1. Metabolic Enzyme/Protease
  2. Ser/Thr Protease
  3. EP055

EP055 is a non-hormonal male contraceptive. EP055 targets to sperm protein EPPIN and inhibits anti-EPPIN antibodies from binding EPPIN with an IC50 of 1121 μM. EP055 can inhibit sperm motility (IC50 = 199.5 μM) by reducing the internal pH and Ca2+ levels of the sperm, thereby causing the sperm to aggregate. EP055 can be used for development of male contraceptive.

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EP055

EP055 Chemical Structure

CAS No. : 2411173-40-3

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Description

EP055 is a non-hormonal male contraceptive. EP055 targets to sperm protein EPPIN and inhibits anti-EPPIN antibodies from binding EPPIN with an IC50 of 1121 μM. EP055 can inhibit sperm motility (IC50 = 199.5 μM) by reducing the internal pH and Ca2+ levels of the sperm, thereby causing the sperm to aggregate. EP055 can be used for development of male contraceptive[1].

Molecular Weight

423.40

Formula

C15H17N7O6S

CAS No.
SMILES

O=C(CSC1=NC(NC2=CC=C(C(O)=C2)NC(C)=O)=NC(NNC(OC)=O)=N1)O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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EP055
Cat. No.:
HY-171129
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