and a pKa range of 7.5-9. TAPSO contains a Tris group, exhibits considerable reactivity, and can interact with zwitterionic glycine peptides .

HY-W800839

TCO-PEG4-TFP ester	Biochemical Assay Reagents	Others
TCO-PEG4-TFP Ester is an amine-reactive labeling reagent used to modify proteins, antibodies, and other amine-containing biopolymers. A 2,3,5,6-tetrafluorophenol (TFP) is a reactive ester that displays much better stability toward hydrolysis in aqueous media resulting in more efficiency and better reproducible labeling of biopolymers. TFP ester of carboxylic acids react with primary amines at the same rate as NHS ester forming covalent amide bond that is identical to one formed by the reaction between primary amines and NHS esters or sulfo-NHS esters.

HY-21626

4-Tolylboronic acid p-Tolylboronic acid	Biochemical Assay Reagents	Others
4-Tolylboronic acid is an organoboron compound with important chemical applications. It can be used as an important intermediate in organic synthesis for the synthesis of organic compounds such as drugs, pesticides, and cosmetics, as well as for the research of coordination chemistry and material science. Due to its high chemical reactivity, 4-Tolylboronic acid has become a widely used reagent in organic synthesis.

HY-D2529

Cy5-PEG2000-SH	Fluorescent Dye	Others
Cy5-PEG2000-SH is a fluorescent labeling reagent that combines Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.

HY-W051391

1,4,7-Trimethyl-1,4,7-triazonane Me3TACN	Biochemical Assay Reagents	Others
1,4,7-Trimethyl-1,4,7-triazonane, also known as TMT or trimethylenetris(aziridine), is a cyclic organic compound. TMT is commonly used as a crosslinking agent and a precursor for polymer and resin synthesis. In addition, it is used as a stabilizer in the production of polyurethane foam and as a curing agent for epoxy resins. Due to its high reactivity and stability, TMT is considered to be a versatile and efficient reagent in various applications.

HY-176509A

DSPE-PEG2000-CHO	Liposome	Others
DSPE-PEG2000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG2000-CHO can be used for drug delivery .

HY-E70394

S-Acetonyl-CoA Acetonyl-coenzyme A	Biochemical Assay Reagents N-myristoyltransferase	Metabolic Disease
S-Acetonyl-CoA (Acetonyl-coenzyme A) is a non-reactive structural analog of acetyl-CoA that acts as a competitive inhibitor against multiple target enzymes. S-Acetonyl-CoA lacks the characteristic thioester group of acetyl-CoA, retaining only a thioether structure. S-Acetonyl-CoA competes with acetyl-CoA for binding to citrate synthase, phosphate transacetylase, carnitine acetyltransferase, and N-myristoyltransferase 1. S-Acetonyl-CoA serves as a reagent for investigating acetyl-CoA-dependent physiological processes .

HY-151794

DACN(Ms) hydrochloride	ADC Linker	Others
DACN(Ms) hydrochloride (compound 1ba) is a click chemistry reagent containing cyclononyne alkyne. DCN(Ms) hydrochloride has high thermal stability, chemical stability, water solubility, and high reactivity for cycloaddition reactions .

HY-151795

DACN(Tos) hydrochloride	ADC Linker	Others
DACN(Tos) hydrochloride is a click chemistry reagent containing a cycloalkyne group. The alkyne moiety within the ring has a unique bent structure and high reactivity toward cycloaddition reactions, such strain-promoted azide-alkyne cycloadditions (SPAAC) by using cycloalkynes. DACNs possesses high thermal and chemical stability along with comparable click reactivity. DACN(Tos) hydrochloride can be used for the research of molecular conjugation .

HY-125501

Biotin-XX hydrazide Biotin-(AC5)2-hydrazide	Biochemical Assay Reagents	Others
Biotin-XX hydrazide (Biotin-(AC5)2-hydrazide) is a carbonyl-reactive biotinylation reagent which contains two aminohexanoic acid spacers. Biotin-XX hydrazide has higher efficiency of avidin-binding .

HY-W440927

Stearic acid-PEG2000-NHS	Liposome	Others
Stearic acid-PEG2000-NHS is an amphiphatic PEG polymer which forms micelles in an aqueous solution for drug-loaded nanoparticles. The NHS ester is reactive with amine to form a stable amide bond. Reagent grade, for research purpose.

HY-D1352A

Sulfo-Cyanine7 NHS ester TEA	Fluorescent Dye	Others
Sulfo-Cyanine7 NHS ester (TEA) is an amine-reactive succinimide ester. Sulfo-Cyanine7 NHS ester (TEA) reagent allows to prepare sulfo-Cyanine7-labeled biomolecules, such as proteins, with ease. Dye labeled molecules can be subsequently used for various research and agent design related experiments.

HY-151712

Sulfo-Cy5-Methyltetrazine	Fluorescent Dye	Others
Sulfo-Cy5-Methyltetrazine is a click chemistry reagent containing a methyltetrazine group. Sulfo-Cy5-Methyltetrazine acts as a fluorophore linker for trans-cyclooctene-based labeling. Sulfo-Cy5-Methyltetrazine shows good stability at physiological pH and is also highly reactive towards cyclooctene.

HY-D2531

Cy5-PEG5000-SH	Fluorescent Dye	Others
Cy5-PEG5000-SH is a fluorescent labeling reagent that combines Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.

HY-151713

Sulfo-Cy3-Methyltetrazine	Fluorescent Dye	Others
Sulfo-Cy3-Methyltetrazine (figure 7 compound 5) is a click chemistry reagent containing methyltetrazine and a water-soluble dye. Sulfo-Cy3-Methyltetrazine shows good stability at physiological pH. Sulfo-Cy3-Methyltetrazine can be coupled to trans-cyclooctene and is also highly reactive towards cyclooctene .

HY-D2556

Cy5.5-PEG1000-SH	Fluorescent Dye	Others
Cy5.5-PEG1000-SH is a fluorescent labeling reagent that combines Cy5.5 (HY-D0924) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.

HY-151697

DACN(Tos2)	ADC Linker	Others
DACN(Tos2) is a a click chemistry reagent containing an cycloalkynes group. The alkyne moiety within the ring has a unique bent structure and high reactivity toward cycloaddition reactions. DACN(Tos2) through such strain-promoted azide-alkyne cycloadditions (SPAAC) using cycloalkynes. DACN(Tos2) can be used for the research of molecular conjugation .

HY-W612372

4-(Bromomethyl)benzenesulfonyl fluoride Fluorosulfonylbenzyl bromide	Biochemical Assay Reagents Endogenous Metabolite
4-(Bromomethyl)benzenesulfonyl fluoride (Fluorosulfonylbenzyl bromide) is an important chemical reagent with good biological activity. 4-(Bromomethyl)benzenesulfonyl fluoride can be used to prepare various bioactive molecules, especially in the process of compound discovery and synthesis, showing excellent reactivity. 4-(Bromomethyl)benzenesulfonyl fluoride is often used in the development of new biological agents, promoting the research progress of organic chemistry and biochemistry.

HY-176509C

DSPE-PEG5000-CHO	Liposome	Others
DSPE-PEG5000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG5000-CHO can be used for drug delivery .

HY-157006A

TCO-PEG3-NH2	Biochemical Assay Reagents	Others
TCO-PEG3-NH2 is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups. The amino group of TCO-PEG3-NH2 can react with compounds containing carboxyl, ester, or other reactive groups to form stable amide bonds, enabling site-specific conjugation or modification of biomolecules.

HY-176509

DSPE-PEG1000-CHO	Liposome	Others
DSPE-PEG1000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG1000-CHO can be used for drug delivery .

HY-D1886

Vari Fluor 647 SE	Fluorescent Dye	Others
Vari Fluor 647 SE is a fluorescent dye, SE stands for "succinimidyl ester". Vari Fluor 647 SE belongs to the Vari Fluor family of labeling reagents used in cell and molecular biology research. Vari Fluor 647 SE can react with an amino group to form a covalent bond, thereby introducing Vari Fluor 647 dye into the target molecule or cell. Vari Fluor 647 SE is a reactive dye that produces a fluorescent signal after binding to a target molecule or cell.

HY-W190918

endo-BCN-PEG4-amine	Biochemical Assay Reagents	Others
endo-BCN-PEG4-amine is a click chemistry crosslinker reagent. The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.

HY-79880R

N,N'-Carbonyldiimidazole (Standard) 1,1'-Carbonyldiimidazole (Standard)	Biochemical Assay Reagents Reference Standards	Others
N,N'-Carbonyldiimidazole (Standard) (1,1'-Carbonyldiimidazole (Standard)) is the analytical standard of N,N'-Carbonyldiimidazole (HY-79880). This product is intended for research and analytical applications. N,N'-Carbonyldiimidazole (1,1'-Carbonyldiimidazole) is a highly reactive carboxylating reagent that can activate hydroxyl groups to form reactive carbonyl groups. N,N'-Carbonyldiimidazole can be used as a coupling agent and a peptide synthesis reagent .

HY-W879025

Endo-BCN-PEG8-amine Endo-BCN-PEG8-NH2	Biochemical Assay Reagents	Others
Endo-BCN-PEG8-amine (Endo-BCN-PEG8-NH2) is a click chemistry crosslinker reagent. The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc .

HY-151766

DACN(Tos,Suc-OH)	ADC Linker	Others
DACN(Tos,Suc-OH) is a click chemistry reagent containing a cycloalkyne group. The alkyne moiety within the ring has a unique bent structure and high reactivity toward cycloaddition reactions. Such strain-promoted azide-alkyne cycloadditions (SPAAC) using cycloalkynes have served for reliable molecular conjugation in a broad range of fields. The nitrogens are used as connection points for a variety of functional units. DACNs possess high thermal and chemical stability along with comparable click reactivity .

HY-173569

DBCO-propargyl-PEG5-TFP ester	Biochemical Assay Reagents	Others
DBCO-propargyl-PEG5-TFP ester is an amine-reactive labeling reagent. DBCO-propargyl-PEG5-TFP ester contains a DBCO group, which can undergo a strain-promoted alkyne-azide cycloaddition (SPAAC) reaction with molecules containing an azide group ^{[1] ^.}

HY-W451405

2,5-Dioxopyrrolidin-1-yl hept-6-ynoate	Biochemical Assay Reagents	Others
2,5-Dioxopyrrolidin-1-yl hept-6-ynoate is an amine reactive four carbon reagent that can be used for derivatizing peptides, antibodies, amine coated surfaces etc. The alkyne group reacts with azide-bearing compounds or biomolecules in copper catalyzed Click Chemistry reactions.

HY-D2532

Cy5-PEG10000-SH	Fluorescent Dye	Others
Cy5-PEG10000-SH is a fluorescent labeling reagent that combines Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.

HY-D2589

Cy7.5 PEG-SH	Fluorescent Dye	Others
Cy7.5 PEG-SH is a fluorescent labeling reagent that combines CY7.5 (HY-D0926) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em = 770/820 nm).

Cat. No.	Product Name	Type

HY-D0819

CY5-SE

Maximum Cited Publications

37 Publications Verification

Cy5 NHS Ester; Sulfo-Cyanine5 Succinimidyl Ester

Fluorescent Dyes

Cy5-SE (Cy5 NHS Ester) is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. This dye requires small amount of organic co-solvent (such as DMF or DMSO) to be used in labeling reaction. This reagent is ideal for very cost-efficient labeling of soluble proteins, as well as all kinds of peptides and oligonucleotides. This reagent also works well in organic solvents for small molecule labeling. Excitation (nm):649, Emission (nm): 670.

HY-D0802

Biotin NHS 15+ Cited Publications Biotin N-hydroxysuccinimide ester; NHS-Biotin	Fluorescent Dyes
Biotin NHS is an amino reactive biotin reagent used in the preparation of biotinylated surfaces or polypeptides.

HY-111496

Sulfo-NHS-SS-Biotin sodium 4 Publications Verification	Fluorescent Dyes
Sulfo-NHS-SS-biotin sodium is a long-chain cleavable and cell-impermeant amine-reactive biotinylation reagent. Sulfo-NHS-SS-biotin sodium can be used for the labeling and purifying of cell-surface protein .

HY-D0913

1-Methyl-7-nitroisatoic anhydride 3 Publications Verification 1M7	Fluorescent Dyes
1-Methyl-7-nitroisatoic anhydride (1M7) is a reagent that detects local nucleotide flexibility, for probing 2'-hydroxyl reactivity, can be used for RNA structure analysis .

HY-W998680

Fluorescein-maleimide

5-FITC-Maleimide

Fluorescent Dyes

Fluorescein-maleimide (5-FITC-Maleimide) is a thiol-reactive fluorescent derivatization reagent and non-specific protein labeling reagent. Fluorescein-maleimide covalently binds to protein thiol groups for protein labeling. Fluorescein-maleimide covalently binds to protein amino and imidazole groups under neutral pH conditions. Fluorescein-maleimide is used for fluorescent labeling of proteins, nucleic acids or other molecules containing one or more thiol groups (Ex/Em = 494/519 nm) .

HY-114354

BODIPY FL alkyne

BOD FL alkyne

Fluorescent Dyes

BODIPY (BOD) FL alkyne is an alkyne-containing BODIPY fluorophore derivative. BODIPY FL alkyne is a bioorthogonal labeling reagent with low toxicity and extremely low non-specific reactivity, and it is widely used in fluorescent bioimaging. BODIPY FL alkyne specifically labels azide groups on intracellular glycoconjugates mainly via strain-promoted azide-alkyne cycloaddition (SPAAC), or mediates site-specific conjugation with proteins such as IL-33, and supports positive cross-linking with other probes (e.g., DBCO-SCy5) for dual labeling. With the advantages of high specificity and low background interference, BODIPY FL alkyne can be used in the research of related diseases such as asthma, atopic dermatitis and inflammatory bowel disease .

HY-151776

Cy3 methyltetrazine TZ-Cy3	Fluorescent Dyes
Cy3 methyltetrazine (TZ-Cy3) is a click chemistry reagent with methyltetrazine building blocks that is highly reactive towards cyclooctene. Cy3 methyltetrazine is also a tetrazine-modified fluorescent probe that can be used to analyze protein phosphorylation in solution and living cells .

HY-D0820

CY5-YNE Sulfo-Cyanine5-alkyne	Fluorescent Dyes
CY5-YNE (Sulfo-Cyanine5-alkyne) is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides (Ex: 650 nM; Em: 680 nm). CY5-YNE is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-DY1063

CY5-SE (solution)

Fluorescent Dyes

Cy5-SE (Cy5 NHS Ester) (solution) is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. This dye requires small amount of organic co-solvent (such as DMF or DMSO) to be used in labeling reaction. This reagent is ideal for very cost-efficient labeling of soluble proteins, as well as all kinds of peptides and oligonucleotides. This reagent also works well in organic solvents for small molecule labeling. Excitation (nm) :649, Emission (nm) : 670.
Solvent and concentration: DMSO: 10 mM

HY-D2575

WYneN	Fluorescent Dyes
WYneN (compound 10) is a functionalized Wittig-alkyne probe. WYneN exhibits strong reactivity with sulfinic acid dipeptide models, similar to the parent Wittig reagent. WYneN can be used to reveal the function of oxidative modifications on a proteome-wide scale .

HY-D2529

Cy5-PEG2000-SH	Fluorescent Dyes
Cy5-PEG2000-SH is a fluorescent labeling reagent that combines Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.

HY-D1352A

Sulfo-Cyanine7 NHS ester TEA	Fluorescent Dyes
Sulfo-Cyanine7 NHS ester (TEA) is an amine-reactive succinimide ester. Sulfo-Cyanine7 NHS ester (TEA) reagent allows to prepare sulfo-Cyanine7-labeled biomolecules, such as proteins, with ease. Dye labeled molecules can be subsequently used for various research and agent design related experiments.

HY-151712

Sulfo-Cy5-Methyltetrazine	Fluorescent Dyes
Sulfo-Cy5-Methyltetrazine is a click chemistry reagent containing a methyltetrazine group. Sulfo-Cy5-Methyltetrazine acts as a fluorophore linker for trans-cyclooctene-based labeling. Sulfo-Cy5-Methyltetrazine shows good stability at physiological pH and is also highly reactive towards cyclooctene.

HY-D2531

Cy5-PEG5000-SH	Fluorescent Dyes
Cy5-PEG5000-SH is a fluorescent labeling reagent that combines Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.

HY-151713

Sulfo-Cy3-Methyltetrazine	Fluorescent Dyes
Sulfo-Cy3-Methyltetrazine (figure 7 compound 5) is a click chemistry reagent containing methyltetrazine and a water-soluble dye. Sulfo-Cy3-Methyltetrazine shows good stability at physiological pH. Sulfo-Cy3-Methyltetrazine can be coupled to trans-cyclooctene and is also highly reactive towards cyclooctene .

HY-D2556

Cy5.5-PEG1000-SH	Fluorescent Dyes
Cy5.5-PEG1000-SH is a fluorescent labeling reagent that combines Cy5.5 (HY-D0924) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.

HY-D1886

Vari Fluor 647 SE

Fluorescent Dyes

Vari Fluor 647 SE is a fluorescent dye, SE stands for "succinimidyl ester". Vari Fluor 647 SE belongs to the Vari Fluor family of labeling reagents used in cell and molecular biology research. Vari Fluor 647 SE can react with an amino group to form a covalent bond, thereby introducing Vari Fluor 647 dye into the target molecule or cell. Vari Fluor 647 SE is a reactive dye that produces a fluorescent signal after binding to a target molecule or cell.

HY-D2532

Cy5-PEG10000-SH	Fluorescent Dyes
Cy5-PEG10000-SH is a fluorescent labeling reagent that combines Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.

HY-D2589

Cy7.5 PEG-SH	Fluorescent Dyes
Cy7.5 PEG-SH is a fluorescent labeling reagent that combines CY7.5 (HY-D0926) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em = 770/820 nm).

HY-W1048843AGL

4-Arm PEG5000-NH2 (GMP Like)

4-Arm PEG5000-amine (GMP Like)

Fluorescent Dyes

4-Arm PEG5000-NH2 (GMP Like) (4-Arm PEG5000-amine (GMP Like)) is 4-Arm PEG-NH2 (HY-W1048843A) produced by using GMP like guidelines. GMP like small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. 4-Arm PEG5000-NH2 is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .

HY-D2752

Cy5.5 dimethyl	Fluorescent Dyes
Cy5.5 dimethyl is a free non-activated dye and can be used as a non-reactive fluorophore for experiment controls and instrument calibration. It is a non-sulfonated reagent with good solubility in organic solvents and limited aquous solubility.

HY-D1352

Sulfo-Cyanine7 NHS ester potassium	Fluorescent Dyes
Sulfo-Cyanine7 NHS ester potassium is an amine-reactive succinimide ester. Sulfo-Cyanine7 NHS ester reagent allows to prepare sulfo-Cyanine7-labeled biomolecules, such as proteins, with ease. Dye labeled molecules can be subsequently used for various research and agent design related experiments.

HY-D2740

ROX azide, 6-isomer	Fluorescent Dyes
ROX azide, 6-isomer is an alkyne-reactive derivative of ROX (Rhodamine X, Rhodamine 101) dye. ROX is a red-emitting fluorophore possessing high brightness and fluorescence quantum yield. This reagent is a pure 6-isomer. It is used for labeling alkyne and cycloalkyne-containing biomolecules via copper-catalyzed and copper-free click chemistry reactions.

HY-D2509

Cy3-PEG1000-SH	Fluorescent Dyes
Cy3-PEG1000-SH is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds .

HY-D3049

5(6)-carbonylated rhodamine 110 NHS ester	Fluorescent Dyes
5(6)-carbonylated rhodamine 110 NHS ester is a reactive ester fluorescent reagent based on 5(6)-carbonylated rhodamine 110. NHS ester is a highly reactive ester capable of covalently coupling with primary amine groups in molecules such as proteins, peptides, amino sugars, and nucleic acids to form stable amide bonds (Ex/Em = 502/527 nm).

HY-D3050

5(6)-carbonylated rhodamine 110 X NHS ester	Fluorescent Dyes
5(6)-carbonylated rhodamine 110 X NHS ester is a reactive ester fluorescent reagent based on 5(6)-carbonylated rhodamine 110 X. NHS ester is a highly reactive ester capable of covalently coupling with primary amine groups in molecules such as proteins, peptides, amino sugars, and nucleic acids to form stable amide bonds (Ex/Em = 496/522 nm).

HY-D3053

5(6)-Rhodamine 6G NHS ester	Fluorescent Dyes
5(6)-Rhodamine 6G NHS ester is a reactive ester fluorescent reagent based on Rhodamine 6G (HY-D0309). NHS ester is a highly reactive ester capable of covalently coupling with primary amine groups in molecules such as proteins, peptides, amino sugars, and nucleic acids to form stable amide bonds (Ex/Em = 526/547 nm).

HY-42360G

SMCC

Fluorescent Dyes

SMCC (GMP) is the GMP level of SMCC (HY-42360). GMP guidelines are used to produce SMCC (HY-42360) (GMP). GMP small molecules works appropriately as an auxiliary reagent for cell research manufacture. SMCC (GMP) is a protein crosslinker. SMCC (GMP) contains an amine-reactive N-hydroxysuccinimide ester and a sulfhydryl-reactive maleimide group that can be used in the conjugation of proteins. SMCC-conjugated antigen coupled spleen cells to induce antigen-specific immune responses.

HY-D3241

CD649.2	Fluorescent Dyes
CD649.2 is a red-emitting copper-targeted acylimidazole-reactive Fluorescent probe and a highly specific Cu ²⁺ detection reagent. CD649.2 enables visualization of labile Cu ²⁺ pools and their dynamic changes in living cells .

HY-D3346

Dusquench1 NHS ester	Fluorescent Dyes
Dusquench1 NHS ester is an amino-reactive fluorescent quencher (it does not emit light and has no emission wavelength, Ex = 480-580 nM), specially designed for labeling proteins, oligonucleotides and other biopolymers containing primary amines. It is a core reagent in the fields of qPCR probes, FRET detection and molecular beacons.

HY-D2530

Cy5-PEG3400-SH	Fluorescent Dyes
Cy5-PEG3400-SH is a fluorescent labeling reagent that combines Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.

HY-D2512

Cy3-PEG5000-SH	Fluorescent Dyes
Cy3-PEG5000-SH is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds .

HY-D2557

Cy5.5-PEG3400-SH	Fluorescent Dyes
Cy5.5-PEG3400-SH is a fluorescent labeling reagent that combines Cy5.5 (HY-D0924) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.

HY-D2559

Cy5.5-PEG10000-SH	Fluorescent Dyes
Cy5.5-PEG10000-SH is a fluorescent labeling reagent that combines Cy5.5 (HY-D0924) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.

HY-D2558

Cy5.5-PEG5000-SH	Fluorescent Dyes
Cy5.5-PEG5000-SH is a fluorescent labeling reagent that combines Cy5.5 (HY-D0924) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.

HY-W1048843AG

4-Arm PEG5000-NH2

4-Arm PEG5000-amine

Fluorescent Dyes

4-Arm PEG5000-NH2 (GMP) (4-Arm PEG5000-amine (GMP)) is 4-Arm PEG-NH2 (HY-W1048843A) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. 4-Arm PEG5000-NH2 is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .

Cat. No.	Product Name	Type

HY-W441011

DSPE-NHS	Biochemical Assay Reagents
DSPE-NHS is a bioconjugation phospholipid molecule with two hydrophobic lipid tails. DSPE-NHS is a self-assembling reagent which forms lipid bilayer in aqueous solution. The NHS-ester is reactive with N-terminal of protein/peptide or other amine molecule to form a stable amide linkage. DSPE-NHS labels antibodies. DSPE-NHS can be used to prepare liposomes as agent nanocarrier .

HY-100215

Biotin Hydrazide 2 Publications Verification	Biochemical Assay Reagents
Biotin Hydrazide is a carbonyl-reactive biotinylation reagent, which is a carbonyl probe.

HY-W879045

Endo-BCN-PEG5-amine Endo-BCN-PEG5-NH2	Biochemical Assay Reagents
Endo-BCN-PEG5-amine (Endo-BCN-PEG5-NH2) is a click chemistry crosslinker reagent. The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc .

HY-77961

6-Maleimidocaproic acid hydrazide TFA N-ε-Maleimidocaproic acid hydrazide TFA	Biochemical Assay Reagents
6-Maleimidocaproic acid hydrazide TFA is a carbonyl and sulfhydryl reactive heterobifunctional crosslinking reagent .

HY-D0878

TAPSO	Biochemical Assay Reagents
TAPSO is a commonly used biological buffer and pH-stabilizing reagent, with an effective pH range of 7-8 and a pKa range of 7.5-9. TAPSO contains a Tris group, exhibits considerable reactivity, and can interact with zwitterionic glycine peptides .

HY-21626

4-Tolylboronic acid

p-Tolylboronic acid

Biochemical Assay Reagents

4-Tolylboronic acid is an organoboron compound with important chemical applications. It can be used as an important intermediate in organic synthesis for the synthesis of organic compounds such as drugs, pesticides, and cosmetics, as well as for the research of coordination chemistry and material science. Due to its high chemical reactivity, 4-Tolylboronic acid has become a widely used reagent in organic synthesis.

HY-W051391

1,4,7-Trimethyl-1,4,7-triazonane

Me3TACN

Biochemical Assay Reagents

1,4,7-Trimethyl-1,4,7-triazonane, also known as TMT or trimethylenetris(aziridine), is a cyclic organic compound. TMT is commonly used as a crosslinking agent and a precursor for polymer and resin synthesis. In addition, it is used as a stabilizer in the production of polyurethane foam and as a curing agent for epoxy resins. Due to its high reactivity and stability, TMT is considered to be a versatile and efficient reagent in various applications.

HY-176509A

DSPE-PEG2000-CHO

Biochemical Assay Reagents

DSPE-PEG2000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG2000-CHO can be used for drug delivery .

HY-125501

Biotin-XX hydrazide Biotin-(AC5)2-hydrazide	Biochemical Assay Reagents
Biotin-XX hydrazide (Biotin-(AC5)2-hydrazide) is a carbonyl-reactive biotinylation reagent which contains two aminohexanoic acid spacers. Biotin-XX hydrazide has higher efficiency of avidin-binding .

HY-176509C

DSPE-PEG5000-CHO

Biochemical Assay Reagents

DSPE-PEG5000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG5000-CHO can be used for drug delivery .

HY-176509

DSPE-PEG1000-CHO

Biochemical Assay Reagents

DSPE-PEG1000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG1000-CHO can be used for drug delivery .

HY-W879025

Endo-BCN-PEG8-amine Endo-BCN-PEG8-NH2	Biochemical Assay Reagents
Endo-BCN-PEG8-amine (Endo-BCN-PEG8-NH2) is a click chemistry crosslinker reagent. The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc .

HY-W1048843AGL

4-Arm PEG5000-NH2 (GMP Like)

4-Arm PEG5000-amine (GMP Like)

Biochemical Assay Reagents

HY-131097

Malachite green isothiocyanate	Biochemical Assay Reagents
Malachite green isothiocyanate is an amine-reactive probe that reacts with amines to give the corresponding thiourea. Malachite green isothiocyanate is a reagent that has been used for the measurement of concentration of protein .

HY-W879044

Endo-BCN-PEG15-amine Endo-BCN-PEG15-NH2	Biochemical Assay Reagents
Endo-BCN-PEG15-amine (Endo-BCN-PEG15-NH2) is a click chemistry crosslinker reagent. The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc .

HY-W1049129C

Mal-PEG20000-mal	Biochemical Assay Reagents
Mal-PEG20000-mal is a linear bifunctional PEG reagent with reactive maleimide groups. Mal-PEG20000-mal can be used for drug delivery .

HY-W1049129B

Mal-PEG10000-mal	Biochemical Assay Reagents
Mal-PEG10000-mal is a linear bifunctional PEG reagent with reactive maleimide groups. Mal-PEG10000-mal can be used for drug delivery .

HY-W1048552

Mal-PEG1000-mal	Biochemical Assay Reagents
Mal-PEG1000-mal is a linear bifunctional PEG reagent with reactive maleimide groups. Mal-PEG1000-mal can be used for drug delivery .

HY-W009330

TAPSO sodium	Biochemical Assay Reagents
TAPSO sodium is a commonly used biological buffer and pH-stabilizing reagent, with an effective pH range of 7-8 and a pKa range of 7.5-9. TAPSO sodium contains a Tris group, exhibits considerable reactivity, and can interact with zwitterionic glycine peptides .

HY-176509D

DSPE-PEG10000-CHO

Biochemical Assay Reagents

DSPE-PEG10000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG10000-CHO can be used for drug delivery .

HY-176509B

DSPE-PEG3400-CHO

Biochemical Assay Reagents

DSPE-PEG3400-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG3400-CHO can be used for drug delivery .

HY-176509H

DSPE-PEG40000-CHO

Biochemical Assay Reagents

DSPE-PEG40000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG40000-CHO can be used for drug delivery .

HY-W1049129D

Mal-PEG40000-mal	Biochemical Assay Reagents
Mal-PEG40000-mal is a linear bifunctional PEG reagent with reactive maleimide groups. Mal-PEG40000-mal can be used for drug delivery .

HY-100215R

Biotin Hydrazide (Standard)	Biochemical Assay Reagents
Biotin Hydrazide (Standard) is the analytical standard of Biotin Hydrazide (HY-100215). This product is intended for research and analytical applications. Biotin Hydrazide is a carbonyl-reactive biotinylation reagent, which is a carbonyl probe.

HY-42360G

SMCC

Biochemical Assay Reagents

HY-176509E

DSPE-PEG20000-CHO

Biochemical Assay Reagents

DSPE-PEG20000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG20000-CHO can be used for drug delivery .

HY-W1048843AG

4-Arm PEG5000-NH2

4-Arm PEG5000-amine

Biochemical Assay Reagents

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N15963

18:1 DBCO PE ammonium	Lipid	Biochemical Assay Reagents
18:1 DBCO PE ammonium is a functionalized lipid that combines the biocompatible properties of phosphatidylethanolamine (PE) with the reactive dibenzocyclooctyne (DBCO) group. 18:1 DBCO PE ammonium is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .

Cat. No.	Product Name		Classification

HY-136205

IA-Alkyne 4 Publications Verification Iodoacetamide-alkyne; N-Hex-5-ynyl-2-iodo-acetamide		Alkynes
IA-Alkyne (Iodoacetamide-alkyne; N-Hex-5-ynyl-2-iodo-acetamide) is a TRP channel (TRPC) agonist and has the potential for the study of respiratory infection . IA-Alkyne can be used to develop an isotopically tagged probe for quantitative *cysteine-reactivity* profiling . IA-Alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W879045

Endo-BCN-PEG5-amine Endo-BCN-PEG5-NH2		BCN
Endo-BCN-PEG5-amine (Endo-BCN-PEG5-NH2) is a click chemistry crosslinker reagent. The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc .

HY-136426

Trifludimoxazin		Alkynes
Trifludimoxazin is a click chemistry reagent, a protoporphyrinogen oxidase (PPO) inhibitor and herbicide. Trifludimoxazin inhibits PPO, accumulates reactive oxygen species, damages cell membranes, and thereby causes weed death. Trifludimoxazin exhibits high-efficiency activity in controlling broadleaf weeds and grassy weeds .

HY-151776

Cy3 methyltetrazine TZ-Cy3		Labeling and Fluorescence Imaging Tetrazine
Cy3 methyltetrazine (TZ-Cy3) is a click chemistry reagent with methyltetrazine building blocks that is highly reactive towards cyclooctene. Cy3 methyltetrazine is also a tetrazine-modified fluorescent probe that can be used to analyze protein phosphorylation in solution and living cells .

HY-D0820

CY5-YNE Sulfo-Cyanine5-alkyne		Labeling and Fluorescence Imaging Alkynes
CY5-YNE (Sulfo-Cyanine5-alkyne) is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides (Ex: 650 nM; Em: 680 nm). CY5-YNE is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-151712

Sulfo-Cy5-Methyltetrazine		Labeling and Fluorescence Imaging Tetrazine
Sulfo-Cy5-Methyltetrazine is a click chemistry reagent containing a methyltetrazine group. Sulfo-Cy5-Methyltetrazine acts as a fluorophore linker for trans-cyclooctene-based labeling. Sulfo-Cy5-Methyltetrazine shows good stability at physiological pH and is also highly reactive towards cyclooctene.

HY-151713

Sulfo-Cy3-Methyltetrazine		Labeling and Fluorescence Imaging Tetrazine
Sulfo-Cy3-Methyltetrazine (figure 7 compound 5) is a click chemistry reagent containing methyltetrazine and a water-soluble dye. Sulfo-Cy3-Methyltetrazine shows good stability at physiological pH. Sulfo-Cy3-Methyltetrazine can be coupled to trans-cyclooctene and is also highly reactive towards cyclooctene .

HY-151792

Pomalidomid-C6-PEG3-butyl-N3		Azide PROTAC Synthesis
Pomalidomid-C6-PEG3-butyl-N3 is a click chemistry reagent containing an azide group. Pomalidomid-C6-PEG3-butyl-N3 also is a crosslinker-E3 ligase ligand conjugate, which be used in click reactive protein degrader building block for PROTAC research. Pomalidomid-C6-PEG3-butyl-N3 also can be used in the template for synthesis of targeted protein degrader . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-173569

DBCO-propargyl-PEG5-TFP ester		Alkynes DBCO
DBCO-propargyl-PEG5-TFP ester is an amine-reactive labeling reagent. DBCO-propargyl-PEG5-TFP ester contains a DBCO group, which can undergo a strain-promoted alkyne-azide cycloaddition (SPAAC) reaction with molecules containing an azide group ^{[1] ^.}

HY-151791

(S,R,S)-AHPC-C6-PEG3-butyl-N3		Azide
(S,R,S)-AHPC-C6-PEG3-butyl-N3 is a click chemistry reagent containing an azide group. (S,R,S)-AHPC-C6-PEG3-butyl-N3 serves as crosslinker-E3 ligase ligand conjugate, Click reactive protein degrader building block for PROTAC research, Template for synthesis of targeted protein degrader, VH032 conjugate . (S,R,S)-AHPC-C6-PEG3-butyl-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-151687

Fmoc-L-Tyr(2-azidoethyl)-OH		Azide
Fmoc-L-Tyr(2-azidoethyl)-OH is a click chemistry reagent containing an azide group. Fmoc-L-Tyr(2-azidoethyl)-OH is unnatural Fmoc-protected Tyrosine derivative bears an azidoethyl substitution as reactive handle e.g. for biorthogonal conjugations, via a Cu(I)-catalyzed 1,3-dipolar Click cycloaddition with alkynes. And azido-UAAs can be employed as IR reporters . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-172513

Methyltetrazine-PEG11-DBCO		DBCO Tetrazine
Methyltetrazine-PEG11-DBCO is a TCO reactive reagent with a DBCO group and water-soluble PEG spacer. This reagent can be used to convert azido-containing peptides or proteins into tetrazine-modified peptides or protein without catalyst or axillary reagents. DBCO is commonly used for copper-free Click Chemistry reactions.

HY-W800723

Methyltetrazine-PEG2-DBCO		DBCO
Methyltetrazine-PEG2-DBCO is a TCO reactive reagent with a DBCO group and water-soluble PEG spacer. This reagent can be used to convert azido-containing peptides or proteins into tetrazine-modified peptides or protein without catalyst or axillary reagents. DBCO is commonly used for copper-free Click Chemistry reactions.

HY-W800724

Methyltetrazine-PEG4-DBCO		DBCO
Methyltetrazine-PEG4-DBCO is a PEG linker with a terminal TCO reactive reagent and a DBCO group. DBCO is commonly used for copper-free Click Chemistry reactions. Methyltetrazine can be used to convert azido-containing peptides or proteins into tetrazine-modified peptides or protein without catalyst or axillary reagents.

HY-D2740

ROX azide, 6-isomer		Azide
ROX azide, 6-isomer is an alkyne-reactive derivative of ROX (Rhodamine X, Rhodamine 101) dye. ROX is a red-emitting fluorophore possessing high brightness and fluorescence quantum yield. This reagent is a pure 6-isomer. It is used for labeling alkyne and cycloalkyne-containing biomolecules via copper-catalyzed and copper-free click chemistry reactions.

HY-W591390

6-Azidohexanoic acid STP ester		Azide
6-Azidohexanoic Acid STP Ester is an amine-reactive, water-soluble labeling reagent with an azide group and a terminal 4-Sulfo-2,3,5,6-tetrafluorophenyl (STP) group. 6-Azidohexanoic Acid STP Ester is used to modify proteins, antibodies, and other amine-containing biopolymers in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. STP esters can react with primary amines, forming covalent amide bonds, and typically display much better stability toward hydrolysis in aqueous media, resulting in more efficiency and better reproducible labeling of biopolymers.

HY-W800653

N-(Azido-PEG3)-NH-PEG3-t-butyl ester		Azide
N-(Azido-PEG3)-NH-PEG3-t-butyl ester is a click chemistry reagent with a terminal azide group and secondary amine NH group. NH group is reactive with NHS ester, The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The azide group can participate in Click Chemistry.

Cat. No.	Product Name		Classification

HY-W441011

DSPE-NHS		Phospholipids
DSPE-NHS is a bioconjugation phospholipid molecule with two hydrophobic lipid tails. DSPE-NHS is a self-assembling reagent which forms lipid bilayer in aqueous solution. The NHS-ester is reactive with N-terminal of protein/peptide or other amine molecule to form a stable amide linkage. DSPE-NHS labels antibodies. DSPE-NHS can be used to prepare liposomes as agent nanocarrier .

HY-176509A

DSPE-PEG2000-CHO		Pegylated Lipids
DSPE-PEG2000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG2000-CHO can be used for drug delivery .

HY-W440927

Stearic acid-PEG2000-NHS		Pegylated Lipids
Stearic acid-PEG2000-NHS is an amphiphatic PEG polymer which forms micelles in an aqueous solution for drug-loaded nanoparticles. The NHS ester is reactive with amine to form a stable amide bond. Reagent grade, for research purpose.

HY-176509C

DSPE-PEG5000-CHO		Pegylated Lipids
DSPE-PEG5000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG5000-CHO can be used for drug delivery .

HY-176509

DSPE-PEG1000-CHO		Pegylated Lipids
DSPE-PEG1000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG1000-CHO can be used for drug delivery .

HY-W440883

DSPE-PEG2000-Ald		Pegylated Lipids
DSPE-PEG2000-Ald is a phospholipid polyPEG which can self-assemble to form lipid bilayer in aqueous solution. The polymer can be used to prepare liposome as a drug delivery vehicle for administration of drugs or nutrients, such as mRNA vaccines. The aldehyde is reactive with aminooxy to form a stable oxime linkage or with amine at pH < 7 to form a reversible imine bond. Reagent grade, for research use only.

HY-176509D

DSPE-PEG10000-CHO		Pegylated Lipids
DSPE-PEG10000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG10000-CHO can be used for drug delivery .

HY-176509B

DSPE-PEG3400-CHO		Pegylated Lipids
DSPE-PEG3400-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG3400-CHO can be used for drug delivery .

HY-176509H

DSPE-PEG40000-CHO		Pegylated Lipids
DSPE-PEG40000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG40000-CHO can be used for drug delivery .

HY-176509E

DSPE-PEG20000-CHO		Pegylated Lipids
DSPE-PEG20000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG20000-CHO can be used for drug delivery .

Targets Recommended: Reactive Oxygen Species (ROS)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-42360G

SMCC	ADC Linker	Inflammation/Immunology Cancer
SMCC (GMP) is the GMP level of SMCC (HY-42360). GMP guidelines are used to produce SMCC (HY-42360) (GMP). GMP small molecules works appropriately as an auxiliary reagent for cell research manufacture. SMCC (GMP) is a protein crosslinker. SMCC (GMP) contains an amine-reactive N-hydroxysuccinimide ester and a sulfhydryl-reactive maleimide group that can be used in the conjugation of proteins. SMCC-conjugated antigen coupled spleen cells to induce antigen-specific immune responses.

HY-W1048843AG

4-Arm PEG5000-NH2 4-Arm PEG5000-amine	Biochemical Assay Reagents	Others
4-Arm PEG5000-NH2 (GMP) (4-Arm PEG5000-amine (GMP)) is 4-Arm PEG-NH2 (HY-W1048843A) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. 4-Arm PEG5000-NH2 is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .

HY-W1048843AGL

4-Arm PEG5000-NH2 (GMP Like) 4-Arm PEG5000-amine (GMP Like)	Biochemical Assay Reagents	Others
4-Arm PEG5000-NH2 (GMP Like) (4-Arm PEG5000-amine (GMP Like)) is 4-Arm PEG-NH2 (HY-W1048843A) produced by using GMP like guidelines. GMP like small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. 4-Arm PEG5000-NH2 is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .

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