2. Search Result
Search Result
Results for "

sperm motility

" in MedChemExpress (MCE) Product Catalog:

16

Inhibitors & Agonists

1

Peptides

5

Natural
Products

1

Recombinant Proteins

1

Isotope-Labeled Compounds

3

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-121389
    Hexadecanamide

    Palmitamide

    		 Bacterial NF-κB PPAR Infection Inflammation/Immunology
    Hexadecanamide (Palmitamide) is a fatty acid amide that has orally active anti-allergic, antioxidant, and neuroprotective effects. Hexadecanamide exerts protective effects in Staphylococcus aureus- and SARA-induced mastitis. Hexadecanamide suppresses S. aureus-induced activation of the NF-κB pathway and improves blood-milk barrier integrity. Hexadecanamide activates PPARα. Hexadecanamide enhances sperm motility in vitro. Hexadecanamide can be studied in research for mastitis and asthenozoospermia .
    Hexadecanamide
  • HY-N2026
    Propylparaben
    1 Publications Verification

    Propyl parahydroxybenzoate; Propyl 4-hydroxybenzoate

    		 Environmental Pollutants Endogenous Metabolite Apoptosis Bacterial Infection
    Propylparaben (Propyl parahydroxybenzoate) is an antibacterial preservative that can be produced by plants and bacteria. Propylparaben is commonly used in cosmetics, pharmaceuticals and foods. Propylparaben disrupts follicular growth and steroidogenic function by altering cell cycle, apoptosis and steroidogenic pathways. Propylparaben also reduced sperm count and motility in rats .
    Propylparaben
  • HY-17519
    Novaluron

    		Environmental Pollutants Insecticide Infection
    Novaluron is a chemical with insecticide properties, an insect growth regulator, and has adverse effects on mouse sperm .
    Novaluron
  • HY-18740A
    Trequinsin hydrochloride

    HL 725

    		 Phosphodiesterase (PDE) Neurological Disease Metabolic Disease Cancer
    Trequinsin hydrochloride (HL 725) is a PDE inhibitor, CatSper channel activator, and sperm potassium channel modulator. Trequinsin hydrochloride targets PDE3 with an IC50 of <1 nM. Trequinsin hydrochloride enhances currents and elevates intracellular calcium and cGMP levels via direct activation of the CatSper channel, while inhibiting the outward current conductance of sperm potassium channels. Without inducing premature acrosome reaction, Trequinsin hydrochloride significantly enhances sperm hyperactivated motility, forward motility, and the ability to penetrate viscous media. Trequinsin hydrochloride exerts age-specific positive inotropic and positive lusitropic effects on rabbit ventricular papillary muscles. Trequinsin hydrochloride has been used in studies on the mechanisms underlying male infertility (e.g., asthenozoospermia) .
    Trequinsin hydrochloride
  • HY-W098348
    N-Methyltaurine

    		Parasite Metabolic Disease
    N-Methyltaurine is a taurine-derived metabolite with a minimum effective concentration of 10 μM for maintaining hamster sperm motility. N-Methyltaurine is the dominant osmolyte of Vespermum virulentum .
    N-Methyltaurine
  • HY-164911
    VU0546110

    		Potassium Channel Endocrinology
    VU0546110 is a selective inhibitor of the sperm-specific potassium channel SLO3, with IC50s of 1.287 μM (SLO3) and 59.80 μM (SLO1) in HEK293 cells, respectively. VU0546110 blocks heterologous SLO3 currents and endogenous K + currents in human sperm. VU0546110 halts sperm hyperpolarization, induced acrosome reaction, and hyper-activated motility. VU0546110 has contraceptive potential .
    VU0546110
  • HY-N2026R
    Propylparaben (Standard)

    Propyl parahydroxybenzoate (Standard); Propyl 4-hydroxybenzoate (Standard)

    		 Reference Standards Endogenous Metabolite Bacterial Apoptosis Infection
    Propylparaben (Standard) is the analytical standard of Propylparaben. This product is intended for research and analytical applications. Propylparaben (Propyl parahydroxybenzoate) is an antibacterial preservative that can be produced by plants and bacteria. Propylparaben is commonly used in cosmetics, pharmaceuticals and foods. Propylparaben disrupts follicular growth and steroidogenic function by altering cell cycle, apoptosis and steroidogenic pathways. Propylparaben also reduced sperm count and motility in rats .
    Propylparaben (Standard)
  • HY-W654020
    Propyl paraben-13C6

    Propyl parahydroxybenzoate-13C6; Propyl 4-hydroxybenzoate-13C6

    		 Isotope-Labeled Compounds Apoptosis Endogenous Metabolite Bacterial Infection
    Propyl paraben- 13C6 (Propyl parahydroxybenzoate- 13C6) is 13C labeled Propylparaben. Propylparaben (Propyl parahydroxybenzoate) is an antibacterial preservative that can be produced by plants and bacteria. Propylparaben is commonly used in cosmetics, pharmaceuticals and foods. Propylparaben disrupts follicular growth and steroidogenic function by altering cell cycle, apoptosis and steroidogenic pathways. Propylparaben also reduced sperm count and motility in rats .
    Propyl paraben-13C6
  • HY-153818
    Sperm motility agonist-1

    		Drug Derivative Endocrinology
    Sperm motility agonist-1 (compound 745) is a Sperm motility agonist. Sperm motility agonist-1 can be used in studies of infertility and enhancement of fertility .
    Sperm motility agonist-1
  • HY-153819
    Sperm motility agonist-2

    		Mitochondrial Metabolism Endocrinology
    Sperm motility agonist-2 (compound 797) is a Sperm motility agonist, that may affect mitochondrial function. Sperm motility agonist-2 can be used in studies of infertility and enhancement of fertility .
    Sperm motility agonist-2
  • HY-P0245
    Speract

    		Mitochondrial Metabolism Metabolic Disease
    Speract, a sea urchin egg peptide that regulates sperm motility, also stimulates sperm mitochondrial metabolism.
    Speract
  • HY-136855
    MitoPBN

    		Sirtuin AMPK PGC-1α Apoptosis Reactive Oxygen Species (ROS) Metabolic Disease
    MitoPBN is a AMPK/SIRT3/PGC-1α axis modulator, reactive oxygen species scavenger and mitochondrial function enhancer. MitoPBN increases the phosphorylation level of AMPK, restores SIRT3 expression and reverses the down-regulation of PGC-1α, thereby promoting mitochondrial biogenesis. MitoPBN regulates glucose metabolism, reduces blood glucose by inhibiting hepatic gluconeogenesis and increasing hepatic glucose uptake, while scavenging mitochondrial superoxide anion/hydrogen peroxide, maintaining membrane potential and increasing ATP production. MitoPBN also reduces cell apoptosis, improves sperm motility, survival rate and membrane integrity, but may induce reductive stress in cryopreserved sperm at high concentrations. MitoPBN is widely applicable to research related to diabetes and type 2 diabetes .
    MitoPBN
  • HY-121389R
    Hexadecanamide (Standard)

    Palmitamide (Standard)

    		 Bacterial NF-κB PPAR Reference Standards Infection Inflammation/Immunology
    Hexadecanamide (Standard) is the analytical standard of Hexadecanamide. This product is intended for research and analytical applications. Hexadecanamide (Palmitamide) is a fatty acid amide that has orally active anti-allergic, antioxidant, and neuroprotective effects. Hexadecanamide exerts protective effects in Staphylococcus aureus- and SARA-induced mastitis. Hexadecanamide suppresses S. aureus-induced activation of the NF-κB pathway and improves blood-milk barrier integrity. Hexadecanamide activates PPARα. Hexadecanamide enhances sperm motility in vitro. Hexadecanamide can be studied in research for mastitis and asthenozoospermia .
    Hexadecanamide (Standard)
  • HY-171129
    EP055

    		Ser/Thr Protease Endocrinology
    EP055 is a non-hormonal male contraceptive. EP055 targets to sperm protein EPPIN and inhibits anti-EPPIN antibodies from binding EPPIN with an IC50 of 1121 μM. EP055 can inhibit sperm motility (IC50 = 199.5 μM) by reducing the internal pH and Ca 2+ levels of the sperm, thereby causing the sperm to aggregate. EP055 can be used for development of male contraceptive .
    EP055
  • HY-18740
    Trequinsin

    HL 725 free base

    		 Phosphodiesterase (PDE) Endocrinology
    Trequinsin (HL 725 free base) is a PDE inhibitor, CatSper channel activator, and sperm potassium channel modulator. Trequinsin targets PDE3 with an IC50 of <1 nM. Trequinsin enhances currents and elevates intracellular calcium and cGMP levels via direct activation of the CatSper channel, while inhibiting the outward current conductance of sperm potassium channels. Without inducing premature acrosome reaction, Trequinsin significantly enhances sperm hyperactivated motility, forward motility, and the ability to penetrate viscous media. Trequinsin exerts age-specific positive inotropic and positive lusitropic effects on rabbit ventricular papillary muscles. Trequinsin has been used in studies on the mechanisms underlying male infertility (e.g., asthenozoospermia) .
    Trequinsin
  • HY-N18905
    α-D-Glucosyl hesperidin

    		Apoptosis Bcl-2 Family Caspase SOD Endocrinology
    α-D-Glucosyl hesperidin is an orally effective structural modification derivative of Hesperidin (HY-15337) with anti-apoptotic (apoptosis) and antioxidant activities. α-D-Glucosyl hesperidin upregulates the expression of the Bcl-2 gene, while downregulating the expressions of the Bax and caspase-3 genes. α-D-Glucosyl hesperidin increases total antioxidant capacity, SOD and catalase levels, and decreases malondialdehyde and glutathione levels. α-D-Glucosyl hesperidin improves sperm motility, viability and plasma membrane function, while restoring reproductive organ weight and seminiferous tubule structure. α-D-Glucosyl hesperidin increases fertility index and exerts a synergistic protective effect with Proanthocyanidins (HY-N0794) in male rats with testicular ischemia-reperfusion injury. α-D-Glucosyl hesperidin can be used in the research of testicular ischemia-reperfusion injury .
    α-D-Glucosyl hesperidin

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: